Mutagenetix > Incidental Mutation

Incidental Mutation 'FR4976:Kmt2c'

511839

Institutional Source

Beutler Lab

Gene Symbol

Kmt2c

Ensembl Gene

ENSMUSG00000038056

Gene Name

lysine (K)-specific methyltransferase 2C

Synonyms

Mll3, HALR, E330008K23Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

FR4976 ()

Quality Score

214.458

Status

Not validated

Chromosome

Chromosomal Location

25476796-25703781 bp(-) (GRCm39)

Type of Mutation

small insertion (2 aa in frame mutation)

DNA Base Change (assembly)

TGCTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT to TGCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCT at 25520761 bp (GRCm39)

Zygosity

Homozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000134442 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045291] [ENSMUST00000173073]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000045291

SMART Domains

Protein: ENSMUSP00000043874
Gene: ENSMUSG00000038056

Domain	Start	End	E-Value	Type
low complexity region	9	32	N/A	INTRINSIC
AT_hook	34	46	9.68e-1	SMART
low complexity region	73	87	N/A	INTRINSIC
PHD	283	330	2.56e-2	SMART
C1	329	384	5.45e-1	SMART
PHD	342	388	4.19e-7	SMART
RING	343	387	1.45e-1	SMART
PHD	389	435	4.77e-11	SMART
RING	390	434	1.46e0	SMART
PHD	465	517	8.25e-6	SMART
low complexity region	776	789	N/A	INTRINSIC
AT_hook	898	910	1.41e2	SMART
PHD	953	1002	2.89e-10	SMART
RING	954	1001	4.74e0	SMART
C1	994	1045	8.38e-2	SMART
PHD	1003	1049	1.05e-12	SMART
PHD	1080	1131	2.08e-2	SMART
low complexity region	1189	1201	N/A	INTRINSIC
low complexity region	1337	1348	N/A	INTRINSIC
low complexity region	1394	1406	N/A	INTRINSIC
low complexity region	1431	1442	N/A	INTRINSIC
low complexity region	1520	1539	N/A	INTRINSIC
low complexity region	1557	1570	N/A	INTRINSIC
HMG	1639	1703	2.64e-3	SMART
low complexity region	1708	1724	N/A	INTRINSIC
coiled coil region	1745	1789	N/A	INTRINSIC
low complexity region	1847	1860	N/A	INTRINSIC
low complexity region	1864	1891	N/A	INTRINSIC
internal_repeat_3	1893	2084	1.27e-14	PROSPERO
internal_repeat_3	2123	2306	1.27e-14	PROSPERO
low complexity region	2336	2348	N/A	INTRINSIC
low complexity region	2375	2394	N/A	INTRINSIC
low complexity region	2427	2440	N/A	INTRINSIC
low complexity region	2516	2527	N/A	INTRINSIC
low complexity region	2696	2720	N/A	INTRINSIC
low complexity region	2723	2742	N/A	INTRINSIC
low complexity region	2930	2943	N/A	INTRINSIC
coiled coil region	3048	3075	N/A	INTRINSIC
low complexity region	3156	3165	N/A	INTRINSIC
low complexity region	3173	3195	N/A	INTRINSIC
coiled coil region	3226	3270	N/A	INTRINSIC
low complexity region	3277	3290	N/A	INTRINSIC
coiled coil region	3389	3427	N/A	INTRINSIC
low complexity region	3460	3486	N/A	INTRINSIC
low complexity region	3597	3611	N/A	INTRINSIC
low complexity region	3649	3667	N/A	INTRINSIC
low complexity region	3769	3783	N/A	INTRINSIC
low complexity region	3822	3827	N/A	INTRINSIC
low complexity region	3860	3869	N/A	INTRINSIC
low complexity region	3887	3904	N/A	INTRINSIC
low complexity region	3994	4009	N/A	INTRINSIC
low complexity region	4015	4038	N/A	INTRINSIC
low complexity region	4293	4309	N/A	INTRINSIC
low complexity region	4412	4419	N/A	INTRINSIC
PHD	4454	4500	2.94e-2	SMART
RING	4455	4499	8.1e0	SMART
FYRN	4554	4597	1.18e-21	SMART
FYRC	4603	4690	4.54e-32	SMART
SET	4764	4886	3.17e-34	SMART
PostSET	4888	4904	1.82e-6	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000173073

SMART Domains

Protein: ENSMUSP00000134442
Gene: ENSMUSG00000038056

Domain	Start	End	E-Value	Type
low complexity region	9	32	N/A	INTRINSIC
AT_hook	34	46	9.68e-1	SMART
low complexity region	73	87	N/A	INTRINSIC
PHD	283	330	2.56e-2	SMART
C1	329	384	5.45e-1	SMART
PHD	342	388	4.19e-7	SMART
RING	343	387	1.45e-1	SMART
PHD	389	435	4.77e-11	SMART
RING	390	434	1.46e0	SMART
PHD	465	517	8.25e-6	SMART
low complexity region	776	789	N/A	INTRINSIC
AT_hook	858	870	1.41e2	SMART
PHD	913	962	2.89e-10	SMART
RING	914	961	4.74e0	SMART
C1	954	1005	8.38e-2	SMART
PHD	963	1009	1.05e-12	SMART
PHD	1040	1091	2.08e-2	SMART
low complexity region	1149	1161	N/A	INTRINSIC
low complexity region	1297	1308	N/A	INTRINSIC
low complexity region	1354	1366	N/A	INTRINSIC
low complexity region	1445	1464	N/A	INTRINSIC
low complexity region	1482	1495	N/A	INTRINSIC
HMG	1564	1628	2.64e-3	SMART
low complexity region	1633	1649	N/A	INTRINSIC
coiled coil region	1670	1714	N/A	INTRINSIC

