Incidental Mutation 'R6248:Dab1'
| ID |
505585 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dab1
|
| Ensembl Gene |
ENSMUSG00000028519 |
| Gene Name |
disabled 1 |
| Synonyms |
C630028C02Rik |
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.859)
|
| Stock # |
R6248 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
103476556-104602041 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 104588948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Valine
at position 524
(A524V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106830]
[ENSMUST00000146078]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106830
AA Change: A524V
PolyPhen 2
Score 0.289 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000102443
Gene: ENSMUSG00000028519
AA Change: A524V
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
254 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
487 |
N/A |
INTRINSIC |
|
low complexity region
|
490 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146078
|
| SMART Domains |
Protein: ENSMUSP00000125033
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
235 |
242 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2232 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 98.0%
- 20x: 94.2%
|
| Validation Efficiency |
100% (92/92) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
PHENOTYPE: Homozygous null display unstable gait and whole-body tremor with a hypoplastic cerebellum devoid of folia, a probable consequence of defective neuronal migration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930523C07Rik |
T |
C |
1: 159,902,978 (GRCm39) |
S83P |
possibly damaging |
Het |
| Actr10 |
A |
T |
12: 70,999,733 (GRCm39) |
E176D |
probably benign |
Het |
| Adcy3 |
G |
A |
12: 4,258,662 (GRCm39) |
|
probably null |
Het |
| AI429214 |
T |
A |
8: 37,461,278 (GRCm39) |
I142N |
probably damaging |
Het |
| Alox12 |
A |
G |
11: 70,143,936 (GRCm39) |
L148S |
probably damaging |
Het |
| Ank3 |
A |
G |
10: 69,809,680 (GRCm39) |
I1147V |
probably benign |
Het |
| Apoc2 |
C |
T |
7: 19,407,493 (GRCm39) |
V12I |
probably benign |
Het |
| Arap3 |
T |
C |
18: 38,124,407 (GRCm39) |
S311G |
probably benign |
Het |
| Arih2 |
G |
T |
9: 108,488,841 (GRCm39) |
H292Q |
probably damaging |
Het |
| Cdc14a |
A |
T |
3: 116,101,843 (GRCm39) |
D312E |
probably benign |
Het |
| Cdh12 |
T |
G |
15: 21,237,800 (GRCm39) |
W12G |
possibly damaging |
Het |
| Cisd2 |
A |
T |
3: 135,114,616 (GRCm39) |
N118K |
probably damaging |
Het |
| Cntnap5b |
A |
G |
1: 99,999,827 (GRCm39) |
Q195R |
probably benign |
Het |
| Cyp2r1 |
A |
G |
7: 114,161,966 (GRCm39) |
|
probably null |
Het |
| Cyp4f37 |
A |
G |
17: 32,848,864 (GRCm39) |
D244G |
possibly damaging |
Het |
| Dido1 |
T |
A |
2: 180,302,048 (GRCm39) |
H1952L |
probably damaging |
Het |
| Dnah10 |
T |
A |
5: 124,871,283 (GRCm39) |
|
probably null |
Het |
| Dnal4 |
T |
A |
15: 79,646,714 (GRCm39) |
M56L |
probably damaging |
Het |
| Emilin2 |
A |
G |
17: 71,581,112 (GRCm39) |
V538A |
probably benign |
Het |
| Eps8l2 |
A |
G |
7: 140,922,015 (GRCm39) |
D31G |
probably damaging |
Het |
| Erp44 |
A |
T |
4: 48,219,479 (GRCm39) |
L112* |
probably null |
Het |
| Etl4 |
C |
T |
2: 20,813,900 (GRCm39) |
T1907I |
possibly damaging |
Het |
| Exoc3 |
A |
G |
13: 74,330,400 (GRCm39) |
F510L |
probably benign |
Het |
| Fam114a2 |
G |
T |
11: 57,383,942 (GRCm39) |
T324K |
possibly damaging |
Het |
| Fer1l4 |
G |
A |
2: 155,888,091 (GRCm39) |
R465C |
probably damaging |
Het |
| Frmd4b |
A |
C |
6: 97,436,173 (GRCm39) |
S2R |
probably benign |
Het |
| Fscn1 |
A |
T |
5: 142,946,778 (GRCm39) |
D192V |
possibly damaging |
Het |
| Gm3486 |
T |
A |
14: 41,206,472 (GRCm39) |
*200C |
probably null |
Het |
| Gusb |
A |
T |
