Incidental Mutation 'R6860:Fan1'
| ID |
535438 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fan1
|
| Ensembl Gene |
ENSMUSG00000033458 |
| Gene Name |
FANCD2/FANCI-associated nuclease 1 |
| Synonyms |
Mtmr15, 6030441H18Rik |
| MMRRC Submission |
045025-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R6860 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
63996506-64023843 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 64022234 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Tyrosine
at position 340
(N340Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032735]
[ENSMUST00000163289]
|
| AlphaFold |
Q69ZT1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032735
|
| SMART Domains |
Protein: ENSMUSP00000032735
Gene: ENSMUSG00000030521
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Mpp10
|
20 |
654 |
6.9e-217 |
PFAM |
|
low complexity region
|
666 |
671 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163289
AA Change: N340Y
PolyPhen 2
Score 0.974 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000130012
Gene: ENSMUSG00000033458
AA Change: N340Y
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
600 |
737 |
5e-5 |
SMART |
|
Blast:VRR_NUC
|
834 |
867 |
2e-12 |
BLAST |
|
VRR_NUC
|
896 |
1011 |
1.99e-37 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206047
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206329
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206778
|
| Meta Mutation Damage Score |
0.1011 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.3%
|
| Validation Efficiency |
100% (86/86) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016]
PHENOTYPE: Mice homozygous for mutations in this gene display renal tubular karyomegaly with polyploidy and defects in interstrand cross-link DNA repair. Some homozygous mice also display hepatocyte karyomegaly and liver dysfunction. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933427D14Rik |
T |
C |
11: 72,080,412 (GRCm39) |
E418G |
probably damaging |
Het |
| 9930012K11Rik |
C |
A |
14: 70,395,071 (GRCm39) |
V28L |
possibly damaging |
Het |
| Abtb2 |
C |
T |
2: 103,539,770 (GRCm39) |
R712* |
probably null |
Het |
| Acvr1c |
C |
T |
2: 58,177,717 (GRCm39) |
G171S |
probably damaging |
Het |
| Ahctf1 |
G |
T |
1: 179,580,853 (GRCm39) |
A1783E |
probably benign |
Het |
| Anapc4 |
A |
T |
5: 53,006,170 (GRCm39) |
Q149L |
probably damaging |
Het |
| Ankrd27 |
T |
C |
7: 35,327,952 (GRCm39) |
V824A |
possibly damaging |
Het |
| Ankrd31 |
G |
C |
13: 96,968,094 (GRCm39) |
C577S |
probably benign |
Het |
| Apol7c |
T |
C |
15: 77,410,274 (GRCm39) |
N224S |
probably benign |
Het |
| Arl14 |
A |
T |
3: 69,130,029 (GRCm39) |
T59S |
probably benign |
Het |
| Astn1 |
T |
A |
1: 158,440,042 (GRCm39) |
I870K |
probably damaging |
Het |
| B4galt1 |
A |
T |
4: 40,807,796 (GRCm39) |
V335E |
probably benign |
Het |
| C2cd3 |
C |
T |
7: 100,039,448 (GRCm39) |
P216S |
probably benign |
Het |
| Cchcr1 |
C |
A |
17: 35,840,015 (GRCm39) |
N711K |
possibly damaging |
Het |
| Chd2 |
A |
G |
7: 73,147,558 (GRCm39) |
F467L |
possibly damaging |
Het |
| Cntn6 |
A |
T |
6: 104,838,907 (GRCm39) |
E987V |
possibly damaging |
Het |
| Col11a2 |
T |
A |
17: 34,272,572 (GRCm39) |
L286H |
probably damaging |
Het |
| Cwc22 |
C |
T |
2: 77,759,792 (GRCm39) |
R85Q |
possibly damaging |
Het |
| Cyp7a1 |
A |
C |
4: 6,272,587 (GRCm39) |
F209V |
probably damaging |
Het |
| Dmtn |
T |
C |
14: 70,852,322 (GRCm39) |
T189A |
possibly damaging |
Het |
| Dnhd1 |
C |
G |
7: 105,327,473 (GRCm39) |
N777K |
probably benign |
Het |
| Dusp16 |
A |
T |
6: 134,702,842 (GRCm39) |
C216* |
probably null |
Het |
| Fbn1 |
T |
C |
2: 125,170,078 (GRCm39) |
N1993S |
probably damaging |
Het |
| Fbxw22 |
A |
G |
9: 109,213,030 (GRCm39) |
S306P |
probably benign |
Het |
| Ferd3l |
T |
C |
12: 33,978,651 (GRCm39) |
S55P |
probably benign |
Het |
| Fpr-rs3 |
A |
G |
17: 20,844,560 (GRCm39) |
S194P |
possibly damaging |
Het |
| Gm19965 |
G |
A |
1: 116,748,609 (GRCm39) |
D97N |
probably benign |
Het |
| Gtpbp2 |
A |
G |
17: 46,478,914 (GRCm39) |
|
probably benign |
Het |
| H3c7 |
G |
T |
13: 23,728,760 (GRCm39) |
V36L |
probably benign |
Het |
| Hcn3 |
A |
C |
3: 89,067,152 (GRCm39) |
I72S |
possibly damaging |
Het |
| Hk3 |
T |
A |
13: 55,162,278 (GRCm39) |
N109Y |
probably damaging |
Het |
| Iqub |
T |
C |
6: 24,505,737 (GRCm39) |
E57G |
possibly damaging |
Het |
| Kcnk3 |
T |
A |
5: 30,779,397 (GRCm39) |
M149K |
possibly damaging |
Het |
| Kcp |
C |
T |
6: 29,505,719 (GRCm39) |
G51D |
probably benign |
Het |
| Kif26a |
C |
A |
12: 112,113,263 (GRCm39) |
A53D |
probably damaging |
Het |
| Lifr |
T |
A |
15: 7,202,418 (GRCm39) |
I353K |
probably benign |
Het |
| Llph |
A |
T |
10: 120,067,189 (GRCm39) |
N102I |
probably damaging |
Het |
| Lmo3 |
C |
A |
6: 138,393,566 (GRCm39) |
R18L |
possibly damaging |
Het |
| Lrrc46 |
T |
C |
11: 96,926,371 (GRCm39) |
E175G |
probably benign |
Het |
| Ltk |
A |
T |
2: 119,585,075 (GRCm39) |
C128* |
probably null |
Het |
| Map1b |
T |
C |
13: 99,571,275 (GRCm39) |
E482G |
probably damaging |
Het |
| Mapk8ip2 |
T |
C |
15: 89,344,655 (GRCm39) |
V740A |
probably damaging |
Het |
| Miga2 |
T |
C |
2: 30,261,175 (GRCm39) |
W157R |
probably benign |
Het |
| Mlip |
A |
G |
9: 77,009,675 (GRCm39) |
*837Q |
probably null |
Het |
| Mroh2a |
G |
T |
1: 88,182,657 (GRCm39) |
R1195L |
possibly damaging |
Het |
| Myl1 |
T |
C |
1: 66,984,217 (GRCm39) |
|
probably benign |
Het |
| Or1l4 |
T |
C |
2: 37,092,189 (GRCm39) |
L312P |
possibly damaging |
Het |
| Or2a5 |
T |
C |
6: 42,873,750 (GRCm39) |
Y122H |
probably benign |
Het |
| Or51ab3 |
A |
G |
7: 103,201,075 (GRCm39) |
I28V |
probably benign |
Het |
| P3h3 |
A |
T |
6: 124,834,331 (GRCm39) |
V107D |
probably benign |
Het |
| Papolb |
A |
T |
5: 142,514,651 (GRCm39) |
S331T |
possibly damaging |
Het |
| Pars2 |
T |
G |
4: 106,511,700 (GRCm39) |
V494G |
probably benign |
Het |
| Pcdhb3 |
C |
A |
18: 37,434,763 (GRCm39) |
T243K |
probably benign |
Het |
| Pde9a |
T |
A |
17: 31,689,698 (GRCm39) |
M415K |
probably damaging |
Het |
| Ppp1r9b |
G |
A |
11: 94,882,974 (GRCm39) |
A201T |
probably benign |
Het |
| Prl |
A |
G |
13: 27,248,942 (GRCm39) |
N197S |
possibly damaging |
Het |
| Prl2c1 |
T |
A |
13: 28,035,724 (GRCm39) |
M32K |
probably benign |
Het |
| Prrt4 |
T |
C |
6: 29,170,737 (GRCm39) |
S572G |
possibly damaging |
Het |
| Psd |
T |
A |
19: 46,310,858 (GRCm39) |
D397V |
probably damaging |
Het |
| Psme2b |
A |
T |
11: 48,836,307 (GRCm39) |
Y213* |
probably null |
Het |
| Ptcd3 |
T |
A |
6: 71,874,094 (GRCm39) |
|
probably null |
Het |
| Ptprk |
T |
G |
10: 28,210,480 (GRCm39) |
F167L |
probably damaging |
Het |
| Rfx7 |
T |
C |
9: 72,524,226 (GRCm39) |
V472A |
probably damaging |
Het |
| Sanbr |
A |
G |
11: 23,575,100 (GRCm39) |
L58P |
probably damaging |
Het |
| Scnn1g |
T |
C |
7: 121,339,576 (GRCm39) |
L125S |
probably damaging |
Het |
| Sec16a |
T |
C |
2: 26,320,124 (GRCm39) |
Y1438C |
probably damaging |
Het |
| Serinc3 |
C |
T |
2: 163,476,366 (GRCm39) |
S155N |
probably benign |
Het |
| Slc3a2 |
A |
T |
19: 8,690,996 (GRCm39) |
V78E |
probably damaging |
Het |
| Slc44a4 |
T |
A |
17: 35,140,044 (GRCm39) |
L23Q |
probably damaging |
Het |
| Slco5a1 |
C |
T |
1: 12,951,420 (GRCm39) |
|
probably benign |
Het |
| Slit1 |
A |
G |
19: 41,605,154 (GRCm39) |
M899T |
probably benign |
Het |
| Sorl1 |
A |
G |
9: 41,933,688 (GRCm39) |
I1094T |
probably benign |
Het |
| Spag9 |
