Incidental Mutation 'R0401:Sbno1'
| ID |
38200 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Sbno1
|
| Ensembl Gene |
ENSMUSG00000038095 |
| Gene Name |
strawberry notch 1 |
| Synonyms |
9330180L10Rik, sno |
| MMRRC Submission |
038606-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0401 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
124506765-124564059 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 124548348 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 111
(T111I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143314
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000065263]
[ENSMUST00000168651]
[ENSMUST00000196329]
[ENSMUST00000196644]
[ENSMUST00000196711]
[ENSMUST00000197777]
[ENSMUST00000198420]
[ENSMUST00000199004]
[ENSMUST00000200474]
[ENSMUST00000199808]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000065263
AA Change: T111I
PolyPhen 2
Score 0.229 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000066808
Gene: ENSMUSG00000038095
AA Change: T111I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
254 |
559 |
3.6e-144 |
PFAM |
|
Pfam:ResIII
|
287 |
478 |
2.7e-8 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
3.6e-126 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168651
AA Change: T110I
PolyPhen 2
Score 0.229 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000130860
Gene: ENSMUSG00000038095
AA Change: T110I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
254 |
559 |
3.6e-144 |
PFAM |
|
Pfam:ResIII
|
287 |
478 |
2.7e-8 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
3.6e-126 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196329
AA Change: T76I
PolyPhen 2
Score 0.128 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000143084
Gene: ENSMUSG00000038095
AA Change: T76I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
182 |
199 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
217 |
525 |
1.4e-139 |
PFAM |
|
Pfam:ResIII
|
254 |
441 |
2.4e-8 |
PFAM |
|
low complexity region
|
598 |
614 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196644
AA Change: T111I
PolyPhen 2
Score 0.143 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000142827
Gene: ENSMUSG00000038095
AA Change: T111I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
252 |
560 |
4.3e-136 |
PFAM |
|
Pfam:ResIII
|
289 |
476 |
1.8e-6 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000196711
AA Change: T76I
PolyPhen 2
Score 0.924 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000142980
Gene: ENSMUSG00000038095
AA Change: T76I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
51 |
N/A |
INTRINSIC |
|
low complexity region
|
182 |
199 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000197777
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000198420
AA Change: T75I
PolyPhen 2
Score 0.877 (Sensitivity: 0.83; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000142416
Gene: ENSMUSG00000038095
AA Change: T75I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
50 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000199004
AA Change: T111I
PolyPhen 2
Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000143314
Gene: ENSMUSG00000038095
AA Change: T111I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200474
AA Change: T75I
PolyPhen 2
Score 0.064 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000143516
Gene: ENSMUSG00000038095
AA Change: T75I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
35 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
181 |
198 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
218 |
523 |
2.3e-141 |
PFAM |
|
Pfam:ResIII
|
251 |
442 |
3.3e-7 |
PFAM |
|
low complexity region
