Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01321:Dync1h1'

74065

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dync1h1

Ensembl Gene

ENSMUSG00000018707

Gene Name

dynein cytoplasmic 1 heavy chain 1

Synonyms

MAP1C, Loa, Dnec1, Dnchc1, dynein heavy chain, retrograde transport, 9930018I23Rik, Swl

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01321

Quality Score

Status

Chromosome

Chromosomal Location

110567886-110633379 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 110592041 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000018851 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000018851]

AlphaFold

no structure available at present

PDB Structure

Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase [X-RAY DIFFRACTION]
High affinity dynein microtubule binding domain - tubulin complex [ELECTRON MICROSCOPY]
Low affinity dynein microtubule binding domain - tubulin complex [ELECTRON MICROSCOPY]
Structure of the entire stalk region of the dynein motor domain [X-RAY DIFFRACTION]

Predicted Effect

probably benign
Transcript: ENSMUST00000018851

SMART Domains

Protein: ENSMUSP00000018851
Gene: ENSMUSG00000018707

Domain	Start	End	E-Value	Type
low complexity region	46	61	N/A	INTRINSIC
low complexity region	83	95	N/A	INTRINSIC
Pfam:DHC_N1	237	830	1.9e-145	PFAM
coiled coil region	1171	1198	N/A	INTRINSIC
Pfam:DHC_N2	1317	1721	3.3e-116	PFAM
AAA	1899	2043	5.39e-2	SMART
low complexity region	2102	2116	N/A	INTRINSIC
AAA	2214	2365	2.13e0	SMART
low complexity region	2394	2405	N/A	INTRINSIC
AAA	2585	2735	8.6e-7	SMART
Blast:AAA	2777	2811	2e-13	BLAST
AAA	2927	3093	4.79e-5	SMART
Pfam:MT	3197	3534	1.1e-44	PFAM
Pfam:AAA_9	3554	3778	8.5e-75	PFAM
Pfam:Dynein_heavy	3919	4642	4.3e-163	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]
PHENOTYPE: Mice homozygous for either the Cra1 or Loa ENU mutation exhibit neonatal lethality with reduced anterior horn cell number, abnormal motor neuron innervation, neuronal inclusions, and abnormal axonal transport. Heterozygotes display motor neuron degeneration and muscle spasms. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acnat2	A	G	4: 49,380,269 (GRCm39)	S370P	probably damaging	Het
Adamts5	T	C	16: 85,696,363 (GRCm39)	R265G	probably benign	Het
Cd2ap	T	C	17: 43,156,280 (GRCm39)	S86G	possibly damaging	Het
Cers3	A	C	7: 66,435,751 (GRCm39)		probably benign	Het
Dnaaf2	G	T	12: 69,243,376 (GRCm39)	P562T	probably damaging	Het
Dnajc21	A	C	15: 10,447,188 (GRCm39)	V520G	probably benign	Het
Extl3	T	C	14: 65,304,211 (GRCm39)	N733D	probably benign	Het
Gm5499	T	A	17: 87,385,928 (GRCm39)		noncoding transcript	Het
Gstm6	T	C	3: 107,848,379 (GRCm39)	Q180R	probably benign	Het
Hdlbp	G	A	1: 93,351,524 (GRCm39)	R460W	probably damaging	Het
Ift81	T	C	5: 122,749,031 (GRCm39)	D40G	probably damaging	Het
Igsf3	T	A	3: 101,334,338 (GRCm39)		probably benign	Het
Kcnb2	A	G	1: 15,383,147 (GRCm39)	T158A	probably benign	Het
Lrrc59	C	T	11: 94,529,426 (GRCm39)	R167*	probably null	Het
Macf1	A	G	4: 123,334,567 (GRCm39)	C4397R	probably damaging	Het
Morc1	T	C	16: 48,402,825 (GRCm39)	S583P	probably benign	Het
Mucl3	A	T	17: 35,947,758 (GRCm39)	N490K	probably damaging	Het
Nipsnap2	T	A	5: 129,834,205 (GRCm39)	*282R	probably null	Het
Or2ag19	T	C	7: 106,443,956 (GRCm39)	L46P	probably damaging	Het
Or9m1b	A	T	2: 87,836,589 (GRCm39)	C178S	probably damaging	Het
Parp14	T	A	16: 35,676,929 (GRCm39)	Q1013L	probably benign	Het
Pdzd8	A	C	19: 59,289,961 (GRCm39)	S480A	probably benign	Het
Piezo1	A	T	8: 123,214,339 (GRCm39)	S1609R	probably damaging	Het
Pkp4	G	A	2: 59,180,971 (GRCm39)		probably null	Het
Plpp2	A	T	10: 79,363,327 (GRCm39)	V106D	probably damaging	Het
Rimbp2	T	C	5: 128,863,816 (GRCm39)	Y724C	probably benign	Het
Rpgrip1l	A	T	8: 91,987,501 (GRCm39)	L852*	probably null	Het
Samd9l	T	A	6: 3,376,259 (GRCm39)	D334V	probably benign	Het
Sipa1l2	G	A	8: 126,218,257 (GRCm39)	T360M	probably damaging	Het
Slc30a2	A	T	4: 134,070,611 (GRCm39)	D5V	probably damaging	Het
Spata31	T	C	13: 65,069,568 (GRCm39)	I572T	probably benign	Het
Tma16	G	A	8: 66,929,512 (GRCm39)	L161F	probably benign	Het
Trappc2b	A	T	11: 51,576,670 (GRCm39)	V76D	probably damaging	Het
Trim69	A	T	2: 122,003,765 (GRCm39)	E238V	possibly damaging	Het
Zfhx4	A	G	3: 5,307,388 (GRCm39)	T205A	probably benign	Het