Coding Region Coverage

1x: 99.8%
3x: 99.6%
10x: 98.7%
20x: 96.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele display partial embryonic lethality, delayed eyelid opening, postnatal growth retardation, impaired fertility in both sexes, and decreased proliferation of cultured mouse embryonic fibroblasts. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 222 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700001K19Rik	TTC	TTCATC	12: 110,634,881 (GRCm39)		probably benign	Het
1700001K19Rik	TTC	TTCGTC	12: 110,634,884 (GRCm39)		probably benign	Het
Abt1	TTCTTGCT	TT	13: 23,607,881 (GRCm39)		probably benign	Het
AI837181	GGC	GGCCGC	19: 5,475,257 (GRCm39)		probably benign	Het
Akap12	AAA	AAACAA	10: 4,303,837 (GRCm39)		probably benign	Het
Alg1	GCTCACTCAC	GCTCAC	16: 5,062,425 (GRCm39)		probably null	Homo
Alg9	G	GCGA	9: 50,686,731 (GRCm39)		probably benign	Het
Amfr	GCC	GCCGGCGCGAGCTCC	8: 94,738,920 (GRCm39)		probably benign	Het
Anapc2	TGGCGGTGGCGGCGGCGGCGGCGGCGGCGG	TGGCGGCGGCGGCGGCGG	2: 25,162,544 (GRCm39)		probably benign	Het
Anxa7	C	T	14: 20,519,479 (GRCm39)	G113E	probably damaging	Homo
Apc	AATAAAGC	AATAAAGCCTATAAAGC	18: 34,415,053 (GRCm39)		probably benign	Het
Apc	CCAATAAAG	CCAATAAAGTCAATAAAG	18: 34,415,051 (GRCm39)		probably benign	Het
Apc	AAGC	AAGCCAATATAGC	18: 34,415,057 (GRCm39)		probably null	Het
Atad3a	C	A	4: 155,838,396 (GRCm39)	R207L	probably damaging	Homo
Blm	ACCT	ACCTCCCT	7: 80,113,515 (GRCm39)		probably benign	Homo
Blm	TCCTCCTCCTCCTCCTCCTCCTCC	TCCTCCTCCTCCACCTCCTCCTCCTCCTCCTCCTCC	7: 80,162,655 (GRCm39)		probably benign	Het
Bmp5	GAGGAGT	G	9: 75,683,657 (GRCm39)		probably benign	Homo
Bpifa6	A	T	2: 153,828,296 (GRCm39)	Q134L	probably benign	Homo
Bpifa6	A	T	2: 153,828,318 (GRCm39)	R141S	probably benign	Homo
Btnl10	AGA	AGAGGA	11: 58,814,755 (GRCm39)		probably benign	Homo
Cacna1a	ACC	ACCGCC	8: 85,365,346 (GRCm39)		probably benign	Het
Cacna1a	ACC	ACCTCC	8: 85,365,355 (GRCm39)		probably benign	Het
Calhm1	TGGCTGTGGCTG	TGGCTGTGGCTGCGGCTGTGGCTG	19: 47,129,701 (GRCm39)		probably benign	Het
Catsper2	TGTC	TGTCGTC	2: 121,228,260 (GRCm39)		probably benign	Homo
Catsper2	C	CTTTTACTTTTTT	2: 121,228,023 (GRCm39)		probably benign	Homo
Catsper2	ATCGTCGTCGTC	ATCGTCGTCGTCGTC	2: 121,228,276 (GRCm39)		probably benign	Het
Catsper2	CAT	CATTAT	2: 121,228,263 (GRCm39)		probably benign	Het
Ccdc170	ACCGCC	ACCGCCGCC	10: 4,511,008 (GRCm39)		probably benign	Het
Ccdc170	AC	ACCTC	10: 4,511,029 (GRCm39)		probably benign	Het
Ccdc170	ACC	ACCGCC	10: 4,511,023 (GRCm39)		probably benign	Het
Ccnk	TTCCCAC	T	12: 108,168,766 (GRCm39)		probably benign	Het
Cdx1	GGGCTGC	GGGCTGCGGCTGC	18: 61,152,939 (GRCm39)		probably benign	Het
Cdx1	GCTGCT	GCTGCTTCTGCT	18: 61,152,941 (GRCm39)		probably benign	Het
Cep112	G	GCTCT	11: 108,316,178 (GRCm39)		probably benign	Het
Cep89	GACT	G	7: 35,109,066 (GRCm39)		probably benign	Het
Cfap46	CCTTCT	CCTTCTTCT	7: 139,218,846 (GRCm39)		probably benign	Homo
Chd4	GC	GCTCCCTC	6: 125,099,094 (GRCm39)		probably benign	Homo
Cluh	GCCTGA	GCCTGAACCTGA	11: 74,560,346 (GRCm39)		probably benign	Het
Cnpy3	CCT	CCTACT	17: 47,047,673 (GRCm39)		probably null	Het
Cntnap1	CCCAGC	CCCAGCACCAGC	11: 101,080,398 (GRCm39)		probably benign	Het
Cntnap1	CCAGCC	CCAGCCTCAGCC	11: 101,080,411 (GRCm39)		probably benign	Het
Cntnap1	GCCCCA	GCCCCACCCCCA	11: 101,080,414 (GRCm39)		probably benign	Het
Cntnap1	A	ACCCCCC	11: 101,080,395 (GRCm39)		probably benign	Het
Col4a3	CGTTTTTTTTTTTTTTTT	C	1: 82,696,627 (GRCm39)		probably null	Het
Cpne1	AGA	AGAGAGA	2: 155,913,945 (GRCm39)		probably null	Homo
Cracdl	C	A	1: 37,664,117 (GRCm39)	E594*	probably null	Homo
Cracdl	A	G	1: 37,664,183 (GRCm39)	S47P	probably damaging	Homo
Cracdl	T	A	1: 37,664,116 (GRCm39)	E594V	probably benign	Homo