|
597 |
613 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
755 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199808
AA Change: T111I
PolyPhen 2
Score 0.229 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000142481
Gene: ENSMUSG00000038095
AA Change: T111I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
217 |
234 |
N/A |
INTRINSIC |
|
Pfam:AAA_34
|
252 |
560 |
6e-139 |
PFAM |
|
Pfam:ResIII
|
289 |
476 |
1.3e-7 |
PFAM |
|
low complexity region
|
633 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
727 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
797 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
838 |
N/A |
INTRINSIC |
|
coiled coil region
|
839 |
868 |
N/A |
INTRINSIC |
|
Pfam:Helicase_C_4
|
870 |
1146 |
4.6e-120 |
PFAM |
|
low complexity region
|
1365 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200674
|
| Meta Mutation Damage Score |
0.1025 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.6%
|
| Validation Efficiency |
98% (90/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
T |
3: 137,776,067 (GRCm39) |
H1752L |
possibly damaging |
Het |
| Abcc5 |
T |
C |
16: 20,195,308 (GRCm39) |
K730E |
probably benign |
Het |
| Ahnak |
A |
G |
19: 8,992,480 (GRCm39) |
D4588G |
probably benign |
Het |
| AI467606 |
G |
A |
7: 126,691,608 (GRCm39) |
R61H |
probably damaging |
Het |
| Apoa4 |
T |
A |
9: 46,154,356 (GRCm39) |
V319E |
probably damaging |
Het |
| Ark2n |
C |
A |
18: 77,761,658 (GRCm39) |
S218I |
probably damaging |
Het |
| Atad5 |
T |
A |
11: 80,011,525 (GRCm39) |
D1297E |
probably benign |
Het |
| BC005624 |
G |
A |
2: 30,870,021 (GRCm39) |
T62I |
probably benign |
Het |
| Bcl6 |
T |
C |
16: 23,791,344 (GRCm39) |
K337E |
probably damaging |
Het |
| Cad |
T |
A |
5: 31,231,330 (GRCm39) |
|
probably benign |
Het |
| Ccdc73 |
T |
C |
2: 104,821,634 (GRCm39) |
S528P |
probably benign |
Het |
| Ccng2 |
T |
G |
5: 93,421,272 (GRCm39) |
C261G |
possibly damaging |
Het |
| Cdh11 |
A |
T |
8: 103,400,638 (GRCm39) |
I110N |
probably damaging |
Het |
| Cgnl1 |
A |
G |
9: 71,612,521 (GRCm39) |
V767A |
probably damaging |
Het |
| Cit |
A |
G |
5: 116,123,538 (GRCm39) |
T1460A |
probably benign |
Het |
| Clec4b2 |
C |
T |
6: 123,158,259 (GRCm39) |
Q42* |
probably null |
Het |
| Clip1 |
A |
G |
5: 123,791,852 (GRCm39) |
V106A |
probably damaging |
Het |
| Crb1 |
T |
C |
1: 139,126,529 (GRCm39) |
|
probably benign |
Het |
| Cts6 |
T |
C |
13: 61,346,153 (GRCm39) |
|
probably benign |
Het |
| Cul9 |
T |
C |
17: 46,852,630 (GRCm39) |
E244G |
probably damaging |
Het |
| Dcaf8l |
C |
A |
X: 88,448,815 (GRCm39) |
R438L |
probably benign |
Het |
| Ddx55 |
A |
T |
5: 124,706,014 (GRCm39) |
I480F |
probably damaging |
Het |
| Dixdc1 |
A |
G |
9: 50,604,974 (GRCm39) |
S17P |
possibly damaging |
Het |
| Drosha |
T |
A |
15: 12,926,117 (GRCm39) |
Y1235* |
probably null |
Het |
| Dsg2 |
G |
T |
18: 20,725,565 (GRCm39) |
|
probably benign |
Het |
| E2f5 |
T |
C |
3: 14,644,085 (GRCm39) |
|
probably null |
Het |
| Epc2 |
A |
G |
2: 49,418,986 (GRCm39) |
T265A |
probably damaging |
Het |
| Etaa1 |
T |
G |
11: 17,897,514 (GRCm39) |
D201A |
probably damaging |
Het |
| Fancd2 |
T |
C |
6: 113,525,304 (GRCm39) |
I260T |
possibly damaging |
Het |
| Fhdc1 |
G |
A |
3: 84,351,931 (GRCm39) |
A1098V |
probably benign |
Het |
| Gpd2 |
G |
A |
2: 57,230,105 (GRCm39) |
V286I |
possibly damaging |
Het |
| Gpr141b |
A |
T |
13: 19,913,664 (GRCm39) |
|
noncoding transcript |
Het |
| H2-T9 |
C |
T |
17: 36,439,597 (GRCm39) |
V128M |
probably damaging |
Het |
| Herc2 |
A |
C |
7: 55,807,480 (GRCm39) |
E2523A |
probably damaging |
Het |
| Irag1 |
G |
A |
7: 110,476,104 (GRCm39) |
P757S |
