Incidental Mutation 'R5503:Dab1'
| ID |
484486 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dab1
|
| Ensembl Gene |
ENSMUSG00000028519 |
| Gene Name |
disabled 1 |
| Synonyms |
C630028C02Rik |
| MMRRC Submission |
043064-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.859)
|
| Stock # |
R5503 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
103476556-104602041 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 104369461 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 3
(C3S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102439
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106826]
[ENSMUST00000106827]
[ENSMUST00000106830]
[ENSMUST00000143644]
[ENSMUST00000146078]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106826
AA Change: C3S
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000102439
Gene: ENSMUSG00000028519
AA Change: C3S
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
17 |
151 |
3.51e-36 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106827
|
| SMART Domains |
Protein: ENSMUSP00000102440
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106830
|
| SMART Domains |
Protein: ENSMUSP00000102443
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
254 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
487 |
N/A |
INTRINSIC |
|
low complexity region
|
490 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143644
|
| SMART Domains |
Protein: ENSMUSP00000118650
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
160 |
5.54e-25 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146078
|
| SMART Domains |
Protein: ENSMUSP00000125033
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
235 |
242 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.3%
- 3x: 97.4%
- 10x: 95.4%
- 20x: 91.5%
|
| Validation Efficiency |
96% (103/107) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
PHENOTYPE: Homozygous null display unstable gait and whole-body tremor with a hypoplastic cerebellum devoid of folia, a probable consequence of defective neuronal migration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700049A03Rik |
A |
T |
12: 71,211,321 (GRCm39) |
E685V |
possibly damaging |
Het |
| 2700049A03Rik |
G |
T |
12: 71,211,320 (GRCm39) |
E685* |
probably null |
Het |
| Abca6 |
A |
G |
11: 110,109,083 (GRCm39) |
S696P |
probably damaging |
Het |
| Abca9 |
G |
A |
11: 110,032,436 (GRCm39) |
T727M |
probably damaging |
Het |
| Alpk2 |
T |
C |
18: 65,439,312 (GRCm39) |
R1161G |
probably benign |
Het |
| Amy1 |
T |
C |
3: 113,349,709 (GRCm39) |
D487G |
probably benign |
Het |
| Arap2 |
G |
A |
5: 62,787,529 (GRCm39) |
A1409V |
probably damaging |
Het |
| B4galt6 |
C |
A |
18: 20,878,409 (GRCm39) |
|
probably null |
Het |
| Cacna1s |
G |
A |
1: 136,014,480 (GRCm39) |
G382D |
probably damaging |
Het |
| Camk2a |
A |
G |
18: 61,111,072 (GRCm39) |
D87G |
probably damaging |
Het |
| Cdh18 |
A |
G |
15: 23,436,620 (GRCm39) |
Y492C |
probably damaging |
Het |
| Cert1 |
C |
T |
13: 96,679,747 (GRCm39) |
R26C |
possibly damaging |
Het |
| Col18a1 |
C |
T |
10: 76,907,454 (GRCm39) |
G861D |
probably damaging |
Het |
| Crybg1 |
C |
A |
10: 43,874,762 (GRCm39) |
S782I |
probably benign |
Het |
| Csgalnact1 |
G |
A |
8: 68,914,125 (GRCm39) |
L27F |
probably damaging |
Het |
| Dapk1 |
T |
C |
13: 60,873,126 (GRCm39) |
F343L |
probably benign |
Het |
| Dgat1 |
A |
T |
15: 76,386,394 (GRCm39) |
|
probably benign |
Het |
| Dnah11 |
C |
A |
12: 117,844,186 (GRCm39) |
|
probably null |
Het |
| Dsg2 |
T |
A |
18: 20,713,708 (GRCm39) |
Y226* |
probably null |
Het |
| Epg5 |
T |
A |
18: 77,994,422 (GRCm39) |
M351K |
possibly damaging |
Het |
| F13b |
A |
G |
1: 139,450,281 (GRCm39) |
T648A |
probably benign |
Het |
| Fgf17 |
T |
C |
14: 70,874,408 (GRCm39) |
Y127C |
