Incidental Mutation 'R1471:Cd109'
| ID |
164900 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cd109
|
| Ensembl Gene |
ENSMUSG00000046186 |
| Gene Name |
CD109 antigen |
| Synonyms |
Gov platelet alloantigens, 9930012E15Rik |
| MMRRC Submission |
039524-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1471 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
78522828-78623535 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 78561869 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 220
(V220I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091330
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093812]
|
| AlphaFold |
Q8R422 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093812
AA Change: V220I
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000091330
Gene: ENSMUSG00000046186
AA Change: V220I
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
129 |
220 |
1.5e-16 |
PFAM |
|
A2M_N_2
|
470 |
601 |
8.89e-32 |
SMART |
|
A2M
|
695 |
786 |
2.07e-32 |
SMART |
|
Pfam:Thiol-ester_cl
|
912 |
941 |
2.6e-20 |
PFAM |
|
Pfam:A2M_comp
|
961 |
1197 |
1.9e-65 |
PFAM |
|
low complexity region
|
1265 |
1275 |
N/A |
INTRINSIC |
|
A2M_recep
|
1311 |
1395 |
2.06e-27 |
SMART |
|
low complexity region
|
1422 |
1437 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.6%
- 10x: 96.8%
- 20x: 94.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
PHENOTYPE: Mice homozygous for a null mutation display epidermal hyperplasia and thickening, sebaceous gland hyperplasia and transient impairment of hair growth. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930486L24Rik |
C |
A |
13: 61,001,336 (GRCm39) |
K130N |
probably damaging |
Het |
| Adam6a |
T |
A |
12: 113,508,013 (GRCm39) |
S129T |
probably damaging |
Het |
| Adamts10 |
T |
A |
17: 33,772,112 (GRCm39) |
F1087I |
probably damaging |
Het |
| Afp |
T |
A |
5: 90,651,541 (GRCm39) |
N385K |
possibly damaging |
Het |
| Ahnak |
T |
G |
19: 8,990,296 (GRCm39) |
|
probably benign |
Het |
| Akap6 |
A |
G |
12: 53,188,279 (GRCm39) |
T1898A |
probably benign |
Het |
| Antxr2 |
C |
A |
5: 98,123,199 (GRCm39) |
V283F |
possibly damaging |
Het |
| Asgr1 |
T |
C |
11: 69,946,919 (GRCm39) |
V55A |
possibly damaging |
Het |
| Asxl3 |
A |
G |
18: 22,649,411 (GRCm39) |
K467E |
probably damaging |
Het |
| Atp5f1a |
C |
A |
18: 77,868,969 (GRCm39) |
Q398K |
probably damaging |
Het |
| Atxn2 |
T |
A |
5: 121,924,437 (GRCm39) |
D455E |
probably damaging |
Het |
| B4galt6 |
C |
T |
18: 20,878,410 (GRCm39) |
A39T |
possibly damaging |
Het |
| C130073F10Rik |
C |
T |
4: 101,747,535 (GRCm39) |
E165K |
probably benign |
Het |
| Cabin1 |
A |
G |
10: 75,530,626 (GRCm39) |
C1519R |
probably damaging |
Het |
| Casp8ap2 |
C |
T |
4: 32,639,386 (GRCm39) |
R147* |
probably null |
Het |
| Ccdc88b |
A |
G |
19: 6,831,391 (GRCm39) |
L517P |
probably benign |
Het |
| Cd2ap |
T |
C |
17: 43,131,488 (GRCm39) |
K369R |
probably benign |
Het |
| Cd300c |
A |
G |
11: 114,850,614 (GRCm39) |
V63A |
probably benign |
Het |
| Cnot10 |
A |
G |
9: 114,420,619 (GRCm39) |
V741A |
probably benign |
Het |
| Col18a1 |
G |
T |
10: 76,932,040 (GRCm39) |
Q350K |
unknown |
Het |
| Crnkl1 |
T |
C |
2: 145,774,236 (GRCm39) |
K76E |
possibly damaging |
Het |
| Cryzl2 |
A |
G |
1: 157,298,291 (GRCm39) |
K227E |
probably benign |
Het |
| Cts6 |
G |
A |
13: 61,344,194 (GRCm39) |
T286I |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,491,820 (GRCm39) |
V392A |
probably damaging |
Het |
| Dcaf7 |
T |
A |
11: 105,937,573 (GRCm39) |
F65L |
probably benign |
Het |
| Dgke |
A |
C |
11: 88,946,320 (GRCm39) |
V160G |
possibly damaging |
Het |
| Dock8 |
C |
A |
19: 25,178,400 (GRCm39) |
Q2098K |
