Mutagenetix > Incidental Mutation

Incidental Mutation 'R1472:Nav3'

165016

Institutional Source

Beutler Lab

Gene Symbol

Nav3

Ensembl Gene

ENSMUSG00000020181

Gene Name

neuron navigator 3

Synonyms

Pomfil1p, 9630020C08Rik, POMFIL1, steerin 3, 4732483H20Rik, unc53H3

MMRRC Submission

039525-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1472 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

109517120-110292065 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 109563802 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 1627 (E1627G)

Ref Sequence

ENSEMBL: ENSMUSP00000032719 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032719]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000032719
AA Change: E1627G

PolyPhen 2 Score 0.991 (Sensitivity: 0.71; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000032719
Gene: ENSMUSG00000020181
AA Change: E1627G

Domain	Start	End	E-Value	Type
CH	79	182	4.41e-12	SMART
low complexity region	184	194	N/A	INTRINSIC
low complexity region	318	329	N/A	INTRINSIC
low complexity region	353	363	N/A	INTRINSIC
low complexity region	427	439	N/A	INTRINSIC
low complexity region	522	536	N/A	INTRINSIC
low complexity region	713	724	N/A	INTRINSIC
low complexity region	807	818	N/A	INTRINSIC
low complexity region	873	896	N/A	INTRINSIC
low complexity region	904	916	N/A	INTRINSIC
low complexity region	1077	1095	N/A	INTRINSIC
low complexity region	1160	1173	N/A	INTRINSIC
low complexity region	1207	1229	N/A	INTRINSIC
low complexity region	1256	1266	N/A	INTRINSIC
low complexity region	1274	1285	N/A	INTRINSIC
low complexity region	1293	1312	N/A	INTRINSIC
low complexity region	1327	1341	N/A	INTRINSIC
low complexity region	1383	1397	N/A	INTRINSIC
low complexity region	1462	1474	N/A	INTRINSIC
low complexity region	1550	1563	N/A	INTRINSIC
coiled coil region	1565	1656	N/A	INTRINSIC
low complexity region	1675	1692	N/A	INTRINSIC
low complexity region	1722	1733	N/A	INTRINSIC
low complexity region	1756	1781	N/A	INTRINSIC
low complexity region	1782	1795	N/A	INTRINSIC
coiled coil region	1801	1842	N/A	INTRINSIC
low complexity region	1848	1871	N/A	INTRINSIC
AAA	2029	2184	4.94e-7	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161223

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000161582

SMART Domains

Protein: ENSMUSP00000124591
Gene: ENSMUSG00000020181

Domain	Start	End	E-Value	Type
low complexity region	84	95	N/A	INTRINSIC
low complexity region	150	173	N/A	INTRINSIC
low complexity region	181	193	N/A	INTRINSIC
low complexity region	354	372	N/A	INTRINSIC
low complexity region	437	450	N/A	INTRINSIC
low complexity region	484	506	N/A	INTRINSIC
low complexity region	533	543	N/A	INTRINSIC
low complexity region	551	562	N/A	INTRINSIC
low complexity region	570	589	N/A	INTRINSIC
low complexity region	604	618	N/A	INTRINSIC
low complexity region	660	674	N/A	INTRINSIC
low complexity region	739	751	N/A	INTRINSIC
low complexity region	827	840	N/A	INTRINSIC
coiled coil region	842	933	N/A	INTRINSIC
low complexity region	952	969	N/A	INTRINSIC
low complexity region	992	1003	N/A	INTRINSIC
low complexity region	1026	1051	N/A	INTRINSIC
low complexity region	1052	1065	N/A	INTRINSIC
coiled coil region	1071	1112	N/A	INTRINSIC
low complexity region	1118	1141	N/A	INTRINSIC
AAA	1299	1454	4.94e-7	SMART