probably benign |
Het |
| Jmjd1c |
G |
A |
10: 67,056,161 (GRCm39) |
R527H |
probably damaging |
Het |
| Kif12 |
G |
A |
4: 63,087,762 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,309,492 (GRCm39) |
N2802K |
probably damaging |
Het |
| Mab21l2 |
C |
G |
3: 86,454,296 (GRCm39) |
G235R |
probably benign |
Het |
| Mapk8 |
T |
C |
14: 33,104,165 (GRCm39) |
E417G |
probably benign |
Het |
| Mapk8ip3 |
G |
A |
17: 25,128,145 (GRCm39) |
|
probably benign |
Het |
| Mettl1 |
A |
G |
10: 126,880,946 (GRCm39) |
T203A |
probably benign |
Het |
| Mettl9 |
T |
C |
7: 120,675,536 (GRCm39) |
V312A |
probably damaging |
Het |
| Mex3d |
A |
G |
10: 80,222,728 (GRCm39) |
V176A |
probably benign |
Het |
| Mmp3 |
T |
C |
9: 7,449,790 (GRCm39) |
S225P |
probably damaging |
Het |
| Neb |
G |
A |
2: 52,078,689 (GRCm39) |
|
probably benign |
Het |
| Ninj2 |
C |
T |
6: 120,175,012 (GRCm39) |
A51V |
possibly damaging |
Het |
| Nle1 |
A |
G |
11: 82,796,205 (GRCm39) |
|
probably benign |
Het |
| Nol9 |
T |
C |
4: 152,137,062 (GRCm39) |
Y532H |
probably benign |
Het |
| Nr2c1 |
T |
A |
10: 94,007,020 (GRCm39) |
V286E |
probably benign |
Het |
| Or4b1b |
A |
T |
2: 90,112,748 (GRCm39) |
M57K |
probably damaging |
Het |
| Or4c31 |
T |
G |
2: 88,292,269 (GRCm39) |
L195R |
probably damaging |
Het |
| Or52e18 |
T |
A |
7: 104,609,150 (GRCm39) |
H263L |
probably damaging |
Het |
| Or5p4 |
T |
A |
7: 107,680,079 (GRCm39) |
I26N |
possibly damaging |
Het |
| Or6c69 |
A |
G |
10: 129,747,785 (GRCm39) |
Y121H |
probably benign |
Het |
| Or6f1 |
T |
C |
7: 85,970,500 (GRCm39) |
Y220C |
probably benign |
Het |
| Or9k7 |
A |
G |
10: 130,046,489 (GRCm39) |
L170P |
probably damaging |
Het |
| Ovch2 |
A |
T |
7: 107,400,343 (GRCm39) |
V15D |
probably damaging |
Het |
| Pate8 |
G |
T |
9: 36,493,924 (GRCm39) |
A3E |
unknown |
Het |
| Pclo |
T |
G |
5: 14,731,748 (GRCm39) |
S3417A |
unknown |
Het |
| Pex1 |
T |
A |
5: 3,683,759 (GRCm39) |
M1085K |
probably damaging |
Het |
| Plscr2 |
T |
C |
9: 92,164,188 (GRCm39) |
S6P |
probably benign |
Het |
| Pogz |
C |
T |
3: 94,784,336 (GRCm39) |
P722S |
possibly damaging |
Het |
| Pom121l2 |
A |
T |
13: 22,166,395 (GRCm39) |
D222V |
probably benign |
Het |
| Prpf40a |
T |
C |
2: 53,049,325 (GRCm39) |
Y179C |
probably damaging |
Het |
| R3hdm2 |
A |
G |
10: 127,294,042 (GRCm39) |
I179V |
possibly damaging |
Het |
| Ranbp9 |
A |
C |
13: 43,576,134 (GRCm39) |
V355G |
probably damaging |
Het |
| Rims2 |
T |
C |
15: 39,373,028 (GRCm39) |
|
probably benign |
Het |
| Ryr2 |
A |
T |
13: 11,720,570 (GRCm39) |
S2693T |
probably benign |
Het |
| Sdk1 |
A |
C |
5: 142,031,916 (GRCm39) |
N997T |
possibly damaging |
Het |
| Setx |
G |
T |
2: 29,056,301 (GRCm39) |
E39* |
probably null |
Het |
| Skint7 |
T |
A |
4: 111,837,559 (GRCm39) |
N112K |
probably damaging |
Het |
| Slc35e1 |
T |
C |
8: 73,246,415 (GRCm39) |
|
probably benign |
Het |
| Slc4a10 |
A |
T |
2: 62,021,192 (GRCm39) |
D80V |
probably benign |
Het |
| Susd2 |
C |
A |
10: 75,474,437 (GRCm39) |
|
probably benign |
Het |
| Tcam1 |
G |
A |
11: 106,174,904 (GRCm39) |
E120K |
probably benign |
Het |
| Tcf3 |
G |
T |
10: 80,256,992 (GRCm39) |
S77R |
probably damaging |
Het |
| Tdpoz3 |
T |
C |
3: 93,733,672 (GRCm39) |
Y116H |
probably benign |
Het |
| Tex26 |
C |
A |
5: 149,384,323 (GRCm39) |
D164E |
probably benign |
Het |
| Thoc5 |
G |
A |
11: 4,852,213 (GRCm39) |
|
probably benign |
Het |
| Tiparp |
A |
G |
3: 65,438,857 (GRCm39) |
R58G |
probably benign |
Het |
| Trim66 |
A |
T |
7: 109,074,471 (GRCm39) |
C597S |
probably damaging |
Het |
| Ugt2a3 |
T |
A |
5: 87,484,349 (GRCm39) |
Q225L |
probably benign |
Het |
| Vmn1r25 |
T |
A |
6: 57,955,696 (GRCm39) |