possibly damaging |
Het |
| Efhb |
T |
A |
17: 53,706,140 (GRCm39) |
D799V |
possibly damaging |
Het |
| Ephb2 |
T |
C |
4: 136,386,262 (GRCm39) |
D829G |
probably benign |
Het |
| Exosc1 |
A |
T |
19: 41,913,157 (GRCm39) |
S117R |
probably damaging |
Het |
| Fga |
T |
C |
3: 82,935,925 (GRCm39) |
S51P |
probably benign |
Het |
| Fmn1 |
T |
C |
2: 113,523,439 (GRCm39) |
F1141L |
possibly damaging |
Het |
| Foxm1 |
C |
T |
6: 128,350,837 (GRCm39) |
L713F |
probably damaging |
Het |
| Galnt4 |
A |
G |
10: 98,944,536 (GRCm39) |
E87G |
probably benign |
Het |
| Gamt |
T |
C |
10: 80,096,692 (GRCm39) |
D15G |
probably benign |
Het |
| Gm15557 |
C |
A |
2: 155,784,174 (GRCm39) |
D154E |
possibly damaging |
Het |
| Gnptab |
A |
G |
10: 88,281,625 (GRCm39) |
I1211V |
probably benign |
Het |
| Greb1 |
A |
T |
12: 16,761,775 (GRCm39) |
M535K |
probably damaging |
Het |
| Grm8 |
C |
A |
6: 27,363,308 (GRCm39) |
A736S |
possibly damaging |
Het |
| Hspa14 |
T |
C |
2: 3,492,645 (GRCm39) |
I373M |
probably benign |
Het |
| Ifi207 |
T |
A |
1: 173,557,629 (GRCm39) |
T370S |
unknown |
Het |
| Igf1r |
A |
G |
7: 67,653,585 (GRCm39) |
N41S |
probably damaging |
Het |
| Ikzf5 |
A |
T |
7: 130,993,496 (GRCm39) |
V224D |
probably damaging |
Het |
| Il10 |
C |
A |
1: 130,949,110 (GRCm39) |
Y90* |
probably null |
Het |
| Itga4 |
A |
G |
2: 79,117,376 (GRCm39) |
D394G |
probably benign |
Het |
| Kif21a |
A |
T |
15: 90,840,622 (GRCm39) |
S1165T |
probably benign |
Het |
| Krtap14 |
A |
G |
16: 88,622,515 (GRCm39) |
S155P |
probably damaging |
Het |
| Loxl2 |
A |
G |
14: 69,930,546 (GRCm39) |
N770S |
probably benign |
Het |
| Man2b1 |
A |
G |
8: 85,813,474 (GRCm39) |
D222G |
probably damaging |
Het |
| Mcub |
T |
A |
3: 129,709,464 (GRCm39) |
Y283F |
probably damaging |
Het |
| Meis3 |
T |
A |
7: 15,911,496 (GRCm39) |
Y64* |
probably null |
Het |
| Mfsd6 |
T |
A |
1: 52,748,716 (GRCm39) |
I50F |
probably benign |
Het |
| Micu2 |
T |
C |
14: 58,182,854 (GRCm39) |
T165A |
probably damaging |
Het |
| Mtcl1 |
T |
C |
17: 66,686,143 (GRCm39) |
E921G |
probably damaging |
Het |
| Muc5b |
A |
T |
7: 141,396,971 (GRCm39) |
N215Y |
unknown |
Het |
| Muc6 |
A |
G |
7: 141,234,176 (GRCm39) |
F772L |
possibly damaging |
Het |
| Myt1 |
A |
G |
2: 181,438,904 (GRCm39) |
D142G |
probably benign |
Het |
| Nol6 |
C |
T |
4: 41,120,281 (GRCm39) |
V479I |
probably benign |
Het |
| Nsun7 |
A |
G |
5: 66,441,572 (GRCm39) |
K414E |
probably benign |
Het |
| Nup210l |
A |
C |
3: 90,077,869 (GRCm39) |
I914L |
probably benign |
Het |
| Obox3 |
G |
A |
7: 15,360,875 (GRCm39) |
P88L |
probably benign |
Het |
| Or10ag57 |
A |
G |
2: 87,218,862 (GRCm39) |
Y271C |
probably damaging |
Het |
| Or4f4b |
T |
C |
2: 111,314,351 (GRCm39) |
L192P |
probably damaging |
Het |
| Or8h8 |
C |
T |
2: 86,752,922 (GRCm39) |
|
probably null |
Het |
| Or8w1 |
T |
C |
2: 87,466,014 (GRCm39) |
T26A |
probably benign |
Het |
| Pclo |
T |
C |
5: 14,730,441 (GRCm39) |
|
probably benign |
Het |
| Pcsk5 |
T |
C |
19: 17,545,688 (GRCm39) |
N745D |
probably damaging |
Het |
| Pdzrn3 |
T |
A |
6: 101,128,473 (GRCm39) |
N731I |
possibly damaging |
Het |
| Pkdrej |
T |
A |
15: 85,701,334 (GRCm39) |
Q1534L |
probably benign |
Het |
| Pramel28 |
T |
C |
4: 143,691,523 (GRCm39) |
N400S |
probably benign |
Het |
| Rell1 |
T |
A |
5: 64,093,428 (GRCm39) |
D109V |
probably damaging |
Het |
| Rplp0 |
C |
T |
5: 115,701,403 (GRCm39) |
T285I |
probably damaging |
Het |
| Sanbr |
A |
T |
11: 23,565,222 (GRCm39) |
M255K |
probably damaging |
Het |
| Sema3g |
C |
T |
14: 30,950,002 (GRCm39) |
R728C |
probably damaging |
Het |
| Slc15a2 |
A |
G |
16: 36,574,153 (GRCm39) |
Y536H |
probably damaging |