Coding Region Coverage

1x: 99.1%
3x: 98.2%
10x: 96.0%
20x: 92.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 84 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110002E22Rik	C	T	3: 137,773,313 (GRCm39)	T834M	possibly damaging	Het
Ak1	T	C	2: 32,520,313 (GRCm39)	L32P	probably damaging	Het
Ankrd24	A	G	10: 81,470,754 (GRCm39)	D61G	probably damaging	Het
Atp13a2	T	C	4: 140,721,113 (GRCm39)	S99P	probably damaging	Het
Atp8a2	T	C	14: 60,097,719 (GRCm39)	K770E	probably benign	Het
Bmp10	A	G	6: 87,410,779 (GRCm39)	I191V	probably benign	Het
C2cd6	A	T	1: 59,106,944 (GRCm39)	S294T	possibly damaging	Het
C4b	T	A	17: 34,962,743 (GRCm39)	K20*	probably null	Het
Caps2	C	T	10: 112,015,377 (GRCm39)	T139I	probably benign	Het
Cdc25a	T	C	9: 109,705,157 (GRCm39)	S34P	probably benign	Het
Cenpv	T	C	11: 62,427,121 (GRCm39)	I146V	probably benign	Het
Cep57	A	T	9: 13,732,850 (GRCm39)	F32I	probably benign	Het
Cep85	A	G	4: 133,894,711 (GRCm39)	W32R	probably damaging	Het
Cntrl	T	C	2: 35,059,329 (GRCm39)		probably null	Het
Cpd	A	G	11: 76,675,224 (GRCm39)	V1299A	probably damaging	Het
Cpne6	T	C	14: 55,752,092 (GRCm39)	V283A	probably benign	Het
Crot	A	G	5: 9,016,941 (GRCm39)	C584R	probably damaging	Het
Ctsc	A	C	7: 87,930,670 (GRCm39)	H83P	possibly damaging	Het
Dido1	T	C	2: 180,302,513 (GRCm39)	N1797S	probably benign	Het
Dlgap4	C	T	2: 156,602,821 (GRCm39)	Q148*	probably null	Het
Dnah3	T	C	7: 119,670,181 (GRCm39)	D688G	probably benign	Het
Dnmt1	T	C	9: 20,843,472 (GRCm39)	E138G	probably benign	Het
Edc4	T	A	8: 106,619,460 (GRCm39)	M1396K	probably damaging	Het
Haao	T	A	17: 84,146,267 (GRCm39)	Q69L	probably benign	Het
Hsd3b6	A	T	3: 98,715,255 (GRCm39)		probably null	Het
Itpr3	T	A	17: 27,333,199 (GRCm39)	I1937N	probably benign	Het
Kcnk15	C	A	2: 163,700,127 (GRCm39)	T103K	probably damaging	Het
Kifc3	A	G	8: 95,864,541 (GRCm39)		probably null	Het
Lama3	T	A	18: 12,615,102 (GRCm39)	F1342Y	probably benign	Het
Lilra6	A	T	7: 3,915,718 (GRCm39)	M98K	probably damaging	Het
Map3k21	T	C	8: 126,668,417 (GRCm39)	S668P	probably benign	Het
Mcpt8	T	C	14: 56,319,791 (GRCm39)	T220A	probably benign	Het
Mettl13	C	T	1: 162,364,736 (GRCm39)	V548I	possibly damaging	Het
Mfsd4b4	A	G	10: 39,767,860 (GRCm39)	M411T	probably benign	Het
Mrfap1	A	G	5: 36,953,817 (GRCm39)	S41P	possibly damaging	Het
Mroh2b	A	G	15: 4,978,137 (GRCm39)	I1302V	probably benign	Het
Mrpl45	C	T	11: 97,214,681 (GRCm39)	R123*	probably null	Het
Mstn	T	A	1: 53,101,157 (GRCm39)	I78K	probably damaging	Het
Mtdh	T	C	15: 34,114,191 (GRCm39)	S168P	possibly damaging	Het
Muc15	G	T	2: 110,561,905 (GRCm39)	V114F	probably damaging	Het
Muc6	T	C	7: 141,238,144 (GRCm39)	E112G	probably benign	Het