Other mutations in Dync1h1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01291:Dync1h1	APN	12	110,615,538 (GRCm39)	missense	probably benign	0.31
IGL01299:Dync1h1	APN	12	110,580,541 (GRCm39)	missense	probably benign	0.04
IGL01324:Dync1h1	APN	12	110,593,299 (GRCm39)	missense	probably damaging	0.99
IGL01327:Dync1h1	APN	12	110,583,126 (GRCm39)	splice site	probably benign
IGL01371:Dync1h1	APN	12	110,605,285 (GRCm39)	missense	probably benign	0.05
IGL01598:Dync1h1	APN	12	110,624,562 (GRCm39)	missense	probably damaging	0.99
IGL01782:Dync1h1	APN	12	110,581,374 (GRCm39)	missense	probably damaging	1.00
IGL01791:Dync1h1	APN	12	110,625,364 (GRCm39)	missense	probably damaging	0.99
IGL01797:Dync1h1	APN	12	110,618,630 (GRCm39)	critical splice donor site	probably null
IGL02040:Dync1h1	APN	12	110,603,558 (GRCm39)	missense	probably benign	0.21
IGL02096:Dync1h1	APN	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
IGL02164:Dync1h1	APN	12	110,628,993 (GRCm39)	missense	probably damaging	1.00
IGL02216:Dync1h1	APN	12	110,629,436 (GRCm39)	missense	probably damaging	0.98
IGL02298:Dync1h1	APN	12	110,607,322 (GRCm39)	missense	probably damaging	1.00
IGL02422:Dync1h1	APN	12	110,606,644 (GRCm39)	missense	possibly damaging	0.68
IGL02610:Dync1h1	APN	12	110,625,666 (GRCm39)	nonsense	probably null
IGL02643:Dync1h1	APN	12	110,625,706 (GRCm39)	unclassified	probably benign
IGL03076:Dync1h1	APN	12	110,624,327 (GRCm39)	missense	probably damaging	1.00
IGL03292:Dync1h1	APN	12	110,632,989 (GRCm39)	splice site	probably null
IGL03293:Dync1h1	APN	12	110,595,168 (GRCm39)	missense	probably benign	0.12
IGL03299:Dync1h1	APN	12	110,585,644 (GRCm39)	missense	possibly damaging	0.49
chinashop	UTSW	12	110,624,568 (GRCm39)	missense	probably damaging	1.00
Gesund	UTSW	12	110,582,838 (GRCm39)	missense	probably benign	0.35
gymnast	UTSW	12	110,584,802 (GRCm39)	missense	probably damaging	1.00
Lightfoot	UTSW	12	110,584,354 (GRCm39)	missense	probably damaging	1.00
Lissom	UTSW	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
Strong	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
waters	UTSW	12	110,596,113 (GRCm39)	missense	probably damaging	1.00
ANU05:Dync1h1	UTSW	12	110,615,538 (GRCm39)	missense	probably benign	0.31
H8562:Dync1h1	UTSW	12	110,583,241 (GRCm39)	missense	probably benign	0.01
R0082:Dync1h1	UTSW	12	110,602,880 (GRCm39)	missense	probably benign
R0110:Dync1h1	UTSW	12	110,606,378 (GRCm39)	missense	probably benign	0.42
R0130:Dync1h1	UTSW	12	110,585,108 (GRCm39)	missense	probably benign	0.16
R0233:Dync1h1	UTSW	12	110,607,414 (GRCm39)	missense	probably benign	0.45
R0233:Dync1h1	UTSW	12	110,607,414 (GRCm39)	missense	probably benign	0.45
R0242:Dync1h1	UTSW	12	110,616,285 (GRCm39)	missense	possibly damaging	0.67
R0242:Dync1h1	UTSW	12	110,616,285 (GRCm39)	missense	possibly damaging	0.67
R0408:Dync1h1	UTSW	12	110,598,126 (GRCm39)	missense	probably benign
R0450:Dync1h1	UTSW	12	110,606,378 (GRCm39)	missense	probably benign	0.42
R0611:Dync1h1	UTSW	12	110,599,222 (GRCm39)	missense	probably damaging	0.97
R0612:Dync1h1	UTSW	12	110,582,930 (GRCm39)	missense	probably damaging	1.00