Het |
| Slc26a5 |
T |
A |
5: 22,021,962 (GRCm39) |
Y488F |
probably benign |
Het |
| Slc5a4a |
A |
T |
10: 76,022,362 (GRCm39) |
S566C |
probably damaging |
Het |
| Spink7 |
C |
T |
18: 62,729,275 (GRCm39) |
E21K |
possibly damaging |
Het |
| Src |
C |
T |
2: 157,299,107 (GRCm39) |
Q35* |
probably null |
Het |
| Srrm2 |
T |
A |
17: 24,039,770 (GRCm39) |
V2234E |
probably damaging |
Het |
| Stk36 |
A |
T |
1: 74,650,314 (GRCm39) |
Q282L |
probably benign |
Het |
| Tas2r118 |
T |
G |
6: 23,969,170 (GRCm39) |
E297A |
probably damaging |
Het |
| Terf1 |
A |
G |
1: 15,913,194 (GRCm39) |
Y385C |
probably damaging |
Het |
| Tmc3 |
T |
C |
7: 83,247,498 (GRCm39) |
S198P |
probably damaging |
Het |
| Tmprss11b |
C |
T |
5: 86,808,355 (GRCm39) |
R407H |
possibly damaging |
Het |
| Tspyl4 |
G |
A |
10: 34,174,107 (GRCm39) |
E200K |
probably damaging |
Het |
| Ttc21a |
T |
C |
9: 119,771,707 (GRCm39) |
Y169H |
probably damaging |
Het |
| Ugt2b36 |
C |
T |
5: 87,239,930 (GRCm39) |
D152N |
probably damaging |
Het |
| Unk |
T |
C |
11: 115,940,235 (GRCm39) |
I196T |
probably benign |
Het |
| Uroc1 |
T |
G |
6: 90,321,153 (GRCm39) |
V243G |
probably damaging |
Het |
| Usp34 |
C |
A |
11: 23,438,862 (GRCm39) |
Q3475K |
probably benign |
Het |
| Vmn2r117 |
T |
A |
17: 23,697,447 (GRCm39) |
I82L |
probably benign |
Het |
| Vmn2r44 |
A |
T |
7: 8,380,882 (GRCm39) |
V337E |
probably damaging |
Het |
| Zbtb14 |
C |
A |
17: 69,695,497 (GRCm39) |
F398L |
probably damaging |
Het |
| Zfp362 |
T |
C |
4: 128,680,993 (GRCm39) |
T111A |
probably benign |
Het |
| Zfp598 |
T |
C |
17: 24,899,046 (GRCm39) |
V615A |
probably benign |
Het |
|
| Other mutations in Cd109 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Cd109
|
APN |
9 |
78,524,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00465:Cd109
|
APN |
9 |
78,568,216 (GRCm39) |
nonsense |
probably null |
|
|
IGL00667:Cd109
|
APN |
9 |
78,592,159 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01432:Cd109
|
APN |
9 |
78,605,405 (GRCm39) |
missense |
probably benign |
|
|
IGL01795:Cd109
|
APN |
9 |
78,569,047 (GRCm39) |
splice site |
probably benign |
|
|
IGL02343:Cd109
|
APN |
9 |
78,596,237 (GRCm39) |
splice site |
probably benign |
|
|
IGL02450:Cd109
|
APN |
9 |
78,603,132 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL02699:Cd109
|
APN |
9 |
78,579,271 (GRCm39) |
splice site |
probably benign |
|
|
IGL02738:Cd109
|
APN |
9 |
78,598,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02797:Cd109
|
APN |
9 |
78,568,995 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03160:Cd109
|
APN |
9 |
78,568,338 (GRCm39) |
splice site |
probably null |
|
|
IGL03349:Cd109
|
APN |
9 |
78,543,767 (GRCm39) |
missense |
probably benign |
0.34 |
|
FR4589:Cd109
|
UTSW |
9 |
78,619,811 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R0048:Cd109
|
UTSW |
9 |
78,587,303 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R0060:Cd109
|
UTSW |
9 |
78,610,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0060:Cd109
|
UTSW |
9 |
78,610,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0158:Cd109
|
UTSW |
9 |
78,596,214 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R0415:Cd109
|
UTSW |
9 |
78,619,897 (GRCm39) |
missense |
probably benign |
0.13 |
|
R0659:Cd109
|
UTSW |
9 |
78,587,452 (GRCm39) |
splice site |
probably benign |
|
|
R0709:Cd109
|
UTSW |
9 |
78,579,260 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0840:Cd109
|
UTSW |
9 |
78,571,612 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0909:Cd109
|
UTSW |
9 |
78,543,755 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0945:Cd109
|
UTSW |
9 |
78,596,223 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1344:Cd109