Myocd	G	T	11: 65,078,330 (GRCm39)	H360Q	probably benign	Het
Naip2	C	T	13: 100,298,368 (GRCm39)	G556D	probably benign	Het
Nlrp14	T	C	7: 106,781,910 (GRCm39)	L369P	probably benign	Het
Nlrp6	A	G	7: 140,503,408 (GRCm39)	T505A	probably damaging	Het
Npbwr1	T	C	1: 5,986,900 (GRCm39)	S205G	probably damaging	Het
Nsmaf	G	A	4: 6,423,448 (GRCm39)	R307*	probably null	Het
Or5h19	A	T	16: 58,856,920 (GRCm39)	L60Q	probably damaging	Het
Or9i1b	T	C	19: 13,897,208 (GRCm39)	S275P	probably damaging	Het
Parp9	T	G	16: 35,774,050 (GRCm39)	S341A	possibly damaging	Het
Pdss2	A	G	10: 43,289,533 (GRCm39)	N346S	probably benign	Het
Pikfyve	T	A	1: 65,263,360 (GRCm39)	F503Y	probably damaging	Het
Polr1e	G	T	4: 45,028,026 (GRCm39)	A290S	probably damaging	Het
Ppp1r21	A	T	17: 88,866,033 (GRCm39)	H305L	probably damaging	Het
Prss47	A	G	13: 65,197,103 (GRCm39)	L117P	probably damaging	Het
Psmb2	A	G	4: 126,580,825 (GRCm39)	Y73C	probably damaging	Het
Rcn2	C	T	9: 55,963,537 (GRCm39)	P222L	probably benign	Het
Rnf144b	T	C	13: 47,396,361 (GRCm39)	Y233H	probably damaging	Het
Rnf17	T	C	14: 56,665,436 (GRCm39)	L196P	probably damaging	Het
Sik2	A	G	9: 50,920,111 (GRCm39)	I22T	probably damaging	Het
Sis	A	G	3: 72,796,360 (GRCm39)	V1807A	probably benign	Het
Slc1a2	T	A	2: 102,568,254 (GRCm39)	I88N	probably damaging	Het
Slc22a22	A	G	15: 57,110,916 (GRCm39)	F437S	probably benign	Het
Slc39a13	A	T	2: 90,899,050 (GRCm39)	C20*	probably null	Het
Sos2	C	T	12: 69,632,090 (GRCm39)		probably null	Het
Sst	A	G	16: 23,709,448 (GRCm39)	V16A	probably benign	Het
Stab1	C	T	14: 30,863,543 (GRCm39)	G2073D	probably benign	Het
Stxbp1	A	T	2: 32,684,648 (GRCm39)	S594T	probably benign	Het
Sugct	A	T	13: 17,627,131 (GRCm39)	C241S	probably benign	Het
Svil	T	A	18: 5,048,950 (GRCm39)	C76S	probably benign	Het
Tcaf1	A	G	6: 42,663,382 (GRCm39)	V166A	possibly damaging	Het
Tmem131	A	T	1: 36,855,322 (GRCm39)	N801K	possibly damaging	Het
Tox3	T	C	8: 90,980,973 (GRCm39)	N277S	probably damaging	Het
Tril	G	T	6: 53,795,012 (GRCm39)	R737S	probably damaging	Het
Trpm2	C	A	10: 77,801,841 (GRCm39)	V75L	probably damaging	Het
Tshz1	A	C	18: 84,031,930 (GRCm39)	L826R	possibly damaging	Het
Ttn	C	T	2: 76,597,196 (GRCm39)	V19906I	probably damaging	Het
Wnt5a	C	T	14: 28,240,461 (GRCm39)	R184*	probably null	Het
Wnt5b	G	A	6: 119,410,442 (GRCm39)	R333C	probably damaging	Het
Zbtb6	T	C	2: 37,319,356 (GRCm39)	T191A	probably benign	Het
Zc3h4	A	G	7: 16,168,695 (GRCm39)	N935D	unknown	Het
Zc3h7a	C	T	16: 10,978,890 (GRCm39)	R95H	probably damaging	Het
Zfp110	T	C	7: 12,582,468 (GRCm39)	V372A	possibly damaging	Het
Zmym2	C	T	14: 57,148,640 (GRCm39)	S318L	probably benign	Het