R0624:Dync1h1	UTSW	12	110,618,181 (GRCm39)	unclassified	probably benign
R0685:Dync1h1	UTSW	12	110,623,626 (GRCm39)	missense	probably damaging	1.00
R0747:Dync1h1	UTSW	12	110,595,718 (GRCm39)	missense	probably damaging	0.99
R0747:Dync1h1	UTSW	12	110,578,845 (GRCm39)	missense	probably benign
R0843:Dync1h1	UTSW	12	110,631,647 (GRCm39)	missense	possibly damaging	0.81
R0970:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1161:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1211:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1214:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1215:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1227:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1230:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1232:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1237:Dync1h1	UTSW	12	110,632,393 (GRCm39)	missense	probably benign	0.00
R1274:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1275:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1289:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1290:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1331:Dync1h1	UTSW	12	110,615,698 (GRCm39)	missense	probably damaging	0.98
R1340:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1383:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1394:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1396:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1397:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1413:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1432:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1500:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1661:Dync1h1	UTSW	12	110,622,791 (GRCm39)	missense	probably damaging	1.00
R1678:Dync1h1	UTSW	12	110,632,096 (GRCm39)	critical splice acceptor site	probably null
R1698:Dync1h1	UTSW	12	110,593,426 (GRCm39)	missense	possibly damaging	0.88
R1767:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1776:Dync1h1	UTSW	12	110,599,362 (GRCm39)	splice site	probably benign
R1812:Dync1h1	UTSW	12	110,629,334 (GRCm39)	missense	possibly damaging	0.46
R1831:Dync1h1	UTSW	12	110,580,493 (GRCm39)	missense	probably damaging	1.00
R1832:Dync1h1	UTSW	12	110,580,493 (GRCm39)	missense	probably damaging	1.00
R1856:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1857:Dync1h1	UTSW	12	110,629,059 (GRCm39)	missense	probably damaging	0.96
R1879:Dync1h1	UTSW	12	110,591,070 (GRCm39)	missense	probably benign	0.04
R1892:Dync1h1	UTSW	12	110,612,738 (GRCm39)	missense	probably damaging	1.00
R1909:Dync1h1	UTSW	12	110,629,063 (GRCm39)	missense	probably damaging	1.00
R1962:Dync1h1	UTSW	12	110,602,943 (GRCm39)	missense	probably benign	0.04
R1974:Dync1h1	UTSW	12	110,592,166 (GRCm39)	missense	possibly damaging	0.80
R1999:Dync1h1	UTSW	12	110,632,857 (GRCm39)	critical splice donor site	probably null
R2073:Dync1h1	UTSW	12	110,581,026 (GRCm39)	missense	probably damaging	1.00
R2091:Dync1h1	UTSW	12	110,616,022 (GRCm39)	missense	probably benign	0.07
R2113:Dync1h1	UTSW	12	110,596,420 (GRCm39)	missense	probably damaging	1.00