T |
A |
11: 93,972,196 (GRCm39) |
L258Q |
probably benign |
Het |
| Strip1 |
T |
C |
3: 107,526,252 (GRCm39) |
E488G |
possibly damaging |
Het |
| Stx18 |
G |
A |
5: 38,262,235 (GRCm39) |
D30N |
possibly damaging |
Het |
| Sync |
T |
C |
4: 129,181,583 (GRCm39) |
|
probably null |
Het |
| Syncrip |
A |
G |
9: 88,358,849 (GRCm39) |
V220A |
probably damaging |
Het |
| Tagln2 |
T |
C |
1: 172,333,476 (GRCm39) |
I110T |
probably benign |
Het |
| Taok1 |
T |
C |
11: 77,432,627 (GRCm39) |
T729A |
probably benign |
Het |
| Tgfbrap1 |
C |
T |
1: 43,106,759 (GRCm39) |
V75I |
possibly damaging |
Het |
| Tnfrsf21 |
A |
G |
17: 43,327,957 (GRCm39) |
T24A |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,932,131 (GRCm39) |
D2221E |
probably damaging |
Het |
| Triml1 |
A |
G |
8: 43,583,603 (GRCm39) |
S333P |
probably damaging |
Het |
| Trp53bp1 |
C |
A |
2: 121,029,594 (GRCm39) |
R1862L |
probably damaging |
Het |
| Tsc22d1 |
T |
G |
14: 76,655,732 (GRCm39) |
I737S |
possibly damaging |
Het |
| U2af2 |
A |
T |
7: 5,082,273 (GRCm39) |
K462N |
possibly damaging |
Het |
| Ubap2 |
A |
C |
4: 41,233,631 (GRCm39) |
N86K |
probably damaging |
Het |
| Uso1 |
A |
G |
5: 92,343,207 (GRCm39) |
K764E |
probably benign |
Het |
| Vmn1r192 |
T |
A |
13: 22,372,122 (GRCm39) |
M33L |
probably benign |
Het |
|
| Other mutations in Fan1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01648:Fan1
|
APN |
7 |
64,022,297 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01752:Fan1
|
APN |
7 |
64,022,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01971:Fan1
|
APN |
7 |
64,003,459 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02043:Fan1
|
APN |
7 |
64,021,367 (GRCm39) |
splice site |
probably null |
|
|
IGL02542:Fan1
|
APN |
7 |
64,014,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Fan1
|
APN |
7 |
64,022,741 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03111:Fan1
|
APN |
7 |
63,999,816 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
hitched
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stitched
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0270:Fan1
|
UTSW |
7 |
63,998,619 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0632:Fan1
|
UTSW |
7 |
64,012,947 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1714:Fan1
|
UTSW |
7 |
64,016,435 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1750:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1822:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2031:Fan1
|
UTSW |
7 |
64,004,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2107:Fan1
|
UTSW |
7 |
64,016,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2126:Fan1
|
UTSW |
7 |
63,996,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2873:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3849:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3850:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3949:Fan1
|
UTSW |
7 |
64,021,292 (GRCm39) |
nonsense |
probably null |
|
|
R4007:Fan1
|
UTSW |
7 |
64,016,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4490:Fan1
|
UTSW |
7 |
64,018,928 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4623:Fan1
|
UTSW |
7 |
64,023,301 (GRCm39) |
nonsense |
probably null |
|
|
R4918:Fan1
|
UTSW |
7 |
64,023,286 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5328:Fan1
|
UTSW |
7 |
64,004,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5691:Fan1
|
UTSW |
7 |
64,004,118 (GRCm39) |
splice site |
probably null |
|
|
R5902:Fan1
|
UTSW |
7 |
64,023,070 (GRCm39) |
splice site |
probably null |
|
|
R5905:Fan1
|
UTSW |
7 |
64,003,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6126:Fan1
|
UTSW |
7 |
64,014,318 (GRCm39) |
nonsense |
probably null |
|
|