I198L |
probably benign |
Het |
| Vmn2r106 |
A |
T |
17: 20,499,281 (GRCm39) |
V210D |
possibly damaging |
Het |
| Vmn2r124 |
T |
C |
17: 18,284,407 (GRCm39) |
F483L |
probably damaging |
Het |
| Vmn2r78 |
A |
G |
7: 86,570,519 (GRCm39) |
K346E |
probably benign |
Het |
| Zfhx4 |
T |
A |
3: 5,466,221 (GRCm39) |
S2126R |
possibly damaging |
Het |
| Zfp608 |
C |
T |
18: 55,032,066 (GRCm39) |
G625R |
probably benign |
Het |
| Zkscan5 |
A |
G |
5: 145,149,385 (GRCm39) |
D234G |
probably damaging |
Het |
| Zscan10 |
T |
A |
17: 23,824,889 (GRCm39) |
V115E |
probably damaging |
Het |
|
| Other mutations in Sbno1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00563:Sbno1
|
APN |
5 |
124,540,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Sbno1
|
APN |
5 |
124,548,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01309:Sbno1
|
APN |
5 |
124,519,769 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL01330:Sbno1
|
APN |
5 |
124,530,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01541:Sbno1
|
APN |
5 |
124,516,618 (GRCm39) |
splice site |
probably benign |
|
|
IGL01800:Sbno1
|
APN |
5 |
124,519,568 (GRCm39) |
splice site |
probably benign |
|
|
IGL01987:Sbno1
|
APN |
5 |
124,542,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02178:Sbno1
|
APN |
5 |
124,538,258 (GRCm39) |
splice site |
probably null |
|
|
IGL02544:Sbno1
|
APN |
5 |
124,542,046 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02572:Sbno1
|
APN |
5 |
124,519,740 (GRCm39) |
splice site |
probably benign |
|
|
IGL02592:Sbno1
|
APN |
5 |
124,538,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03033:Sbno1
|
APN |
5 |
124,514,213 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03089:Sbno1
|
APN |
5 |
124,525,374 (GRCm39) |
splice site |
probably benign |
|
|
IGL03131:Sbno1
|
APN |
5 |
124,526,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Decrement
|
UTSW |
5 |
124,538,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0200:Sbno1
|
UTSW |
5 |
124,522,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0217:Sbno1
|
UTSW |
5 |
124,542,387 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0233:Sbno1
|
UTSW |
5 |
124,514,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0233:Sbno1
|
UTSW |
5 |
124,514,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0334:Sbno1
|
UTSW |
5 |
124,524,931 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0608:Sbno1
|
UTSW |
5 |
124,522,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0615:Sbno1
|
UTSW |
5 |
124,548,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Sbno1
|
UTSW |
5 |
124,524,955 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0655:Sbno1
|
UTSW |
5 |
124,514,212 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1037:Sbno1
|
UTSW |
5 |
124,531,975 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1439:Sbno1
|
UTSW |
5 |
124,522,523 (GRCm39) |
splice site |
probably benign |
|
|
R1522:Sbno1
|
UTSW |
5 |
124,530,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1590:Sbno1
|
UTSW |
5 |
124,522,567 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1618:Sbno1
|
UTSW |
5 |
124,542,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1671:Sbno1
|
UTSW |
5 |
124,530,130 (GRCm39) |
splice site |
probably null |
|
|
R1779:Sbno1
|
UTSW |
5 |
124,526,580 (GRCm39) |
unclassified |
probably benign |
|
|
R2103:Sbno1
|
UTSW |
5 |
124,532,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2136:Sbno1
|
UTSW |
5 |
124,525,597 (GRCm39) |
splice site |
probably null |
|
|
R2149:Sbno1
|
UTSW |
5 |
124,540,182 (GRCm39) |
splice site |
probably null |
|
|
R2153:Sbno1
|
UTSW |
5 |
124,516,606 (GRCm39) |
missense |
probably benign |
|
|
R2154:Sbno1