Ctsm	AGTG	AGTGGGTG	13: 61,685,650 (GRCm39)		probably null	Homo
Cttnbp2	GCTGCT	GCTGCTTCTGCT	6: 18,367,466 (GRCm39)		probably benign	Het
Cttnbp2	GCTGCT	GCTGCTCCTGCT	6: 18,367,460 (GRCm39)		probably benign	Het
Cul9	TCC	TCCGCC	17: 46,811,776 (GRCm39)		probably benign	Het
Cul9	TCC	TCCCCC	17: 46,811,779 (GRCm39)		probably benign	Het
Cul9	TCC	TCCCCC	17: 46,811,782 (GRCm39)		probably benign	Het
Cul9	CTTC	CTTCTTC	17: 46,811,774 (GRCm39)		probably benign	Het
Cybrd1	GAAT	G	2: 70,968,855 (GRCm39)		probably benign	Homo
Dbr1	AGGAGG	AGGAGGCGGAGG	9: 99,465,742 (GRCm39)		probably benign	Het
Dbr1	AGGAGG	AGGAGGCGGAGG	9: 99,465,745 (GRCm39)		probably benign	Het
Dbr1	AGG	AGGAGGCGG	9: 99,465,754 (GRCm39)		probably benign	Het
Dbr1	GG	GGAGGAAG	9: 99,465,755 (GRCm39)		probably benign	Het
Dcaf8	C	T	1: 172,000,423 (GRCm39)	H194Y	probably damaging	Homo
Dennd10	ACTC	ACTCCTC	19: 60,803,056 (GRCm39)		probably benign	Homo
Dennd10	T	TTCA	19: 60,803,060 (GRCm39)		probably benign	Homo
Dnaaf9	C	CTCG	2: 130,612,673 (GRCm39)		probably benign	Het
Dnaaf9	TCC	TCCCCC	2: 130,612,659 (GRCm39)		probably benign	Het
Dnaaf9	TCC	TCCACC	2: 130,612,662 (GRCm39)		probably benign	Het
Dnajc19	AC	ACGC	3: 34,112,143 (GRCm39)		probably null	Het
Dthd1	GAC	GACTAC	5: 63,000,367 (GRCm39)		probably benign	Homo
Dusp10	G	T	1: 183,769,253 (GRCm39)	C73F	probably damaging	Homo
Eif3a	A	ATTTTT	19: 60,763,729 (GRCm39)		probably benign	Homo
Ermn	CTT	CTTGTT	2: 57,938,092 (GRCm39)		probably benign	Het
Ermn	TC	TCTAC	2: 57,938,100 (GRCm39)		probably benign	Het
Fbxo38	TGCAGC	TGC	18: 62,648,418 (GRCm39)		probably benign	Het
Frem3	CT	CTTGT	8: 81,341,870 (GRCm39)		probably benign	Homo
Fsip2	TT	TTTTTCT	2: 82,814,709 (GRCm39)		probably benign	Het
Fsip2	TTTTT	TTTTTGTTTT	2: 82,814,706 (GRCm39)		probably benign	Het
Gabre	T	TGAGGCC	X: 71,314,028 (GRCm39)		probably benign	Homo
Gabre	AGGCT	AGGCTGCGGCT	X: 71,314,024 (GRCm39)		probably benign	Homo
Gm10800	A	AC	2: 98,497,378 (GRCm39)		probably null	Homo
Gm14393	T	G	2: 174,903,613 (GRCm39)	N98T	probably benign	Het
Gm16503	G	A	4: 147,625,710 (GRCm39)	G68E	unknown	Het
Gm28040	TG	TGGCACCTTTCGAG	1: 133,255,061 (GRCm39)		probably benign	Homo
Gm4340	AGC	AGCCGC	10: 104,031,940 (GRCm39)		probably benign	Het
Gm6309	C	T	5: 146,104,993 (GRCm39)	V307I	probably benign	Het
Golga5	G	A	12: 102,441,919 (GRCm39)		probably null	Homo
Gpatch11	AGGAA	AGGAAGTGGAA	17: 79,149,609 (GRCm39)		probably benign	Het
Gpatch11	GAGGAA	GAGGAATAGGAA	17: 79,149,602 (GRCm39)		probably null	Het
Gpatch11	AGAGGA	AGAGGATGAGGA	17: 79,149,601 (GRCm39)		probably benign	Het
Gpatch11	AAGAGG	AAGAGGCAGAGG	17: 79,149,600 (GRCm39)		probably benign	Het
Gpatch11	GAAGAG	GAAGAGCAAGAG	17: 79,149,599 (GRCm39)		probably benign	Het
H2-K2	GTTT	G	17: 34,216,016 (GRCm39)		probably benign	Homo
Hcn1	GCAGC	GCAGCGACAGC	13: 118,112,344 (GRCm39)		probably benign	Homo
Hoxa10	T	A	6: 52,211,166 (GRCm39)	Q250L	possibly damaging	Homo
Igf1r	C	CTGGAGATGGAGA	7: 67,875,934 (GRCm39)		probably benign	Het
Igf1r	TGGAGC	TGGAGCTGGAGAGGGAGC	7: 67,875,929 (GRCm39)		probably benign	Het
Il17rd	CGG	CGGTGG	14: 26,804,634 (GRCm39)		probably benign	Het
Il2	GG	GGGGCTTGAAGTAG	3: 37,179,978 (GRCm39)		probably benign	Het
Ipo9	TCC	TCCCCC	1: 135,314,019 (GRCm39)		probably benign	Het
Iqcc	T	TGTCAGCCTCCTTGTACCC	4: 129,510,469 (GRCm39)		probably benign	Het
Irag2	CACATTG	CACATTGAGGACATTG	6: 145,119,511 (GRCm39)		probably benign	Homo
Isg20l2	AAG	AAGTAG	3: 87,839,022 (GRCm39)		probably null	Het
Kcng4	G	T	8: 120,360,258 (GRCm39)	Y39*	probably null	Homo
Kmt2b	CCTCCT	CCTCCTACTCCT	7: 30,285,789 (GRCm39)		probably null	Het
Kmt2b	TCCTCC	TCCTCCACCTCC	7: 30,285,791 (GRCm39)		probably benign	Het
Kmt2b	CCTCCT	CCTCCTGCTCCT	7: 30,285,798 (GRCm39)		probably benign	Het
Kmt2b	TCCTCC	TCCTCCCCCTCC	7: 30,285,785 (GRCm39)		probably benign	Het
Kmt2b	CTCCTC	CTCCTCGTCCTC	7: 30,285,787 (GRCm39)		probably benign	Het
Krtap9-3	AC	ACAGGTGCCTC	11: 99,488,830 (GRCm39)		probably benign	Homo
Las1l	A	AGGC	X: 94,984,439 (GRCm39)		probably benign	Het
Las1l	AGG	AGGGGG	X: 94,984,433 (GRCm39)		probably benign	Het
Las1l	GA	GAGAA	X: 94,984,438 (GRCm39)		probably benign	Het
Lce1m	TGCCAC	TGCCACTGCTGCAGCCAC	3: 92,925,455 (GRCm39)		probably benign	Het
Leo1	GGTACCATGCAG	GG	9: 75,357,854 (GRCm39)		probably benign	Het
Lrit3	CATA	CATAAATA	3: 129,597,559 (GRCm39)		probably benign	Homo
Mamld1	GCA	GCAACA	X: 70,162,424 (GRCm39)		probably benign	Het
Mamld1	GCAACA	GCAACAACA	X: 70,162,418 (GRCm39)		probably benign	Het
Mast4	TGG	TGGGGGCGG	13: 102,872,820 (GRCm39)		probably benign	Het
Mast4	GGACAAGCTGTGAGTTGGGGAACCCGGGAG	GG	13: 102,875,755 (GRCm39)		probably null	Homo
Med12l	GCA	GCACCA	3: 59,183,398 (GRCm39)		probably benign	Het
Mn1	CAG	CAGAAG	5: 111,567,568 (GRCm39)		probably benign	Het
Morf4l2	T	C	X: 135,634,371 (GRCm39)	K286E	probably benign	Het
Msantd4	A	T	9: 4,384,937 (GRCm39)	I221F	possibly damaging	Homo
Mup21	TT	TTTTTATATACT	4: 62,067,587 (GRCm39)		probably benign	Het
Nacad	C	CAGGGTA	11: 6,549,763 (GRCm39)		probably benign	Het
Nacad	A	ACCAGGG	11: 6,549,749 (GRCm39)		probably benign	Het
Nacad	TCAGGG	TCAGGGACAGGG	11: 6,549,756 (GRCm39)		probably benign	Het
Nars1	CCACTCAC	CCAC	18: 64,643,516 (GRCm39)		probably benign	Homo
Ndufc2	C	T	7: 97,049,481 (GRCm39)	P29L	probably damaging	Het
Nkx2-6	C	T	14: 69,412,678 (GRCm39)	T282M	probably damaging	Homo
Noc2l	CTG	CTGGTG	4: 156,324,555 (GRCm39)		probably benign	Het
Noc2l	AGGC	AGGCGGC	4: 156,324,549 (GRCm39)		probably benign	Homo
Nolc1	AGC	AGCAGCAGCGGC	19: 46,069,814 (GRCm39)		probably benign	Het
Nolc1	CAG	CAGAAGCAGAAG	19: 46,069,795 (GRCm39)		probably benign	Het
Or10j2	GGGCTGCTTGTGGCAAT	G	1: 173,098,197 (GRCm39)		probably null	Het
Or51f1e	T	TTAC	7: 102,747,516 (GRCm39)		probably benign	Homo
Or51v8	AG	AGAGG	7: 103,320,173 (GRCm39)		probably benign	Homo
Or52b4	A	AAACCG	7: 102,184,888 (GRCm39)		probably null	Homo
Or5af2	T	A	11: 58,708,266 (GRCm39)	V144D	possibly damaging	Homo
Patl2	GCT	GCTTCT	2: 121,956,622 (GRCm39)		probably benign	Het
Patl2	CTG	CTGGTG	2: 121,956,620 (GRCm39)		probably benign	Het
Patl2	C	CTGA	2: 121,956,626 (GRCm39)		probably benign	Het
Patl2	GC	GCTTC	2: 121,956,625 (GRCm39)		probably benign	Het
Pdik1l	ACCACC	ACCACCCCCACC	4: 134,006,817 (GRCm39)		probably benign	Homo
Phc1	TG	TGCTGCGG	6: 122,300,559 (GRCm39)		probably benign	Het
Phf3	ACTGCCGCTCCCGCTCC	AC	1: 30,844,104 (GRCm39)		probably benign	Het
Pick1	TTC	TTCTC	15: 79,140,146 (GRCm39)		probably null	Homo
Piezo1	G	A	8: 123,222,308 (GRCm39)	R503W	probably damaging	Homo
Pik3ap1	AG	AGGGG	19: 41,270,384 (GRCm39)		probably benign	Homo
Pik3c2g	AGAGG	AGAGGGAGG	6: 139,612,652 (GRCm39)		probably null	Homo
Pitrm1	TTTTA	T	13: 6,610,632 (GRCm39)		probably benign	Homo
Pogz	GTAAT	G	3: 94,782,006 (GRCm39)		probably benign	Het
Ppp1r3f	C	A	X: 7,426,575 (GRCm39)	G562V	probably damaging	Homo
Ppp2r5c	G	T	12: 110,507,172 (GRCm39)		probably null	Homo
Prag1	CCGC	CCGCCGC	8: 36,571,037 (GRCm39)		probably benign	Homo
Prr13	CTC	CTCTTC	15: 102,370,611 (GRCm39)		probably benign	Homo
Prr13	CACT	CACTACT	15: 102,370,606 (GRCm39)		probably benign	Homo
Ptms	TCT	TCTCCT	6: 124,891,417 (GRCm39)		probably benign	Homo
Ptpn23	G	T	9: 110,216,701 (GRCm39)	P1052T	probably benign	Homo
Raph1	GG	GGGGG	1: 60,528,426 (GRCm39)		probably benign	Homo
Rpa1	TGCTGCC	T	11: 75,209,345 (GRCm39)		probably benign	Het
Rpgrip1	GGA	GGATGA	14: 52,386,851 (GRCm39)		probably benign	Het
Rpgrip1	GGAAGAAGA	GGA	14: 52,387,001 (GRCm39)		probably benign	Het
Rps19	AGCGG	AG	7: 24,588,421 (GRCm39)		probably benign	Homo
Rsf1	G	GACC	7: 97,229,116 (GRCm39)		probably benign	Homo
Serpina3m	A	G	12: 104,324,882 (GRCm39)		probably null	Homo
Setd1a	TGGTGGTGGT	TGGTGGTGGTGGTGGTGGT	7: 127,384,479 (GRCm39)		probably benign	Homo
Setd1a	TAGTGGTGG	TAGTGGTGGGAGTGGTGG	7: 127,384,488 (GRCm39)		probably benign	Het
Sfswap	ACTCAGCCC	ACTCAGCCCCCTCAGCCC	5: 129,646,815 (GRCm39)		probably benign	Het
Sh3pxd2b	GCCTGT	GCCTGTGCCTGT	11: 32,373,060 (GRCm39)		probably benign	Homo
Sh3pxd2b	CCTGTG	CCTGTGTCTGTG	11: 32,373,055 (GRCm39)		probably benign	Het
Shroom4	GCAGCAACA	GCA	X: 6,536,128 (GRCm39)		probably benign	Het
Six3	GCG	GCGTCG	17: 85,928,786 (GRCm39)		probably benign	Het
Six3	CG	CGGGG	17: 85,928,799 (GRCm39)		probably benign	Het
Skint8	C	T	4: 111,796,099 (GRCm39)	L258F	probably benign	Homo
Smoc2	AGTT	A	17: 14,621,824 (GRCm39)		probably benign	Homo
Smpx	CCCCCA	C	X: 156,503,920 (GRCm39)		probably benign	Homo
Snx1	C	CTTT	9: 66,012,212 (GRCm39)		probably benign	Homo
Snx1	TC	TCTGC	9: 66,012,211 (GRCm39)		probably benign	Homo
Sp110	CT	CTAAT	1: 85,515,210 (GRCm39)		probably benign	Het
Spaca1	CGCTCT	CGCTCTTGCTCT	4: 34,049,849 (GRCm39)		probably benign	Het
Spaca1	GCTCTC	GCTCTCCCTCTC	4: 34,049,844 (GRCm39)		probably benign	Het
Spag17	GGA	GGACGA	3: 99,963,571 (GRCm39)		probably benign	Het
Spag17	AGG	AGGTGG	3: 99,963,570 (GRCm39)		probably benign	Het
Srebf2	G	T	15: 82,069,536 (GRCm39)	A693S	probably damaging	Homo
Sry	T	TGGG	Y: 2,662,841 (GRCm39)		probably benign	Homo
Stard8	AGG	AGGTGG	X: 98,110,119 (GRCm39)		probably benign	Het
Stard8	AGG	AGGTGG	X: 98,110,131 (GRCm39)		probably benign	Het
Stk10	CCCA	C	11: 32,564,520 (GRCm39)		probably benign	Homo
Tap2	ACTG	ACTGCTG	17: 34,424,673 (GRCm39)		probably benign	Homo
Tbc1d5	G	C	17: 51,106,959 (GRCm39)	H532Q	probably benign	Homo
Tbc1d5	C	G	17: 51,106,971 (GRCm39)	Q528H	probably benign	Homo
Tfeb	GCA	GCAACA	17: 48,097,019 (GRCm39)		probably benign	Het
Tmcc1	G	A	6: 116,170,341 (GRCm39)		probably benign	Homo
Tob1	AGC	AGCCGC	11: 94,105,298 (GRCm39)		probably benign	Het
Tpsab1	TTGCACCTCCT	TT	17: 25,562,756 (GRCm39)		probably benign	Het
Trav15-2-dv6-2	GAA	GAATAA	14: 53,887,211 (GRCm39)		probably null	Het
Trav15-2-dv6-2	G	GAAC	14: 53,887,214 (GRCm39)		probably benign	Homo
Trim16	GTGA	GTGATGA	11: 62,711,515 (GRCm39)		probably benign	Homo
Tsbp1	AGC	AGCGGC	17: 34,679,032 (GRCm39)		probably benign	Het
Tsbp1	AGC	AGCGGC	17: 34,679,035 (GRCm39)		probably benign	Het
Tsen2	AGG	AGGCGG	6: 115,537,027 (GRCm39)		probably benign	Homo
Ubtf	TC	TCCGC	11: 102,197,785 (GRCm39)		probably benign	Het
Vmn1r124	G	T	7: 20,993,861 (GRCm39)	Q228K	possibly damaging	Het
Vmn1r71	A	C	7: 10,482,048 (GRCm39)	S147R	probably benign	Homo
Vmn2r99	G	A	17: 19,614,547 (GRCm39)	G756R	probably damaging	Homo
Vps13b	G	T	15: 35,847,103 (GRCm39)	A2629S	probably damaging	Homo
Wdr75	AAATAA	AAA	1: 45,862,564 (GRCm39)		probably benign	Homo
Zfp111	T	G	7: 23,898,462 (GRCm39)	K383T	probably damaging	Homo
Zfp111	A	ATCG	7: 23,899,232 (GRCm39)		probably benign	Homo
Zfp26	C	A	9: 20,349,842 (GRCm39)	A241S	probably benign	Homo
Zfp282	CGG	CGGTGG	6: 47,881,724 (GRCm39)		probably benign	Het
Zfp335	TCC	TCCACC	2: 164,749,398 (GRCm39)		probably benign	Het
Zfp335	CTC	CTCTTC	2: 164,749,394 (GRCm39)		probably benign	Het
Zfp459	A	AGTGG	13: 67,556,395 (GRCm39)		probably null	Homo
Zfp459	TGA	TGAGAGA	13: 67,556,393 (GRCm39)		probably null	Homo
Zfp459	GA	GAGTTA	13: 67,556,394 (GRCm39)		probably null	Homo
Zfp462	ACC	ACCTCAGCCACAGCCGCC	4: 55,009,760 (GRCm39)		probably benign	Het
Zfp462	CC	CCTCAGCCACAGCCATC	4: 55,009,761 (GRCm39)		probably benign	Het
Zfp598	CCACAGGC	CC	17: 24,898,346 (GRCm39)		probably benign	Het
Zfp598	ACCACC	ACCACCCCCACC	17: 24,899,756 (GRCm39)		probably benign	Het
Zfp683	AG	AGGGG	4: 133,786,190 (GRCm39)		probably benign	Homo
Zpld2	TG	TGCCG	4: 133,929,941 (GRCm39)		probably benign	Homo

Other mutations in Kmt2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00436:Kmt2c	APN	5	25,486,259 (GRCm39)	missense	probably damaging	0.99
IGL00694:Kmt2c	APN	5	25,498,159 (GRCm39)	missense	probably damaging	0.99
IGL00780:Kmt2c	APN	5	25,516,049 (GRCm39)	missense	probably benign	0.00
IGL00811:Kmt2c	APN	5	25,579,531 (GRCm39)	missense	possibly damaging	0.75
IGL00885:Kmt2c	APN	5	25,614,169 (GRCm39)	missense	possibly damaging	0.80
IGL00948:Kmt2c	APN	5	25,582,159 (GRCm39)	missense	probably benign	0.08
IGL00959:Kmt2c	APN	5	25,481,227 (GRCm39)	missense	probably damaging	1.00
IGL01022:Kmt2c	APN	5	25,507,699 (GRCm39)	unclassified	probably benign
IGL01146:Kmt2c	APN	5	25,513,510 (GRCm39)	missense	probably damaging	0.96
IGL01154:Kmt2c	APN	5	25,489,397 (GRCm39)	missense	probably damaging	1.00
IGL01434:Kmt2c	APN	5	25,614,306 (GRCm39)	missense	probably damaging	1.00
IGL01464:Kmt2c	APN	5	25,557,242 (GRCm39)	missense	possibly damaging	0.90
IGL01525:Kmt2c	APN	5	25,534,439 (GRCm39)	splice site	probably benign
IGL01530:Kmt2c	APN	5	25,518,498 (GRCm39)	missense	probably benign	0.08
IGL01550:Kmt2c	APN	5	25,486,274 (GRCm39)	missense	probably damaging	1.00
IGL01598:Kmt2c	APN	5	25,478,664 (GRCm39)	makesense	probably null
IGL01598:Kmt2c	APN	5	25,559,769 (GRCm39)	missense	probably damaging	1.00
IGL01608:Kmt2c	APN	5	25,559,809 (GRCm39)	missense	probably damaging	0.97
IGL01663:Kmt2c	APN	5	25,515,668 (GRCm39)	missense	probably damaging	1.00
IGL01707:Kmt2c	APN	5	25,505,096 (GRCm39)	missense	probably damaging	1.00
IGL01714:Kmt2c	APN	5	25,518,398 (GRCm39)	missense	probably benign
IGL01784:Kmt2c	APN	5	25,518,524 (GRCm39)	missense	probably damaging	1.00
IGL01813:Kmt2c	APN	5	25,495,802 (GRCm39)	missense	possibly damaging	0.82
IGL01825:Kmt2c	APN	5	25,515,594 (GRCm39)	missense	probably damaging	1.00
IGL01834:Kmt2c	APN	5	25,600,453 (GRCm39)	missense	probably benign	0.05
IGL02072:Kmt2c	APN	5	25,610,430 (GRCm39)	missense	possibly damaging	0.96
IGL02159:Kmt2c	APN	5	25,516,341 (GRCm39)	missense	probably benign	0.18
IGL02303:Kmt2c	APN	5	25,515,155 (GRCm39)	missense	probably damaging	0.96
IGL02417:Kmt2c	APN	5	25,578,018 (GRCm39)	missense	probably benign
IGL02578:Kmt2c	APN	5	25,571,198 (GRCm39)	intron	probably benign
IGL02811:Kmt2c	APN	5	25,520,026 (GRCm39)	nonsense	probably null
IGL02943:Kmt2c	APN	5	25,495,821 (GRCm39)	missense	probably damaging	1.00
IGL03000:Kmt2c	APN	5	25,489,170 (GRCm39)	missense	probably damaging	1.00
IGL03040:Kmt2c	APN	5	25,515,350 (GRCm39)	missense	probably benign
IGL03076:Kmt2c	APN	5	25,504,149 (GRCm39)	nonsense	probably null
IGL03088:Kmt2c	APN	5	25,504,802 (GRCm39)	missense	probably damaging	0.99
IGL03131:Kmt2c	APN	5	25,520,359 (GRCm39)	missense	probably benign	0.00
FR4304:Kmt2c	UTSW	5	25,520,764 (GRCm39)	small insertion	probably benign
PIT4520001:Kmt2c	UTSW	5	25,520,664 (GRCm39)	missense	probably benign	0.12
PIT4585001:Kmt2c	UTSW	5	25,520,104 (GRCm39)	missense	probably benign	0.21
R0313:Kmt2c	UTSW	5	25,549,928 (GRCm39)	missense	probably damaging	1.00
R0374:Kmt2c	UTSW	5	25,514,706 (GRCm39)	missense	probably damaging	1.00
R0411:Kmt2c	UTSW	5	25,580,955 (GRCm39)	missense	probably damaging	1.00
R0422:Kmt2c	UTSW	5	25,520,662 (GRCm39)	missense	probably benign
R0453:Kmt2c	UTSW	5	25,559,745 (GRCm39)	missense	probably damaging	1.00
R0616:Kmt2c	UTSW	5	25,504,250 (GRCm39)	missense	probably benign
R0619:Kmt2c	UTSW	5	25,503,914 (GRCm39)	missense	probably benign	0.21
R0671:Kmt2c	UTSW	5	25,609,363 (GRCm39)	missense	probably damaging	1.00
R0736:Kmt2c	UTSW	5	25,500,432 (GRCm39)	missense	probably benign
R0745:Kmt2c	UTSW	5	25,564,696 (GRCm39)	splice site	probably null
R0760:Kmt2c	UTSW	5	25,558,315 (GRCm39)	missense	possibly damaging	0.68
R0784:Kmt2c	UTSW	5	25,515,893 (GRCm39)	missense	probably benign	0.00
R0882:Kmt2c	UTSW	5	25,500,605 (GRCm39)	missense	possibly damaging	0.90
R0893:Kmt2c	UTSW	5	25,556,268 (GRCm39)	splice site	probably benign
R0942:Kmt2c	UTSW	5	25,520,301 (GRCm39)	missense	probably benign	0.10
R1110:Kmt2c	UTSW	5	25,519,360 (GRCm39)	missense	probably benign	0.01
R1137:Kmt2c	UTSW	5	25,515,981 (GRCm39)	missense	possibly damaging	0.80
R1255:Kmt2c	UTSW	5	25,556,151 (GRCm39)	missense	probably damaging	1.00
R1300:Kmt2c	UTSW	5	25,610,452 (GRCm39)	missense	probably damaging	0.99
R1497:Kmt2c	UTSW	5	25,519,513 (GRCm39)	missense	possibly damaging	0.80
R1594:Kmt2c	UTSW	5	25,519,876 (GRCm39)	missense	probably benign	0.01
R1611:Kmt2c	UTSW	5	25,564,309 (GRCm39)	critical splice donor site	probably null
R1617:Kmt2c	UTSW	5	25,580,925 (GRCm39)	missense	probably benign	0.01
R1720:Kmt2c	UTSW	5	25,504,182 (GRCm39)	missense	probably benign	0.05
R1723:Kmt2c	UTSW	5	25,520,003 (GRCm39)	missense	probably damaging	1.00
R1724:Kmt2c	UTSW	5	25,520,003 (GRCm39)	missense	probably damaging	1.00
R1726:Kmt2c	UTSW	5	25,520,003 (GRCm39)	missense	probably damaging	1.00
R1736:Kmt2c	UTSW	5	25,495,525 (GRCm39)	missense	probably damaging	1.00
R1778:Kmt2c	UTSW	5	25,577,972 (GRCm39)	missense	probably benign	0.02
R1809:Kmt2c	UTSW	5	25,489,190 (GRCm39)	missense	probably damaging	1.00
R1845:Kmt2c	UTSW	5	25,578,434 (GRCm39)	missense	probably benign	0.45
R1895:Kmt2c	UTSW	5	25,520,152 (GRCm39)	missense	probably benign	0.34
R1946:Kmt2c	UTSW	5	25,520,152 (GRCm39)	missense	probably benign	0.34
R1989:Kmt2c	UTSW	5	25,703,542 (GRCm39)	missense	possibly damaging	0.93
R2039:Kmt2c	UTSW	5	25,534,038 (GRCm39)	missense	possibly damaging	0.53
R2049:Kmt2c	UTSW	5	25,490,077 (GRCm39)	missense	probably damaging	1.00
R2079:Kmt2c	UTSW	5	25,557,278 (GRCm39)	missense	possibly damaging	0.82
R2080:Kmt2c	UTSW	5	25,559,715 (GRCm39)	missense	probably damaging	1.00
R2107:Kmt2c	UTSW	5	25,514,822 (GRCm39)	missense	probably benign	0.01
R2186:Kmt2c	UTSW	5	25,492,110 (GRCm39)	missense	probably damaging	1.00
R2395:Kmt2c	UTSW	5	25,520,150 (GRCm39)	missense	probably benign
R2983:Kmt2c	UTSW	5	25,520,755 (GRCm39)	small deletion	probably benign
R3109:Kmt2c	UTSW	5	25,480,733 (GRCm39)	missense	probably damaging	1.00
R3500:Kmt2c	UTSW	5	25,504,477 (GRCm39)	missense	probably benign	0.02
R3738:Kmt2c	UTSW	5	25,610,381 (GRCm39)	missense	probably benign	0.41
R3809:Kmt2c	UTSW	5	25,614,136 (GRCm39)	missense	possibly damaging	0.87
R4088:Kmt2c	UTSW	5	25,492,711 (GRCm39)	missense	probably benign
R4107:Kmt2c	UTSW	5	25,503,918 (GRCm39)	missense	possibly damaging	0.51
R4212:Kmt2c	UTSW	5	25,552,357 (GRCm39)	critical splice donor site	probably null
R4376:Kmt2c	UTSW	5	25,520,324 (GRCm39)	missense	probably benign	0.00
R4377:Kmt2c	UTSW	5	25,520,324 (GRCm39)	missense	probably benign	0.00
R4383:Kmt2c	UTSW	5	25,556,060 (GRCm39)	missense	possibly damaging	0.77
R4435:Kmt2c	UTSW	5	25,519,875 (GRCm39)	missense	possibly damaging	0.63
R4456:Kmt2c	UTSW	5	25,515,210 (GRCm39)	missense	probably benign
R4461:Kmt2c	UTSW	5	25,504,874 (GRCm39)	missense	probably benign	0.00
R4519:Kmt2c	UTSW	5	25,568,475 (GRCm39)	missense	probably damaging	1.00
R4550:Kmt2c	UTSW	5	25,505,172 (GRCm39)	missense	probably damaging	1.00
R4557:Kmt2c	UTSW	5	25,505,313 (GRCm39)	missense	probably damaging	1.00
R4610:Kmt2c	UTSW	5	25,559,382 (GRCm39)	missense	probably damaging	1.00
R4671:Kmt2c	UTSW	5	25,571,175 (GRCm39)	missense	probably damaging	1.00
R4704:Kmt2c	UTSW	5	25,519,025 (GRCm39)	nonsense	probably null
R4781:Kmt2c	UTSW	5	25,648,823 (GRCm39)	missense	probably damaging	1.00
R4844:Kmt2c	UTSW	5	25,520,111 (GRCm39)	missense	probably benign
R4855:Kmt2c	UTSW	5	25,519,555 (GRCm39)	missense	probably benign	0.00
R4919:Kmt2c	UTSW	5	25,519,393 (GRCm39)	missense	possibly damaging	0.80
R4971:Kmt2c	UTSW	5	25,515,870 (GRCm39)	missense	probably benign	0.00
R4983:Kmt2c	UTSW	5	25,500,509 (GRCm39)	missense	possibly damaging	0.51
R5012:Kmt2c	UTSW	5	25,504,710 (GRCm39)	nonsense	probably null
R5033:Kmt2c	UTSW	5	25,519,706 (GRCm39)	missense	probably benign	0.03
R5093:Kmt2c	UTSW	5	25,614,205 (GRCm39)	missense	probably benign	0.17
R5125:Kmt2c	UTSW	5	25,489,379 (GRCm39)	missense	probably damaging	0.99
R5231:Kmt2c	UTSW	5	25,520,471 (GRCm39)	missense	possibly damaging	0.89
R5254:Kmt2c	UTSW	5	25,519,592 (GRCm39)	missense	probably benign	0.01
R5396:Kmt2c	UTSW	5	25,499,732 (GRCm39)	splice site	probably null
R5415:Kmt2c	UTSW	5	25,519,699 (GRCm39)	missense	probably benign	0.21
R5523:Kmt2c	UTSW	5	25,504,337 (GRCm39)	missense	probably benign	0.00
R5554:Kmt2c	UTSW	5	25,499,608 (GRCm39)	missense	probably damaging	1.00
R5701:Kmt2c	UTSW	5	25,519,015 (GRCm39)	missense	probably benign	0.16
R5762:Kmt2c	UTSW	5	25,515,455 (GRCm39)	missense	probably benign	0.01
R5819:Kmt2c	UTSW	5	25,614,130 (GRCm39)	critical splice donor site	probably null
R5838:Kmt2c	UTSW	5	25,489,469 (GRCm39)	missense	probably damaging	1.00
R5912:Kmt2c	UTSW	5	25,552,467 (GRCm39)	missense	possibly damaging	0.80
R5951:Kmt2c	UTSW	5	25,535,801 (GRCm39)	missense	probably benign	0.15
R5988:Kmt2c	UTSW	5	25,516,118 (GRCm39)	missense	probably benign	0.02
R5999:Kmt2c	UTSW	5	25,489,203 (GRCm39)	missense	probably damaging	1.00
R6104:Kmt2c	UTSW	5	25,504,127 (GRCm39)	missense	probably benign
R6254:Kmt2c	UTSW	5	25,554,872 (GRCm39)	missense	possibly damaging	0.94
R6311:Kmt2c	UTSW	5	25,648,816 (GRCm39)	critical splice donor site	probably null
R6329:Kmt2c	UTSW	5	25,520,600 (GRCm39)	missense	probably benign	0.01
R6347:Kmt2c	UTSW	5	25,515,833 (GRCm39)	missense	possibly damaging	0.54
R6364:Kmt2c	UTSW	5	25,514,634 (GRCm39)	missense	probably null	0.99
R6379:Kmt2c	UTSW	5	25,564,339 (GRCm39)	missense	probably damaging	1.00
R6588:Kmt2c	UTSW	5	25,528,787 (GRCm39)	missense	probably damaging	0.99
R6628:Kmt2c	UTSW	5	25,503,926 (GRCm39)	missense	probably benign
R6733:Kmt2c	UTSW	5	25,614,291 (GRCm39)	missense	probably damaging	1.00
R6787:Kmt2c	UTSW	5	25,480,737 (GRCm39)	splice site	probably null
R6816:Kmt2c	UTSW	5	25,610,530 (GRCm39)	splice site	probably null
R6862:Kmt2c	UTSW	5	25,515,515 (GRCm39)	missense	probably damaging	1.00
R7150:Kmt2c	UTSW	5	25,505,360 (GRCm39)	missense	possibly damaging	0.89
R7220:Kmt2c	UTSW	5	25,549,923 (GRCm39)	missense	probably damaging	1.00
R7250:Kmt2c	UTSW	5	25,514,805 (GRCm39)	missense	probably benign	0.00
R7250:Kmt2c	UTSW	5	25,504,489 (GRCm39)	missense	probably damaging	1.00