probably damaging |
Het |
| Fkbp15 |
G |
A |
4: 62,246,124 (GRCm39) |
P435S |
probably benign |
Het |
| Gfm1 |
G |
A |
3: 67,361,060 (GRCm39) |
|
probably null |
Het |
| Gigyf1 |
T |
C |
5: 137,521,729 (GRCm39) |
|
probably benign |
Het |
| Gm12830 |
A |
T |
4: 114,678,936 (GRCm39) |
T6S |
unknown |
Het |
| Gm6465 |
A |
T |
5: 11,898,150 (GRCm39) |
N88I |
probably damaging |
Het |
| Gpr18 |
C |
T |
14: 122,149,159 (GRCm39) |
V289I |
probably damaging |
Het |
| Ipp |
G |
T |
4: 116,395,135 (GRCm39) |
E557* |
probably null |
Het |
| Klhl12 |
T |
A |
1: 134,413,653 (GRCm39) |
|
probably null |
Het |
| Klhl38 |
A |
G |
15: 58,185,745 (GRCm39) |
V328A |
possibly damaging |
Het |
| Kndc1 |
A |
G |
7: 139,511,802 (GRCm39) |
T1470A |
probably damaging |
Het |
| Kntc1 |
T |
A |
5: 123,957,939 (GRCm39) |
D2173E |
possibly damaging |
Het |
| Lipi |
T |
C |
16: 75,370,864 (GRCm39) |
K118E |
probably benign |
Het |
| Marf1 |
A |
C |
16: 13,970,095 (GRCm39) |
L208R |
probably damaging |
Het |
| Misp |
G |
A |
10: 79,662,552 (GRCm39) |
R323K |
probably damaging |
Het |
| Mlxip |
T |
A |
5: 123,533,390 (GRCm39) |
M133K |
probably damaging |
Het |
| Mon2 |
A |
T |
10: 122,868,550 (GRCm39) |
M501K |
possibly damaging |
Het |
| Myh2 |
A |
G |
11: 67,064,275 (GRCm39) |
I77V |
probably benign |
Het |
| Napa |
C |
A |
7: 15,849,549 (GRCm39) |
Q254K |
probably benign |
Het |
| Nckap5l |
C |
A |
15: 99,323,503 (GRCm39) |
G1000V |
probably damaging |
Het |
| Neo1 |
A |
T |
9: 58,892,933 (GRCm39) |
S236R |
possibly damaging |
Het |
| Neurl4 |
T |
A |
11: 69,797,194 (GRCm39) |
Y594N |
probably damaging |
Het |
| Nmral1 |
G |
A |
16: 4,533,493 (GRCm39) |
P94L |
probably benign |
Het |
| Notch3 |
A |
T |
17: 32,366,029 (GRCm39) |
I1024N |
probably benign |
Het |
| Nsd1 |
T |
A |
13: 55,393,752 (GRCm39) |
I451K |
probably damaging |
Het |
| Nt5c3b |
T |
C |
11: 100,323,883 (GRCm39) |
D143G |
probably benign |
Het |
| Oplah |
A |
G |
15: 76,189,646 (GRCm39) |
|
probably null |
Het |
| Or13a17 |
A |
C |
7: 140,271,309 (GRCm39) |
M164L |
probably benign |
Het |
| Or2ak4 |
T |
A |
11: 58,649,154 (GRCm39) |
V221E |
probably damaging |
Het |
| Or6b2b |
C |
A |
1: 92,418,918 (GRCm39) |
K186N |
probably benign |
Het |
| Or7d10 |
A |
G |
9: 19,831,675 (GRCm39) |
T57A |
probably benign |
Het |
| Or8b48 |
T |
C |
9: 38,493,368 (GRCm39) |
V265A |
probably benign |
Het |
| Or8g19 |
A |
G |
9: 39,055,780 (GRCm39) |
N128S |
probably benign |
Het |
| Phb2 |
T |
A |
6: 124,689,985 (GRCm39) |
|
probably benign |
Het |
| Plcl2 |
A |
G |
17: 50,816,957 (GRCm39) |
I108V |
probably benign |
Het |
| Plpp6 |
T |
A |
19: 28,942,146 (GRCm39) |
M249K |
probably damaging |
Het |
| Pnpt1 |
G |
A |
11: 29,088,156 (GRCm39) |
G189E |
probably damaging |
Het |
| Pramel17 |
A |
T |
4: 101,692,999 (GRCm39) |
Y334N |
probably benign |
Het |
| Ptprn |
C |
T |
1: 75,228,519 (GRCm39) |
V853M |
probably damaging |
Het |
| Ptprq |
T |
C |
10: 107,524,189 (GRCm39) |
|
probably null |
Het |
| Rai1 |
G |
A |
11: 60,077,279 (GRCm39) |
V448I |
probably benign |
Het |
| Rbm20 |
T |
A |
19: 53,839,785 (GRCm39) |
C925S |
possibly damaging |
Het |
| Rin3 |
C |
A |
12: 102,279,314 (GRCm39) |
P41Q |
probably benign |
Het |
| Rpl31-ps21 |
T |
C |
5: 21,324,505 (GRCm39) |
|
noncoding transcript |
Het |
| Rpl39-ps |
A |
T |
15: 102,543,561 (GRCm39) |
|
noncoding transcript |
Het |
| Rtn4ip1 |
T |
A |
10: 43,783,879 (GRCm39) |
D133E |
probably benign |
Het |
| Ryr1 |
T |
C |
7: 28,768,453 (GRCm39) |
K2839E |
possibly damaging |
Het |
| Septin5 |
T |
C |
16: 18,442,118 (GRCm39) |
K268R |
probably benign |
Het |
| Serpinb6b |
T |
A |
13: 33,161,642 (GRCm39) |
D238E |
possibly damaging |
Het |
| Slc15a2 |
C |
T |
16: 36,582,747 (GRCm39) |
V214M |
probably damaging |
Het |
| Smarca2 |
T |
C |
19: 26,601,336 (GRCm39) |
M18T |
probably damaging |
Het |
| Smarca2 |
C |
A |
19: 26,659,446 (GRCm39) |
T912K |
possibly damaging |
Het |
| Smdt1 |
A |
T |
15: 82,232,101 (GRCm39) |
R46S |
possibly damaging |
Het |
| Spa17 |
A |
C |
9: 37,523,273 (GRCm39) |
F5V |
probably damaging |
Het |
| Spag17 |
A |
G |
3: 99,934,560 (GRCm39) |
E614G |
possibly damaging |
Het |
| Sstr4 |
CGAGGAGGAGGAGGA |
CGAGGAGGAGGAGGAGGA |
2: 148,237,471 (GRCm39) |
|
probably benign |
Het |
| Tlr1 |
A |
T |
5: 65,083,635 (GRCm39) |
V314D |
probably damaging |
Het |
| Trappc8 |
A |
T |
18: 20,969,957 (GRCm39) |
L1011Q |
probably benign |
Het |
| Tsga10 |
A |
G |
1: 37,800,028 (GRCm39) |
*691Q |
probably null |
Het |
| Vav1 |
A |
T |
17: 57,610,079 (GRCm39) |
K420* |
probably null |
Het |
| Vmn1r174 |
C |
G |
7: 23,453,562 (GRCm39) |
T76R |
probably benign |
Het |
| Vmn2r116 |
A |
G |
17: 23,605,778 (GRCm39) |
E230G |
probably benign |
Het |
| Vps13b |
A |
G |
15: 35,452,312 (GRCm39) |
T637A |
probably damaging |
Het |
| Zbtb7a |
A |
G |
10: 80,980,631 (GRCm39) |
E275G |
probably damaging |
Het |
| Zfp280b |
A |
G |
10: 75,875,296 (GRCm39) |
|
probably null |
Het |
| Zfp763 |
A |
G |
17: 33,238,507 (GRCm39) |
Y213H |
possibly damaging |
Het |
| Zfp78 |
T |
A |
7: 6,381,528 (GRCm39) |
W161R |
probably benign |
Het |
|
| Other mutations in Dab1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Dab1
|
APN |
4 |
104,535,950 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00087:Dab1
|
APN |
4 |
104,536,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00328:Dab1
|
APN |
4 |
104,545,635 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL00756:Dab1
|
APN |
4 |
104,585,075 (GRCm39) |
missense |
probably benign |
|
|
IGL02074:Dab1
|
APN |
4 |
104,585,051 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02286:Dab1
|
APN |
4 |
104,537,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02986:Dab1
|
APN |
4 |
104,336,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03008:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03133:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03375:Dab1
|
APN |
4 |
104,538,798 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
LCD18:Dab1
|
UTSW |
4 |
103,903,769 (GRCm39) |
intron |
probably benign |
|
|
R0027:Dab1
|
UTSW |
4 |
104,561,396 (GRCm39) |
intron |
probably benign |
|
|
R0466:Dab1
|
UTSW |
4 |
104,577,747 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0838:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0840:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1086:Dab1
|
UTSW |
4 |
104,185,769 (GRCm39) |
intron |
probably benign |
|
|
R1598:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1640:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1699:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1749:Dab1
|
UTSW |
4 |
104,185,495 (GRCm39) |
intron |
probably benign |
|
|
R1770:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1846:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1847:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1848:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1885:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1986:Dab1
|
UTSW |
4 |
104,470,412 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1990:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2006:Dab1
|
UTSW |
4 |
104,462,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2032:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2034:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2061:Dab1
|
UTSW |
4 |
104,535,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2088:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2089:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2092:Dab1
|
UTSW |
4 |
104,535,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2194:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2361:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2362:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2391:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2424:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2865:Dab1
|
UTSW |
4 |
104,537,343 (GRCm39) |
missense |
probably benign |
|
|
R3118:Dab1
|
UTSW |
4 |
104,537,266 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3716:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3718:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3740:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3742:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3965:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4057:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4393:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4396:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4418:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4607:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4608:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4648:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4693:Dab1
|
UTSW |
4 |
104,536,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4730:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4760:Dab1
|
UTSW |
4 |
104,589,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4927:Dab1
|
UTSW |
4 |
104,561,449 (GRCm39) |
missense |
probably benign |
|
|
R5173:Dab1
|
UTSW |
4 |
104,545,645 (GRCm39) |
splice site |
probably null |
|
|
R6199:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6200:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6207:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6224:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6227:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6228:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6229:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6246:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6247:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6248:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6249:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6250:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6258:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6259:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6260:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6505:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6817:Dab1
|
UTSW |
4 |
104,536,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:Dab1
|
UTSW |
4 |
104,570,987 (GRCm39) |
missense |
|
|
|
R7709:Dab1
|
UTSW |
4 |
104,577,756 (GRCm39) |
nonsense |
probably null |
|
|
R7894:Dab1
|
UTSW |
4 |
104,589,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8142:Dab1
|
UTSW |
4 |
104,535,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8462:Dab1
|
UTSW |
4 |
104,561,404 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8472:Dab1
|
UTSW |
4 |
104,336,439 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9138:Dab1
|
UTSW |
4 |
104,588,929 (GRCm39) |
nonsense |
probably null |
|
|
R9311:Dab1
|
UTSW |
4 |
104,369,463 (GRCm39) |
critical splice donor site |
probably null |
|
|
RF017:Dab1
|
UTSW |
4 |
104,570,849 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Dab1
|
UTSW |
4 |
104,336,429 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Dab1
|
UTSW |
4 |
104,585,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dab1
|
UTSW |
4 |
104,584,937 (GRCm39) |
missense |
probably benign |
0.05 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGCAGTTCAACAGAATTATCAGG -3'
(R):5'- AGGGCTGAAAATACTTGCCAC -3'
Sequencing Primer
(F):5'- GAATGTTCCGTGTGGGGCTC -3'
(R):5'- ACAAAGGCTGTGGTGACTGTC -3'
|
| Posted On |
2017-07-21 |
Incidental Mutation