|
UTSW |
5 |
124,516,574 (GRCm39) |
missense |
probably benign |
|
|
R2231:Sbno1
|
UTSW |
5 |
124,543,767 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2879:Sbno1
|
UTSW |
5 |
124,526,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3004:Sbno1
|
UTSW |
5 |
124,519,771 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3922:Sbno1
|
UTSW |
5 |
124,519,993 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4061:Sbno1
|
UTSW |
5 |
124,526,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4096:Sbno1
|
UTSW |
5 |
124,529,983 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4612:Sbno1
|
UTSW |
5 |
124,542,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4879:Sbno1
|
UTSW |
5 |
124,542,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4937:Sbno1
|
UTSW |
5 |
124,512,672 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4990:Sbno1
|
UTSW |
5 |
124,538,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5341:Sbno1
|
UTSW |
5 |
124,546,538 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5365:Sbno1
|
UTSW |
5 |
124,519,929 (GRCm39) |
frame shift |
probably null |
|
|
R5399:Sbno1
|
UTSW |
5 |
124,530,804 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5704:Sbno1
|
UTSW |
5 |
124,533,956 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5898:Sbno1
|
UTSW |
5 |
124,524,854 (GRCm39) |
intron |
probably benign |
|
|
R6136:Sbno1
|
UTSW |
5 |
124,516,554 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6154:Sbno1
|
UTSW |
5 |
124,516,542 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6412:Sbno1
|
UTSW |
5 |
124,530,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6414:Sbno1
|
UTSW |
5 |
124,533,994 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6454:Sbno1
|
UTSW |
5 |
124,538,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7085:Sbno1
|
UTSW |
5 |
124,519,783 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7176:Sbno1
|
UTSW |
5 |
124,530,944 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7219:Sbno1
|
UTSW |
5 |
124,543,722 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7535:Sbno1
|
UTSW |
5 |
124,551,342 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7673:Sbno1
|
UTSW |
5 |
124,551,279 (GRCm39) |
missense |
probably benign |
|
|
R7692:Sbno1
|
UTSW |
5 |
124,543,709 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7745:Sbno1
|
UTSW |
5 |
124,530,962 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7762:Sbno1
|
UTSW |
5 |
124,512,729 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8012:Sbno1
|
UTSW |
5 |
124,522,565 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8142:Sbno1
|
UTSW |
5 |
124,546,608 (GRCm39) |
missense |
probably benign |
|
|
R8164:Sbno1
|
UTSW |
5 |
124,512,684 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8259:Sbno1
|
UTSW |
5 |
124,519,759 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8289:Sbno1
|
UTSW |
5 |
124,542,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Sbno1
|
UTSW |
5 |
124,512,618 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9045:Sbno1
|
UTSW |
5 |
124,543,720 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9149:Sbno1
|
UTSW |
5 |
124,519,762 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9529:Sbno1
|
UTSW |
5 |
124,517,413 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Sbno1
|
UTSW |
5 |
124,542,367 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1088:Sbno1
|
UTSW |
5 |
124,532,021 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGCTGAAAATGGACTTACTAGCTGC -3'
(R):5'- ACGTGAGCTTTGACTGCCTGAC -3'
Sequencing Primer
(F):5'- AATATTGGCGGGTGGCTTC -3'
(R):5'- ACAGTCAGCACCTTTCTGAG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation