Incidental Mutation 'LCD18:Ptprk'
| ID |
478201 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprk
|
| Ensembl Gene |
ENSMUSG00000019889 |
| Gene Name |
protein tyrosine phosphatase receptor type K |
| Synonyms |
RPTPkappa, PTPk |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
LCD18 (G1)
|
| Quality Score |
999 |
|
Status
|
Validated
|
| Chromosome |
10 |
| Chromosomal Location |
27950816-28473393 bp(+) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
T to C
at 28450983 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151986
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166468]
[ENSMUST00000218276]
[ENSMUST00000218359]
|
| AlphaFold |
P35822 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166468
|
| SMART Domains |
Protein: ENSMUSP00000126279
Gene: ENSMUSG00000019889
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
MAM
|
30 |
193 |
1.61e-73 |
SMART |
|
IG
|
200 |
288 |
2.16e-8 |
SMART |
|
FN3
|
290 |
373 |
1.48e-4 |
SMART |
|
FN3
|
389 |
475 |
4.24e1 |
SMART |
|
FN3
|
491 |
579 |
3.32e-7 |
SMART |
|
transmembrane domain
|
753 |
774 |
N/A |
INTRINSIC |
|
PTPc
|
898 |
1161 |
3.56e-132 |
SMART |
|
PTPc
|
1190 |
1455 |
2.68e-86 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000218276
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000218359
|
| Coding Region Coverage |
- 1x: 0.0%
- 3x: 0.0%
- 10x: 0.0%
- 20x: 0.0%
|
| Validation Efficiency |
88% (169/191) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A330008L17Rik |
A |
G |
8: 100,450,057 (GRCm39) |
|
noncoding transcript |
Het |
| Aff2 |
C |
A |
X: 68,791,141 (GRCm39) |
|
probably benign |
Het |
| Aldh1a1 |
C |
A |
19: 20,604,010 (GRCm39) |
|
probably benign |
Het |
| Anxa7 |
C |
T |
14: 20,519,479 (GRCm39) |
G113E |
probably damaging |
Het |
| Apba2 |
A |
T |
7: 64,271,908 (GRCm39) |
|
probably benign |
Het |
| Apc2 |
G |
C |
10: 80,135,808 (GRCm39) |
|
probably benign |
Het |
| App |
C |
G |
16: 84,822,300 (GRCm39) |
|
probably benign |
Het |
| Asic2 |
C |
A |
11: 80,876,570 (GRCm39) |
|
probably benign |
Het |
| Btk |
T |
C |
X: 133,479,574 (GRCm39) |
|
probably benign |
Het |
| Car12 |
C |
A |
9: 66,668,958 (GRCm39) |
|
probably benign |
Het |
| Ccdc121 |
GAGAAG |
GAG |
5: 31,644,717 (GRCm39) |
|
probably benign |
Het |
| Ccdc191 |
G |
A |
16: 43,742,164 (GRCm39) |
|
probably benign |
Het |
| Ccdc34 |
N |
|
2: 110,016,318 (GRCm38) |
|
probably benign |
Het |
| Cd164 |
G |
T |
10: 41,397,922 (GRCm39) |
A59S |
probably benign |
Het |
| Cd22 |
C |
T |
7: 30,577,507 (GRCm39) |
R2H |
possibly damaging |
Het |
| Cdv3 |
C |
A |
9: 103,242,553 (GRCm39) |
|
probably benign |
Het |
| Cdv3 |
A |
T |
9: 103,242,542 (GRCm39) |
|
probably benign |
Het |
| Celf2 |
N |
|
2: 6,779,076 (GRCm38) |
|
probably benign |
Het |
| Cfap299 |
G |
A |
5: 98,855,367 (GRCm39) |
|
probably benign |
Het |
| Clec18a |
C |
A |
8: 111,802,768 (GRCm39) |
|
probably benign |
Het |