|
UTSW |
9 |
78,579,832 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1484:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R1570:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R1688:Cd109
|
UTSW |
9 |
78,612,373 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1773:Cd109
|
UTSW |
9 |
78,611,006 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1813:Cd109
|
UTSW |
9 |
78,524,287 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2004:Cd109
|
UTSW |
9 |
78,611,044 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2083:Cd109
|
UTSW |
9 |
78,574,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2483:Cd109
|
UTSW |
9 |
78,574,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2857:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2858:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2859:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2911:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2912:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2914:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R2927:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3623:Cd109
|
UTSW |
9 |
78,574,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3713:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3760:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3762:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3771:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3772:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3773:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3916:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R3917:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4117:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4260:Cd109
|
UTSW |
9 |
78,543,745 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4387:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4389:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4526:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4527:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4528:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4700:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4708:Cd109
|
UTSW |
9 |
78,579,871 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4723:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4750:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4751:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4754:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4755:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4773:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R4984:Cd109
|
UTSW |
9 |
78,541,959 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5259:Cd109
|
UTSW |
9 |
78,617,434 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5353:Cd109
|
UTSW |
9 |
78,617,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5440:Cd109
|
UTSW |
9 |
78,587,446 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5559:Cd109
|
UTSW |
9 |
78,568,250 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5701:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R5995:Cd109
|
UTSW |
9 |
78,607,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5997:Cd109
|
UTSW |
9 |
78,612,344 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6103:Cd109
|
UTSW |
9 |
78,605,596 (GRCm39) |
splice site |
probably null |
|
|
R6174:Cd109
|
UTSW |
9 |
78,572,828 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6410:Cd109
|
UTSW |
9 |
78,564,798 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6529:Cd109
|
UTSW |
9 |
78,619,907 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6655:Cd109
|
UTSW |
9 |