R2128:Dync1h1	UTSW	12	110,607,316 (GRCm39)	missense	probably damaging	1.00
R2134:Dync1h1	UTSW	12	110,623,065 (GRCm39)	missense	possibly damaging	0.68
R2496:Dync1h1	UTSW	12	110,607,654 (GRCm39)	missense	possibly damaging	0.65
R2680:Dync1h1	UTSW	12	110,609,681 (GRCm39)	missense	probably damaging	1.00
R2890:Dync1h1	UTSW	12	110,583,325 (GRCm39)	missense	probably damaging	1.00
R2964:Dync1h1	UTSW	12	110,607,460 (GRCm39)	critical splice donor site	probably null
R3705:Dync1h1	UTSW	12	110,607,020 (GRCm39)	missense	possibly damaging	0.80
R3708:Dync1h1	UTSW	12	110,609,563 (GRCm39)	missense	probably damaging	0.96
R3735:Dync1h1	UTSW	12	110,598,109 (GRCm39)	missense	probably benign
R3736:Dync1h1	UTSW	12	110,598,109 (GRCm39)	missense	probably benign
R3882:Dync1h1	UTSW	12	110,595,492 (GRCm39)	missense	probably benign	0.41
R3971:Dync1h1	UTSW	12	110,632,399 (GRCm39)	missense	probably benign	0.00
R4017:Dync1h1	UTSW	12	110,609,624 (GRCm39)	missense	probably damaging	1.00
R4032:Dync1h1	UTSW	12	110,584,483 (GRCm39)	nonsense	probably null
R4355:Dync1h1	UTSW	12	110,599,333 (GRCm39)	missense	possibly damaging	0.55
R4514:Dync1h1	UTSW	12	110,623,573 (GRCm39)	missense	possibly damaging	0.76
R4586:Dync1h1	UTSW	12	110,615,917 (GRCm39)	missense	probably benign	0.30
R4619:Dync1h1	UTSW	12	110,605,278 (GRCm39)	missense	probably benign	0.09
R4659:Dync1h1	UTSW	12	110,595,201 (GRCm39)	missense	possibly damaging	0.50
R4676:Dync1h1	UTSW	12	110,628,975 (GRCm39)	missense	probably damaging	0.99
R4688:Dync1h1	UTSW	12	110,621,962 (GRCm39)	missense	probably damaging	0.99
R4732:Dync1h1	UTSW	12	110,615,941 (GRCm39)	nonsense	probably null
R4733:Dync1h1	UTSW	12	110,615,941 (GRCm39)	nonsense	probably null
R4780:Dync1h1	UTSW	12	110,627,630 (GRCm39)	missense	probably damaging	1.00
R4846:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4861:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4861:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4865:Dync1h1	UTSW	12	110,606,235 (GRCm39)	missense	possibly damaging	0.84
R4872:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4873:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4874:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4875:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4927:Dync1h1	UTSW	12	110,629,289 (GRCm39)	missense	possibly damaging	0.82
R4949:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4954:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4956:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4957:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4958:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4984:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4985:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R4988:Dync1h1	UTSW	12	110,624,560 (GRCm39)	missense	probably damaging	1.00
R5029:Dync1h1	UTSW	12	110,584,444 (GRCm39)	missense	possibly damaging	0.46
R5032:Dync1h1	UTSW	12	110,593,326 (GRCm39)	nonsense	probably null
R5036:Dync1h1	UTSW	12	110,596,969 (GRCm39)	missense	probably damaging	1.00
R5037:Dync1h1	UTSW	12	110,607,341 (GRCm39)	missense	probably benign	0.09