Other mutations in Nav3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00095:Nav3	APN	10	109,677,594 (GRCm39)	missense	probably damaging	0.99
IGL00425:Nav3	APN	10	109,539,368 (GRCm39)	missense	probably benign	0.13
IGL00465:Nav3	APN	10	109,688,607 (GRCm39)	missense	probably damaging	0.99
IGL00531:Nav3	APN	10	109,539,171 (GRCm39)	missense	probably null	0.99
IGL00575:Nav3	APN	10	109,600,626 (GRCm39)	missense	probably damaging	0.98
IGL00770:Nav3	APN	10	109,652,124 (GRCm39)	missense	probably damaging	1.00
IGL00774:Nav3	APN	10	109,652,124 (GRCm39)	missense	probably damaging	1.00
IGL00858:Nav3	APN	10	109,578,493 (GRCm39)	missense	probably damaging	0.98
IGL00935:Nav3	APN	10	109,541,527 (GRCm39)	missense	probably benign
IGL01638:Nav3	APN	10	109,688,724 (GRCm39)	missense	probably damaging	1.00
IGL01662:Nav3	APN	10	109,605,119 (GRCm39)	missense	possibly damaging	0.56
IGL01670:Nav3	APN	10	109,550,102 (GRCm39)	missense	possibly damaging	0.92
IGL01885:Nav3	APN	10	109,578,521 (GRCm39)	nonsense	probably null
IGL01979:Nav3	APN	10	109,540,790 (GRCm39)	missense	probably benign	0.01
IGL02121:Nav3	APN	10	109,594,897 (GRCm39)	missense	probably damaging	0.99
IGL02210:Nav3	APN	10	109,602,851 (GRCm39)	missense	probably benign
IGL02523:Nav3	APN	10	109,605,157 (GRCm39)	missense	probably damaging	1.00
IGL02573:Nav3	APN	10	109,702,835 (GRCm39)	missense	probably benign	0.23
IGL02633:Nav3	APN	10	109,527,997 (GRCm39)	missense	probably benign	0.09
IGL02810:Nav3	APN	10	109,652,135 (GRCm39)	missense	probably damaging	1.00
IGL02964:Nav3	APN	10	109,572,814 (GRCm39)	missense	probably damaging	0.99
IGL03015:Nav3	APN	10	109,554,158 (GRCm39)	missense	probably damaging	0.98
IGL03288:Nav3	APN	10	109,594,878 (GRCm39)	missense	probably damaging	1.00
IGL03310:Nav3	APN	10	109,660,433 (GRCm39)	critical splice donor site	probably null
PIT4377001:Nav3	UTSW	10	109,552,466 (GRCm39)	missense	probably damaging	0.99
R0010:Nav3	UTSW	10	109,659,087 (GRCm39)	splice site	probably benign
R0043:Nav3	UTSW	10	109,603,379 (GRCm39)	missense	possibly damaging	0.95
R0053:Nav3	UTSW	10	109,602,778 (GRCm39)	splice site	probably benign
R0053:Nav3	UTSW	10	109,602,778 (GRCm39)	splice site	probably benign
R0077:Nav3	UTSW	10	109,552,503 (GRCm39)	missense	possibly damaging	0.87
R0219:Nav3	UTSW	10	109,702,791 (GRCm39)	critical splice donor site	probably null
R0310:Nav3	UTSW	10	109,602,989 (GRCm39)	missense	possibly damaging	0.82
R0380:Nav3	UTSW	10	109,594,740 (GRCm39)	splice site	probably benign
R0403:Nav3	UTSW	10	109,602,964 (GRCm39)	missense	probably damaging	0.98
R0480:Nav3	UTSW	10	109,689,161 (GRCm39)	missense	probably damaging	1.00
R0626:Nav3	UTSW	10	109,659,325 (GRCm39)	missense	probably damaging	1.00
R0637:Nav3	UTSW	10	109,606,058 (GRCm39)	missense	probably benign	0.25
R0847:Nav3	UTSW	10	109,739,718 (GRCm39)	missense	possibly damaging	0.94
R0988:Nav3	UTSW	10	109,552,389 (GRCm39)	missense	probably damaging	1.00
R1272:Nav3	UTSW	10	109,572,860 (GRCm39)	missense	probably damaging	0.98
R1295:Nav3	UTSW	10	109,527,963 (GRCm39)	missense	probably damaging	1.00
R1405:Nav3	UTSW	10	109,606,194 (GRCm39)	splice site	probably benign
R1406:Nav3	UTSW	10	109,719,495 (GRCm39)	missense	possibly damaging	0.64
R1406:Nav3	UTSW	10	109,719,495 (GRCm39)	missense	possibly damaging	0.64
R1420:Nav3	UTSW	10	109,659,115 (GRCm39)	missense	probably benign	0.02
R1449:Nav3	UTSW	10	109,689,372 (GRCm39)	missense	probably benign	0.13
R1458:Nav3	UTSW	10	109,555,905 (GRCm39)	missense	probably damaging	1.00
R1469:Nav3	UTSW	10	109,596,369 (GRCm39)	missense	probably damaging	1.00
R1469:Nav3	UTSW	10	109,596,369 (GRCm39)	missense	probably damaging	1.00
R1537:Nav3	UTSW	10	109,702,846 (GRCm39)	missense	probably damaging	1.00
R1539:Nav3	UTSW	10	109,603,031 (GRCm39)	missense	probably damaging	0.99
R1581:Nav3	UTSW	10	109,659,289 (GRCm39)	missense	probably damaging	1.00
R1586:Nav3	UTSW	10	109,689,115 (GRCm39)	missense	probably damaging	1.00
R1654:Nav3	UTSW	10	109,688,984 (GRCm39)	missense	possibly damaging	0.85
R1725:Nav3	UTSW	10	109,659,451 (GRCm39)	missense	probably damaging	1.00
R1742:Nav3	UTSW	10	109,605,074 (GRCm39)	missense	probably benign
R1793:Nav3	UTSW	10	109,539,233 (GRCm39)	missense	probably benign	0.00
R1830:Nav3	UTSW	10	109,659,184 (GRCm39)	missense	probably damaging	1.00
R1834:Nav3	UTSW	10	109,555,883 (GRCm39)	missense	probably damaging	0.99
R1881:Nav3	UTSW	10	109,688,420 (GRCm39)	missense	probably damaging	0.96
R1922:Nav3	UTSW	10	109,541,467 (GRCm39)	missense	probably benign	0.43
R1944:Nav3	UTSW	10	109,552,391 (GRCm39)	missense	probably damaging	0.99
R1981:Nav3	UTSW	10	109,554,951 (GRCm39)	splice site	probably benign
R1985:Nav3	UTSW	10	109,606,045 (GRCm39)	splice site	probably benign
R1996:Nav3	UTSW	10	109,689,262 (GRCm39)	missense	probably damaging	1.00
R2051:Nav3	UTSW	10	109,660,536 (GRCm39)	missense	probably damaging	0.99
R2062:Nav3	UTSW	10	109,555,882 (GRCm39)	missense	probably damaging	1.00
R2139:Nav3	UTSW	10	109,688,996 (GRCm39)	missense	probably benign	0.22
R2248:Nav3	UTSW	10	109,532,088 (GRCm39)	missense	probably damaging	1.00
R2420:Nav3	UTSW	10	109,699,674 (GRCm39)	missense	probably damaging	0.98
R2444:Nav3	UTSW	10	109,600,776 (GRCm39)	missense	probably benign	0.09
R3026:Nav3	UTSW	10	109,660,465 (GRCm39)	missense	probably damaging	0.99
R3052:Nav3	UTSW	10	109,739,613 (GRCm39)	missense	probably damaging	0.99
R3441:Nav3	UTSW	10	109,540,789 (GRCm39)	missense	probably benign	0.01
R3845:Nav3	UTSW	10	109,689,237 (GRCm39)	missense	possibly damaging	0.82
R3929:Nav3	UTSW	10	109,520,064 (GRCm39)	missense	probably damaging	1.00