5: 130,029,366 (GRCm39) |
H138Q |
probably benign |
Het |
| Hdac9 |
A |
T |
12: 34,578,293 (GRCm39) |
M4K |
possibly damaging |
Het |
| Hhipl1 |
G |
T |
12: 108,284,964 (GRCm39) |
R439L |
probably benign |
Het |
| Hoxd9 |
A |
G |
2: 74,528,980 (GRCm39) |
E194G |
probably benign |
Het |
| Itgb1 |
A |
G |
8: 129,448,902 (GRCm39) |
S503G |
possibly damaging |
Het |
| Kcnt2 |
T |
A |
1: 140,437,216 (GRCm39) |
C500S |
probably damaging |
Het |
| Kdm7a |
G |
A |
6: 39,123,983 (GRCm39) |
S727L |
possibly damaging |
Het |
| Klhdc4 |
A |
G |
8: 122,540,507 (GRCm39) |
F92L |
probably damaging |
Het |
| Klrb1a |
A |
G |
6: 128,596,137 (GRCm39) |
V62A |
probably damaging |
Het |
| Krit1 |
A |
G |
5: 3,863,032 (GRCm39) |
|
probably null |
Het |
| Krt40 |
A |
G |
11: 99,432,566 (GRCm39) |
I150T |
possibly damaging |
Het |
| Larp4b |
A |
G |
13: 9,208,738 (GRCm39) |
T464A |
probably benign |
Het |
| Lrrc52 |
T |
G |
1: 167,293,964 (GRCm39) |
D107A |
probably damaging |
Het |
| Mapkap1 |
G |
T |
2: 34,408,692 (GRCm39) |
V35F |
probably damaging |
Het |
| Mccc1 |
A |
G |
3: 36,044,313 (GRCm39) |
V171A |
probably damaging |
Het |
| Metap1d |
A |
T |
2: 71,346,104 (GRCm39) |
R222* |
probably null |
Het |
| Mrgpre |
G |
A |
7: 143,334,603 (GRCm39) |
A300V |
probably benign |
Het |
| Mterf1b |
C |
A |
5: 4,246,606 (GRCm39) |
N82K |
probably benign |
Het |
| Myh9 |
C |
T |
15: 77,669,422 (GRCm39) |
W533* |
probably null |
Het |
| Myom2 |
A |
G |
8: 15,148,472 (GRCm39) |
|
probably null |
Het |
| Ncor1 |
G |
A |
11: 62,257,808 (GRCm39) |
P329S |
probably damaging |
Het |
| Nr2f1 |
T |
C |
13: 78,344,611 (GRCm39) |
|
probably benign |
Het |
| Or10x1 |
T |
G |
1: 174,197,236 (GRCm39) |
V251G |
probably benign |
Het |
| Or11a4 |
T |
A |
17: 37,536,451 (GRCm39) |
L145* |
probably null |
Het |
| Or2a57 |
C |
T |
6: 43,212,838 (GRCm39) |
Q99* |
probably null |
Het |
| Or2w6 |
A |
T |
13: 21,843,244 (GRCm39) |
I83N |
possibly damaging |
Het |
| Or52p2 |
T |
C |
7: 102,237,237 (GRCm39) |
T238A |
probably benign |
Het |
| Or6c210 |
A |
G |
10: 129,496,532 (GRCm39) |
I286V |
probably benign |
Het |
| Or6z1 |
A |
T |
7: 6,504,675 (GRCm39) |
C183* |
probably null |
Het |
| Pcdha11 |
T |
C |
18: 37,138,950 (GRCm39) |
L193P |
probably benign |
Het |
| Pcdhb20 |
T |
A |
18: 37,639,285 (GRCm39) |
F604I |
probably damaging |
Het |
| Pde1a |
T |
C |
2: 79,708,545 (GRCm39) |
H291R |
probably damaging |
Het |
| Pfkm |
G |
A |
15: 98,024,260 (GRCm39) |
V423M |
probably damaging |
Het |
| Pira1 |
C |
A |
7: 3,739,337 (GRCm39) |
E510D |
probably benign |
Het |
| Pkd2l1 |
G |
T |
19: 44,146,108 (GRCm39) |
Q149K |
probably benign |
Het |
| Pkhd1l1 |
T |
A |
15: 44,392,955 (GRCm39) |
N1763K |
probably benign |
Het |
| Pla2g4a |
G |
A |
1: 149,748,338 (GRCm39) |
T282I |
probably damaging |
Het |
| Prpf39 |
A |
C |
12: 65,089,528 (GRCm39) |
N89H |
probably damaging |
Het |
| Rad54l2 |
A |
G |
9: 106,587,537 (GRCm39) |
F743L |
probably damaging |
Het |
| Raver2 |
A |
G |
4: 100,991,320 (GRCm39) |
|
probably null |
Het |
| Ric8b |
T |
C |
10: 84,783,709 (GRCm39) |
L189P |
probably damaging |
Het |
| Sccpdh |
T |
C |
1: 179,495,957 (GRCm39) |
F13L |
probably benign |
Het |
| Scd2 |
T |
C |
19: 44,291,448 (GRCm39) |
F296L |
probably damaging |
Het |
| Scg2 |
G |
T |
1: 79,414,023 (GRCm39) |
D233E |
probably benign |
Het |
| Sema5b |
C |
A |
16: 35,448,377 (GRCm39) |
|
probably null |
Het |
| Skint5 |
A |
T |
4: 113,636,286 (GRCm39) |
V644E |
unknown |
Het |
| Slc44a5 |
G |
T |
3: 153,969,678 (GRCm39) |
V612F |
possibly damaging |
Het |
| Snd1 |
C |
T |
6: 28,520,234 (GRCm39) |
R107* |
probably null |
Het |
| Sun5 |
G |
T |
2: 153,702,589 (GRCm39) |
T189K |
probably damaging |
Het |
| Tap1 |
A |
T |
17: 34,412,151 (GRCm39) |
E452V |
probably damaging |
Het |
| Tcam1 |
A |
G |
11: 106,173,652 (GRCm39) |
N32S |
probably benign |
Het |
| Tep1 |
T |
C |
14: 51,067,715 (GRCm39) |
E2167G |
probably damaging |
Het |
| Tm9sf1 |
C |
T |
14: 55,873,827 (GRCm39) |
R557H |
probably damaging |
Het |
| Tmem175 |
T |
C |
5: 108,793,821 (GRCm39) |
V317A |
probably damaging |
Het |
| Tsga13 |
A |
G |
6: 30,874,139 (GRCm39) |
V231A |
probably benign |
Het |
| Tspan12 |
A |
G |
6: 21,799,970 (GRCm39) |
S126P |
probably damaging |
Het |
| Uvrag |
G |
T |
7: 98,637,398 (GRCm39) |
D143E |
probably damaging |
Het |
| Vmn1r230 |
T |
A |
17: 21,067,036 (GRCm39) |
M75K |
possibly damaging |
Het |
| Vmn2r120 |
A |
T |
17: 57,852,287 (GRCm39) |
F10I |
probably benign |
Het |
| Vmn2r57 |
T |
C |
7: 41,049,284 (GRCm39) |
T822A |
probably benign |
Het |
| Vmn2r67 |
T |
C |
7: 84,799,768 (GRCm39) |
Y490C |
probably damaging |
Het |
| Zc3h7b |
T |
A |
15: 81,667,386 (GRCm39) |
W644R |
probably damaging |
Het |
| Zeb1 |
A |
G |
18: 5,766,962 (GRCm39) |
D491G |
probably damaging |
Het |
| Zfp709 |
TCGACG |
TCG |
8: 72,644,552 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
A |
T |
2: 174,486,308 (GRCm39) |
T328S |
possibly damaging |
Het |
|
| Other mutations in Dab1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Dab1
|
APN |
4 |
104,535,950 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00087:Dab1
|
APN |
4 |
104,536,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00328:Dab1
|
APN |
4 |
104,545,635 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL00756:Dab1
|
APN |
4 |
104,585,075 (GRCm39) |
missense |
probably benign |
|
|
IGL02074:Dab1
|
APN |
4 |
104,585,051 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02286:Dab1
|
APN |
4 |
104,537,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02986:Dab1
|
APN |
4 |
104,336,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03008:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03133:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03375:Dab1
|
APN |
4 |
104,538,798 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
LCD18:Dab1
|
UTSW |
4 |
103,903,769 (GRCm39) |
intron |
probably benign |
|
|
R0027:Dab1
|
UTSW |
4 |
104,561,396 (GRCm39) |
intron |
probably benign |
|
|
R0466:Dab1
|
UTSW |
4 |
104,577,747 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0838:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0840:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1086:Dab1
|
UTSW |
4 |
104,185,769 (GRCm39) |
intron |
probably benign |
|
|
R1598:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1640:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1699:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1749:Dab1
|
UTSW |
4 |
104,185,495 (GRCm39) |
intron |
probably benign |
|
|
R1770:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1846:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1847:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1848:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1885:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1986:Dab1
|
UTSW |
4 |
104,470,412 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1990:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2006:Dab1
|
UTSW |
4 |
104,462,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2032:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2034:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2061:Dab1
|
UTSW |
4 |
104,535,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2088:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2089:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2092:Dab1
|
UTSW |
4 |