R5105:Dync1h1	UTSW	12	110,584,366 (GRCm39)	missense	probably damaging	0.99
R5122:Dync1h1	UTSW	12	110,596,114 (GRCm39)	missense	probably damaging	1.00
R5156:Dync1h1	UTSW	12	110,595,264 (GRCm39)	missense	probably benign	0.00
R5290:Dync1h1	UTSW	12	110,581,502 (GRCm39)	missense	probably benign	0.03
R5453:Dync1h1	UTSW	12	110,599,099 (GRCm39)	missense	probably benign	0.12
R5540:Dync1h1	UTSW	12	110,627,384 (GRCm39)	missense	probably benign	0.00
R5613:Dync1h1	UTSW	12	110,599,254 (GRCm39)	missense	possibly damaging	0.68
R5626:Dync1h1	UTSW	12	110,607,575 (GRCm39)	missense	probably benign	0.01
R5652:Dync1h1	UTSW	12	110,632,422 (GRCm39)	missense	possibly damaging	0.70
R5655:Dync1h1	UTSW	12	110,595,496 (GRCm39)	missense	probably benign	0.03
R5686:Dync1h1	UTSW	12	110,582,838 (GRCm39)	missense	probably benign	0.35
R5772:Dync1h1	UTSW	12	110,612,707 (GRCm39)	nonsense	probably null
R5806:Dync1h1	UTSW	12	110,618,087 (GRCm39)	missense	probably damaging	1.00
R5891:Dync1h1	UTSW	12	110,580,654 (GRCm39)	critical splice donor site	probably null
R5921:Dync1h1	UTSW	12	110,584,802 (GRCm39)	missense	probably damaging	1.00
R5965:Dync1h1	UTSW	12	110,599,212 (GRCm39)	missense	probably benign
R6113:Dync1h1	UTSW	12	110,586,848 (GRCm39)	missense	probably benign
R6119:Dync1h1	UTSW	12	110,594,440 (GRCm39)	missense	possibly damaging	0.82
R6154:Dync1h1	UTSW	12	110,584,427 (GRCm39)	missense	probably damaging	1.00
R6339:Dync1h1	UTSW	12	110,612,639 (GRCm39)	missense	probably damaging	0.97
R6522:Dync1h1	UTSW	12	110,583,171 (GRCm39)	missense	probably damaging	0.99
R6531:Dync1h1	UTSW	12	110,584,354 (GRCm39)	missense	probably damaging	1.00
R6554:Dync1h1	UTSW	12	110,616,282 (GRCm39)	missense	probably benign	0.06
R6672:Dync1h1	UTSW	12	110,624,568 (GRCm39)	missense	probably damaging	1.00
R6746:Dync1h1	UTSW	12	110,618,087 (GRCm39)	missense	probably damaging	1.00
R6785:Dync1h1	UTSW	12	110,596,113 (GRCm39)	missense	probably damaging	1.00
R6857:Dync1h1	UTSW	12	110,624,981 (GRCm39)	missense	possibly damaging	0.94
R6863:Dync1h1	UTSW	12	110,618,614 (GRCm39)	missense	probably benign	0.07
R6881:Dync1h1	UTSW	12	110,590,995 (GRCm39)	missense	probably damaging	1.00
R6892:Dync1h1	UTSW	12	110,605,335 (GRCm39)	missense	probably benign	0.00
R7015:Dync1h1	UTSW	12	110,632,521 (GRCm39)	nonsense	probably null
R7096:Dync1h1	UTSW	12	110,623,512 (GRCm39)	missense	probably damaging	0.99
R7173:Dync1h1	UTSW	12	110,568,173 (GRCm39)	missense	probably benign
R7224:Dync1h1	UTSW	12	110,584,196 (GRCm39)	missense	possibly damaging	0.93
R7295:Dync1h1	UTSW	12	110,631,183 (GRCm39)	critical splice donor site	probably null
R7308:Dync1h1	UTSW	12	110,631,596 (GRCm39)	missense	possibly damaging	0.91
R7346:Dync1h1	UTSW	12	110,602,076 (GRCm39)	missense	probably damaging	1.00
R7359:Dync1h1	UTSW	12	110,591,036 (GRCm39)	missense	probably benign	0.00
R7405:Dync1h1	UTSW	12	110,600,654 (GRCm39)	missense	probably damaging	1.00
R7439:Dync1h1	UTSW	12	110,602,887 (GRCm39)	missense	probably damaging	1.00
R7441:Dync1h1	UTSW	12	110,602,887 (GRCm39)	missense	probably damaging	1.00
R7472:Dync1h1	UTSW	12	110,632,109 (GRCm39)	missense	probably damaging	0.99