R3932:Nav3	UTSW	10	109,529,896 (GRCm39)	missense	probably damaging	0.99
R4056:Nav3	UTSW	10	109,716,394 (GRCm39)	critical splice donor site	probably null
R4057:Nav3	UTSW	10	109,716,394 (GRCm39)	critical splice donor site	probably null
R4120:Nav3	UTSW	10	109,739,605 (GRCm39)	critical splice donor site	probably null
R4244:Nav3	UTSW	10	109,605,157 (GRCm39)	missense	probably damaging	1.00
R4361:Nav3	UTSW	10	109,688,847 (GRCm39)	missense	probably damaging	1.00
R4512:Nav3	UTSW	10	109,529,943 (GRCm39)	missense	possibly damaging	0.89
R4514:Nav3	UTSW	10	109,529,943 (GRCm39)	missense	possibly damaging	0.89
R4700:Nav3	UTSW	10	109,600,796 (GRCm39)	missense	probably benign	0.10
R4815:Nav3	UTSW	10	109,659,413 (GRCm39)	missense	probably benign
R4981:Nav3	UTSW	10	109,716,553 (GRCm39)	missense	probably benign
R5042:Nav3	UTSW	10	109,605,129 (GRCm39)	missense	probably benign	0.27
R5251:Nav3	UTSW	10	109,689,114 (GRCm39)	missense	probably damaging	0.99
R5252:Nav3	UTSW	10	109,550,152 (GRCm39)	small deletion	probably benign
R5273:Nav3	UTSW	10	109,528,899 (GRCm39)	critical splice donor site	probably null
R5288:Nav3	UTSW	10	109,688,966 (GRCm39)	missense	probably benign	0.10
R5407:Nav3	UTSW	10	109,702,796 (GRCm39)	missense	probably benign	0.28
R5533:Nav3	UTSW	10	109,719,539 (GRCm39)	missense	possibly damaging	0.61
R5561:Nav3	UTSW	10	109,552,413 (GRCm39)	missense	probably damaging	1.00
R5577:Nav3	UTSW	10	109,605,264 (GRCm39)	missense	probably damaging	1.00
R5656:Nav3	UTSW	10	109,600,494 (GRCm39)	missense	probably damaging	0.96
R5872:Nav3	UTSW	10	109,600,648 (GRCm39)	missense	probably damaging	1.00
R6023:Nav3	UTSW	10	109,659,376 (GRCm39)	missense	possibly damaging	0.95
R6061:Nav3	UTSW	10	109,702,845 (GRCm39)	nonsense	probably null
R6189:Nav3	UTSW	10	109,555,880 (GRCm39)	missense	probably damaging	0.98
R6214:Nav3	UTSW	10	109,688,426 (GRCm39)	missense	probably damaging	1.00
R6215:Nav3	UTSW	10	109,688,426 (GRCm39)	missense	probably damaging	1.00
R6264:Nav3	UTSW	10	109,524,694 (GRCm39)	missense	probably damaging	0.97
R6500:Nav3	UTSW	10	109,600,617 (GRCm39)	missense	probably damaging	1.00
R6524:Nav3	UTSW	10	109,555,891 (GRCm39)	missense	probably damaging	0.99
R6868:Nav3	UTSW	10	109,529,027 (GRCm39)	missense	possibly damaging	0.49
R7079:Nav3	UTSW	10	109,603,153 (GRCm39)	missense	probably benign	0.16
R7099:Nav3	UTSW	10	109,539,195 (GRCm39)	missense	probably benign	0.11
R7139:Nav3	UTSW	10	109,689,338 (GRCm39)	missense	probably benign	0.44
R7238:Nav3	UTSW	10	109,689,185 (GRCm39)	missense	possibly damaging	0.75
R7338:Nav3	UTSW	10	109,605,073 (GRCm39)	missense	probably benign	0.04
R7343:Nav3	UTSW	10	109,739,619 (GRCm39)	missense	probably damaging	0.98
R7383:Nav3	UTSW	10	109,552,532 (GRCm39)	missense	probably damaging	0.98