104,535,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2194:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2361:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2362:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2391:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2424:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2865:Dab1
|
UTSW |
4 |
104,537,343 (GRCm39) |
missense |
probably benign |
|
|
R3118:Dab1
|
UTSW |
4 |
104,537,266 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3716:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3718:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3740:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3742:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3965:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4057:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4393:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4396:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4418:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4607:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4608:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4648:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4693:Dab1
|
UTSW |
4 |
104,536,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4730:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4760:Dab1
|
UTSW |
4 |
104,589,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4927:Dab1
|
UTSW |
4 |
104,561,449 (GRCm39) |
missense |
probably benign |
|
|
R5173:Dab1
|
UTSW |
4 |
104,545,645 (GRCm39) |
splice site |
probably null |
|
|
R5503:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6199:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6200:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6207:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6224:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6227:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6228:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6229:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6246:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6247:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6249:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6250:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6258:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6259:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6260:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6505:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6817:Dab1
|
UTSW |
4 |
104,536,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:Dab1
|
UTSW |
4 |
104,570,987 (GRCm39) |
missense |
|
|
|
R7709:Dab1
|
UTSW |
4 |
104,577,756 (GRCm39) |
nonsense |
probably null |
|
|
R7894:Dab1
|
UTSW |
4 |
104,589,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8142:Dab1
|
UTSW |
4 |
104,535,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8462:Dab1
|
UTSW |
4 |
104,561,404 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8472:Dab1
|
UTSW |
4 |
104,336,439 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9138:Dab1
|
UTSW |
4 |
104,588,929 (GRCm39) |
nonsense |
probably null |
|
|
R9311:Dab1
|
UTSW |
4 |
104,369,463 (GRCm39) |
critical splice donor site |
probably null |
|
|
RF017:Dab1
|
UTSW |
4 |
104,570,849 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Dab1
|
UTSW |
4 |
104,336,429 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Dab1
|
UTSW |
4 |
104,585,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dab1
|
UTSW |
4 |
104,584,937 (GRCm39) |
missense |
probably benign |
0.05 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGGATATAAATGGCTGTGGC -3'
(R):5'- TACAGGAGGCTGAAACTTCCCC -3'
Sequencing Primer
(F):5'- GGATATAAATGGCTGTGGCTTATATG -3'
(R):5'- TGAAACTTCCCCCAGAGGATG -3'
|
| Posted On |
2018-02-28 |
Incidental Mutation