R7402:Kmt2c	UTSW	5	25,600,418 (GRCm39)	missense	probably damaging	1.00
R7465:Kmt2c	UTSW	5	25,507,847 (GRCm39)	missense	probably damaging	1.00
R7467:Kmt2c	UTSW	5	25,513,530 (GRCm39)	missense	probably damaging	1.00
R7491:Kmt2c	UTSW	5	25,489,562 (GRCm39)	missense	probably damaging	0.99
R7549:Kmt2c	UTSW	5	25,619,968 (GRCm39)	missense	possibly damaging	0.95
R7637:Kmt2c	UTSW	5	25,520,093 (GRCm39)	missense	probably damaging	1.00
R7652:Kmt2c	UTSW	5	25,520,717 (GRCm39)	missense	probably benign	0.01
R7714:Kmt2c	UTSW	5	25,580,364 (GRCm39)	missense	probably benign
R7838:Kmt2c	UTSW	5	25,499,697 (GRCm39)	missense	possibly damaging	0.57
R7891:Kmt2c	UTSW	5	25,505,109 (GRCm39)	missense	probably damaging	1.00
R7892:Kmt2c	UTSW	5	25,504,814 (GRCm39)	missense	probably benign	0.18
R7895:Kmt2c	UTSW	5	25,578,174 (GRCm39)	missense	possibly damaging	0.65
R7960:Kmt2c	UTSW	5	25,520,194 (GRCm39)	missense	probably benign	0.01
R7974:Kmt2c	UTSW	5	25,505,561 (GRCm39)	missense	probably damaging	1.00
R7978:Kmt2c	UTSW	5	25,564,676 (GRCm39)	missense	probably benign	0.00
R8011:Kmt2c	UTSW	5	25,556,232 (GRCm39)	missense	probably damaging	0.99
R8021:Kmt2c	UTSW	5	25,492,117 (GRCm39)	missense	possibly damaging	0.88
R8022:Kmt2c	UTSW	5	25,486,678 (GRCm39)	missense	possibly damaging	0.83
R8079:Kmt2c	UTSW	5	25,507,730 (GRCm39)	missense	probably damaging	0.98
R8087:Kmt2c	UTSW	5	25,534,250 (GRCm39)	missense	probably damaging	1.00
R8109:Kmt2c	UTSW	5	25,486,382 (GRCm39)	missense	probably damaging	1.00
R8161:Kmt2c	UTSW	5	25,579,562 (GRCm39)	missense	probably benign	0.00
R8169:Kmt2c	UTSW	5	25,559,685 (GRCm39)	missense	probably damaging	1.00
R8206:Kmt2c	UTSW	5	25,519,537 (GRCm39)	missense	probably damaging	0.98
R8218:Kmt2c	UTSW	5	25,488,104 (GRCm39)	missense	probably damaging	1.00
R8223:Kmt2c	UTSW	5	25,529,216 (GRCm39)	missense	possibly damaging	0.89
R8260:Kmt2c	UTSW	5	25,610,514 (GRCm39)	missense	possibly damaging	0.87
R8330:Kmt2c	UTSW	5	25,509,692 (GRCm39)	missense	probably null	1.00
R8355:Kmt2c	UTSW	5	25,559,499 (GRCm39)	critical splice acceptor site	probably null
R8455:Kmt2c	UTSW	5	25,559,499 (GRCm39)	critical splice acceptor site	probably null
R8508:Kmt2c	UTSW	5	25,519,120 (GRCm39)	missense	probably benign	0.34
R8885:Kmt2c	UTSW	5	25,520,077 (GRCm39)	missense	probably benign	0.34
R8907:Kmt2c	UTSW	5	25,514,609 (GRCm39)	missense	probably damaging	1.00
R8924:Kmt2c	UTSW	5	25,503,885 (GRCm39)	missense	probably benign
R8969:Kmt2c	UTSW	5	25,519,387 (GRCm39)	missense	possibly damaging	0.82
R9019:Kmt2c	UTSW	5	25,488,208 (GRCm39)	missense	probably damaging	1.00
R9035:Kmt2c	UTSW	5	25,524,010 (GRCm39)	missense	probably damaging	1.00
R9074:Kmt2c	UTSW	5	25,489,343 (GRCm39)	missense	probably damaging	1.00
R9125:Kmt2c	UTSW	5	25,489,194 (GRCm39)	missense	possibly damaging	0.86
R9130:Kmt2c	UTSW	5	25,516,102 (GRCm39)	missense	probably benign	0.01
R9171:Kmt2c	UTSW	5	25,486,309 (GRCm39)	missense	probably damaging	1.00
R9235:Kmt2c	UTSW	5	25,504,997 (GRCm39)	missense	probably damaging	1.00
R9288:Kmt2c	UTSW	5	25,554,860 (GRCm39)	missense	probably benign	0.34
R9288:Kmt2c	UTSW	5	25,497,907 (GRCm39)	missense	probably damaging	1.00
R9336:Kmt2c	UTSW	5	25,614,165 (GRCm39)	missense	probably benign	0.06
R9443:Kmt2c	UTSW	5	25,515,045 (GRCm39)	missense	probably damaging	1.00
R9481:Kmt2c	UTSW	5	25,497,907 (GRCm39)	missense	probably damaging	1.00
R9481:Kmt2c	UTSW	5	25,554,860 (GRCm39)	missense	probably benign	0.34
R9526:Kmt2c	UTSW	5	25,486,355 (GRCm39)	missense	probably damaging	1.00
R9653:Kmt2c	UTSW	5	25,507,819 (GRCm39)	missense	probably damaging	1.00
R9729:Kmt2c	UTSW	5	25,489,758 (GRCm39)	missense	probably damaging	1.00
R9731:Kmt2c	UTSW	5	25,577,956 (GRCm39)	missense	probably benign	0.18
R9784:Kmt2c	UTSW	5	25,549,959 (GRCm39)	missense	probably damaging	1.00
RF001:Kmt2c	UTSW	5	25,520,773 (GRCm39)	small insertion	probably benign
RF006:Kmt2c	UTSW	5	25,520,770 (GRCm39)	small insertion	probably benign
RF011:Kmt2c	UTSW	5	25,543,457 (GRCm39)	missense	probably damaging	1.00
RF041:Kmt2c	UTSW	5	25,520,773 (GRCm39)	small insertion	probably benign
RF047:Kmt2c	UTSW	5	25,520,758 (GRCm39)	small insertion	probably benign
RF051:Kmt2c	UTSW	5	25,518,477 (GRCm39)	unclassified	probably benign
RF055:Kmt2c	UTSW	5	25,520,770 (GRCm39)	small insertion	probably benign
RF059:Kmt2c	UTSW	5	25,518,477 (GRCm39)	unclassified	probably benign
RF063:Kmt2c	UTSW	5	25,520,762 (GRCm39)	small insertion	probably benign
X0024:Kmt2c	UTSW	5	25,610,483 (GRCm39)	missense	probably benign	0.26
X0027:Kmt2c	UTSW	5	25,535,885 (GRCm39)	missense	possibly damaging	0.90
Z1176:Kmt2c	UTSW	5	25,559,411 (GRCm39)	missense	probably damaging	1.00
Z1177:Kmt2c	UTSW	5	25,571,195 (GRCm39)	critical splice acceptor site	probably null
Z1177:Kmt2c	UTSW	5	25,505,001 (GRCm39)	missense	probably benign	0.00
Z1177:Kmt2c	UTSW	5	25,500,395 (GRCm39)	critical splice donor site	probably null

Predicted Primers

PCR Primer
(F):5'- AGGTTGTGGTTTGACAAACAC -3'
(R):5'- AGGCATCAATAGGACATAATCTGC -3'

Sequencing Primer
(F):5'- GTGGTTTGACAAACACACCATCTG -3'
(R):5'- TAGGACATAATCTGCTACCTACTGAC -3'

Posted On

2018-04-05