78,592,220 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6704:Cd109
|
UTSW |
9 |
78,587,357 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6772:Cd109
|
UTSW |
9 |
78,588,092 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R6817:Cd109
|
UTSW |
9 |
78,622,237 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6903:Cd109
|
UTSW |
9 |
78,543,885 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7294:Cd109
|
UTSW |
9 |
78,619,917 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7432:Cd109
|
UTSW |
9 |
78,622,225 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7566:Cd109
|
UTSW |
9 |
78,588,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Cd109
|
UTSW |
9 |
78,617,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7986:Cd109
|
UTSW |
9 |
78,596,048 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8017:Cd109
|
UTSW |
9 |
78,614,828 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8019:Cd109
|
UTSW |
9 |
78,614,828 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8050:Cd109
|
UTSW |
9 |
78,571,633 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8225:Cd109
|
UTSW |
9 |
78,568,972 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8269:Cd109
|
UTSW |
9 |
78,572,964 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8479:Cd109
|
UTSW |
9 |
78,574,628 (GRCm39) |
nonsense |
probably null |
|
|
R8493:Cd109
|
UTSW |
9 |
78,564,801 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8781:Cd109
|
UTSW |
9 |
78,543,929 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8977:Cd109
|
UTSW |
9 |
78,614,810 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9051:Cd109
|
UTSW |
9 |
78,619,813 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R9051:Cd109
|
UTSW |
9 |
78,619,782 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
R9228:Cd109
|
UTSW |
9 |
78,577,042 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9366:Cd109
|
UTSW |
9 |
78,622,275 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9430:Cd109
|
UTSW |
9 |
78,574,698 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9572:Cd109
|
UTSW |
9 |
78,567,588 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9691:Cd109
|
UTSW |
9 |
78,611,074 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9736:Cd109
|
UTSW |
9 |
78,619,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9749:Cd109
|
UTSW |
9 |
78,592,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9751:Cd109
|
UTSW |
9 |
78,605,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9752:Cd109
|
UTSW |
9 |
78,614,834 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9789:Cd109
|
UTSW |
9 |
78,541,944 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9797:Cd109
|
UTSW |
9 |
78,579,217 (GRCm39) |
missense |
probably benign |
0.04 |
|
RF002:Cd109
|
UTSW |
9 |
78,619,810 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF002:Cd109
|
UTSW |
9 |
78,619,805 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF003:Cd109
|
UTSW |
9 |
78,619,813 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF011:Cd109
|
UTSW |
9 |
78,619,810 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF013:Cd109
|
UTSW |
9 |
78,619,813 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF047:Cd109
|
UTSW |
9 |
78,619,809 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
RF060:Cd109
|
UTSW |
9 |
78,619,807 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
Z1177:Cd109
|
UTSW |
9 |
78,598,595 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGAACTCTTCAGCCTAAGTTTTGTTTTGC -3'
(R):5'- ACCGTCTCCACTGTGTCAACCAA -3'
Sequencing Primer
(F):5'- cctctggaactgaaattaacagac -3'
(R):5'- GCATGTCTCTTGAAATTTTCTCATCT -3'
|
| Posted On |
2014-03-28 |
Incidental Mutation