R6195:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6434:Fan1
|
UTSW |
7 |
64,004,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6469:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6471:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6473:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6696:Fan1
|
UTSW |
7 |
63,999,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6708:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6713:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6714:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6749:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6841:Fan1
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6858:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6859:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6925:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6927:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6936:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6938:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6939:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7040:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7120:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7290:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7292:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7459:Fan1
|
UTSW |
7 |
63,998,714 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7464:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,003,386 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7608:Fan1
|
UTSW |
7 |
64,003,979 (GRCm39) |
splice site |
probably null |
|
|
R7624:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7629:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7682:Fan1
|
UTSW |
7 |
64,022,512 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7731:Fan1
|
UTSW |
7 |
64,022,444 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7863:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8054:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8055:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8057:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8058:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8101:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8241:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8262:Fan1
|
UTSW |
7 |
64,023,054 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8274:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8275:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8276:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8285:Fan1
|
UTSW |
7 |
64,016,348 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8318:Fan1
|
UTSW |
7 |
63,999,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8466:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8468:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Fan1
|
UTSW |
7 |
64,016,406 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8821:Fan1
|
UTSW |
7 |
64,004,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9030:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9181:Fan1
|
UTSW |
7 |
64,016,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Fan1
|
UTSW |
7 |
64,022,007 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9564:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9565:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9796:Fan1
|
UTSW |
7 |
64,022,278 (GRCm39) |
missense |
probably benign |
0.09 |
|
X0025:Fan1
|
UTSW |
7 |
64,022,583 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTCTCCTGCTCATCGAAGAG -3'
(R):5'- GTAACACGAAATCCTCTCCGG -3'
Sequencing Primer
(F):5'- TCATCGAAGAGCTTCATGTCC -3'
(R):5'- TCTCCGGGAGACACTCTTGTAAAG -3'
|
| Posted On |
2018-09-12 |
Incidental Mutation