R7532:Dync1h1	UTSW	12	110,618,011 (GRCm39)	missense	probably benign	0.00
R7543:Dync1h1	UTSW	12	110,580,541 (GRCm39)	missense	probably benign	0.04
R7555:Dync1h1	UTSW	12	110,597,059 (GRCm39)	missense	probably benign	0.03
R7632:Dync1h1	UTSW	12	110,627,327 (GRCm39)	missense	probably benign	0.10
R7701:Dync1h1	UTSW	12	110,585,080 (GRCm39)	missense	probably damaging	1.00
R7704:Dync1h1	UTSW	12	110,632,200 (GRCm39)	missense	probably damaging	1.00
R7808:Dync1h1	UTSW	12	110,621,893 (GRCm39)	missense	possibly damaging	0.53
R7891:Dync1h1	UTSW	12	110,609,590 (GRCm39)	missense	probably benign	0.02
R7895:Dync1h1	UTSW	12	110,582,891 (GRCm39)	missense	probably damaging	1.00
R7913:Dync1h1	UTSW	12	110,595,168 (GRCm39)	missense	probably benign	0.12
R8164:Dync1h1	UTSW	12	110,582,794 (GRCm39)	missense	possibly damaging	0.91
R8257:Dync1h1	UTSW	12	110,602,908 (GRCm39)	missense	probably damaging	1.00
R8346:Dync1h1	UTSW	12	110,632,226 (GRCm39)	missense	probably benign	0.21
R8432:Dync1h1	UTSW	12	110,584,576 (GRCm39)	missense	probably benign	0.00
R8510:Dync1h1	UTSW	12	110,583,177 (GRCm39)	missense	possibly damaging	0.94
R8731:Dync1h1	UTSW	12	110,607,018 (GRCm39)	missense	possibly damaging	0.93
R8739:Dync1h1	UTSW	12	110,581,014 (GRCm39)	missense	probably damaging	1.00
R8756:Dync1h1	UTSW	12	110,583,261 (GRCm39)	missense	probably benign	0.06
R8855:Dync1h1	UTSW	12	110,602,333 (GRCm39)	missense	probably damaging	1.00
R8866:Dync1h1	UTSW	12	110,602,333 (GRCm39)	missense	probably damaging	1.00
R8885:Dync1h1	UTSW	12	110,583,172 (GRCm39)	missense	probably damaging	1.00
R8893:Dync1h1	UTSW	12	110,608,477 (GRCm39)	missense	probably damaging	1.00
R8913:Dync1h1	UTSW	12	110,624,602 (GRCm39)	missense	probably benign	0.14
R8937:Dync1h1	UTSW	12	110,584,471 (GRCm39)	missense	probably damaging	1.00
R8958:Dync1h1	UTSW	12	110,586,805 (GRCm39)	missense	probably benign	0.00
R9000:Dync1h1	UTSW	12	110,606,397 (GRCm39)	missense	probably benign
R9036:Dync1h1	UTSW	12	110,606,186 (GRCm39)	missense	probably benign
R9090:Dync1h1	UTSW	12	110,583,310 (GRCm39)	missense	probably benign	0.06
R9108:Dync1h1	UTSW	12	110,622,706 (GRCm39)	intron	probably benign
R9161:Dync1h1	UTSW	12	110,625,023 (GRCm39)	missense	probably benign	0.01
R9185:Dync1h1	UTSW	12	110,601,937 (GRCm39)	missense	probably benign	0.33
R9271:Dync1h1	UTSW	12	110,583,310 (GRCm39)	missense	probably benign	0.06
R9436:Dync1h1	UTSW	12	110,582,975 (GRCm39)	missense	probably damaging	1.00
R9478:Dync1h1	UTSW	12	110,625,137 (GRCm39)	missense	probably benign	0.02
R9547:Dync1h1	UTSW	12	110,624,805 (GRCm39)	missense	probably damaging	1.00
R9561:Dync1h1	UTSW	12	110,615,533 (GRCm39)	missense	probably damaging	0.99
R9586:Dync1h1	UTSW	12	110,582,975 (GRCm39)	missense	probably damaging	1.00
R9609:Dync1h1	UTSW	12	110,607,362 (GRCm39)	missense	probably benign	0.01
Z1088:Dync1h1	UTSW	12	110,596,351 (GRCm39)	frame shift	probably null
Z1177:Dync1h1	UTSW	12	110,624,951 (GRCm39)	nonsense	probably null
Z1177:Dync1h1	UTSW	12	110,607,611 (GRCm39)	frame shift	probably null
Z1177:Dync1h1	UTSW	12	110,603,988 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-10-07