R7391:Nav3	UTSW	10	109,539,317 (GRCm39)	missense	probably benign	0.07
R7399:Nav3	UTSW	10	109,688,795 (GRCm39)	missense	possibly damaging	0.74
R7457:Nav3	UTSW	10	109,532,189 (GRCm39)	nonsense	probably null
R7462:Nav3	UTSW	10	109,659,439 (GRCm39)	missense	probably damaging	1.00
R7542:Nav3	UTSW	10	109,659,394 (GRCm39)	missense	possibly damaging	0.89
R7659:Nav3	UTSW	10	109,602,851 (GRCm39)	missense	probably benign	0.09
R7749:Nav3	UTSW	10	109,539,213 (GRCm39)	missense	probably damaging	0.99
R7794:Nav3	UTSW	10	109,524,717 (GRCm39)	missense	probably benign	0.08
R7876:Nav3	UTSW	10	109,689,359 (GRCm39)	missense	probably benign	0.26
R8048:Nav3	UTSW	10	109,600,779 (GRCm39)	missense	probably benign	0.13
R8104:Nav3	UTSW	10	109,594,828 (GRCm39)	missense	probably damaging	0.99
R8125:Nav3	UTSW	10	109,688,520 (GRCm39)	missense	probably damaging	0.99
R8275:Nav3	UTSW	10	109,527,984 (GRCm39)	missense	noncoding transcript
R8325:Nav3	UTSW	10	109,541,464 (GRCm39)	missense	probably benign	0.24
R8336:Nav3	UTSW	10	109,603,430 (GRCm39)	missense	probably damaging	0.99
R8523:Nav3	UTSW	10	109,659,138 (GRCm39)	missense	probably damaging	1.00
R8529:Nav3	UTSW	10	109,689,192 (GRCm39)	missense	probably benign	0.09
R8745:Nav3	UTSW	10	109,659,311 (GRCm39)	missense	probably benign	0.08
R8752:Nav3	UTSW	10	109,596,165 (GRCm39)	intron	probably benign
R8794:Nav3	UTSW	10	109,605,032 (GRCm39)	nonsense	probably null
R8816:Nav3	UTSW	10	109,699,721 (GRCm39)	missense	possibly damaging	0.69
R9029:Nav3	UTSW	10	109,699,613 (GRCm39)	missense	possibly damaging	0.68
R9117:Nav3	UTSW	10	109,520,100 (GRCm39)	missense	probably benign	0.41
R9126:Nav3	UTSW	10	109,541,524 (GRCm39)	missense	probably benign
R9258:Nav3	UTSW	10	109,550,243 (GRCm39)	missense	probably damaging	0.99
R9347:Nav3	UTSW	10	109,738,955 (GRCm39)	missense	probably damaging	0.98
R9353:Nav3	UTSW	10	109,554,065 (GRCm39)	missense	probably damaging	0.99
R9366:Nav3	UTSW	10	109,659,364 (GRCm39)	missense	probably damaging	0.99
R9384:Nav3	UTSW	10	109,554,158 (GRCm39)	missense	probably damaging	0.98
R9428:Nav3	UTSW	10	109,605,176 (GRCm39)	missense	probably benign
R9454:Nav3	UTSW	10	109,835,864 (GRCm39)	missense	probably benign	0.01
R9516:Nav3	UTSW	10	109,520,015 (GRCm39)	missense	probably damaging	1.00
R9521:Nav3	UTSW	10	109,835,845 (GRCm39)	missense	possibly damaging	0.95
R9622:Nav3	UTSW	10	109,603,103 (GRCm39)	missense	probably benign
R9689:Nav3	UTSW	10	109,605,034 (GRCm39)	missense	probably damaging	1.00
R9796:Nav3	UTSW	10	109,527,969 (GRCm39)	missense	probably damaging	0.99
X0012:Nav3	UTSW	10	109,527,958 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AAGACCTTGCTCCCACTGTATGCCAC -3'
(R):5'- GAAGGGATCAGCTTTGTGCTTTCGC -3'

Sequencing Primer
(F):5'- TGGTCACAAAGGTTGCCATC -3'
(R):5'- CAGGAGTTTAGGGCTACACGAT -3'

Posted On

2014-03-28