| Cnpy3 |
GGATGGAT |
GGATAGATAGATAGATAGATGGAT |
17: 47,048,462 (GRCm39) |
|
probably benign |
Het |
| Cntn4 |
A |
G |
6: 106,530,901 (GRCm39) |
|
probably benign |
Het |
| Cntnap5c |
G |
C |
17: 58,469,155 (GRCm39) |
|
probably benign |
Het |
| Col2a1 |
C |
A |
15: 97,886,862 (GRCm39) |
|
probably null |
Het |
| Cpne3 |
G |
T |
4: 19,563,382 (GRCm39) |
|
probably benign |
Het |
| Cracd |
GGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG |
GGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG |
5: 76,806,589 (GRCm39) |
|
probably benign |
Het |
| Dab1 |
T |
G |
4: 103,903,769 (GRCm39) |
|
probably benign |
Het |
| Dapp1 |
G |
A |
3: 137,645,161 (GRCm39) |
|
probably benign |
Het |
| Dcc |
G |
A |
18: 72,430,518 (GRCm39) |
|
probably benign |
Het |
| Dcun1d1 |
GAAAAAAAAA |
GAAAAAAAAAA |
3: 35,992,154 (GRCm39) |
|
probably benign |
Het |
| Dennd1b |
G |
A |
1: 139,042,502 (GRCm39) |
|
probably benign |
Het |
| Dhdds |
TAA |
TA |
4: 133,697,674 (GRCm39) |
|
probably benign |
Het |
| Dnah12 |
G |
T |
14: 26,571,342 (GRCm39) |
G2817V |
probably damaging |
Het |
| Dnm3 |
CATATATATATATATATATATATA |
CATATATATATATATATATATA |
1: 162,234,130 (GRCm39) |
|
probably benign |
Het |
| Dock10 |
N |
|
1: 80,716,623 (GRCm38) |
|
probably benign |
Het |
| Dusp10 |
G |
T |
1: 183,769,253 (GRCm39) |
C73F |
probably damaging |
Het |
| Fgf20 |
A |
C |
8: 40,745,359 (GRCm39) |
|
probably benign |
Het |
| Ftsj3 |
G |
T |
11: 106,140,885 (GRCm39) |
|
probably benign |
Het |
| Gls |
T |
G |
1: 52,222,526 (GRCm39) |
|
probably benign |
Het |
| Gm12130 |
T |
C |
11: 38,397,750 (GRCm39) |
|
noncoding transcript |
Het |
| Gm14936 |
G |
A |
X: 111,908,447 (GRCm39) |
|
noncoding transcript |
Het |
| Gm16630 |
C |
T |
6: 48,118,203 (GRCm39) |
|
noncoding transcript |
Het |
| Gm22194 |
AGTGTGTGTGTGTGTGTGTGTGTGTGTGTG |
AGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG |
10: 11,816,707 (GRCm39) |
|
noncoding transcript |
Het |
| Gm26917 |
C |
G |
17: 40,154,862 (GRCm39) |
|
noncoding transcript |
Het |
| Gm35048 |
GACACACACACACACACACACACACACACACACACACAC |
GACACACACACACACACACACACACACACACACACAC |
1: 90,449,248 (GRCm39) |
|
noncoding transcript |
Het |
| Gm37311 |
G |
A |
16: 77,415,169 (GRCm39) |
|
noncoding transcript |
Het |
| Gm37928 |
AACACACACACACACACACACACACACACACACA |
AACACACACACACACACACACACACACACACACACA |
3: 118,328,206 (GRCm39) |
|
noncoding transcript |
Het |
| Gm4302 |
T |
C |
10: 100,177,306 (GRCm39) |
W197R |
probably benign |
Het |
| H2-Q4 |
G |
A |
17: 35,599,381 (GRCm39) |
D155N |
probably damaging |
Het |
| H2-T23 |
T |
C |
17: 36,342,108 (GRCm39) |
|
probably benign |
Het |
| Hgs |
CTTTTTTT |
CTTTTTT |
11: 120,360,404 (GRCm39) |
|
probably benign |
Het |
| Ighv5-9 |
C |
T |
12: 113,625,497 (GRCm39) |
S82N |
probably benign |
Het |
| Il1rap |
C |
A |
16: 26,450,343 (GRCm39) |
|
probably benign |
Het |
| Inhbc |
N |
|
10: 127,367,140 (GRCm38) |
|
probably benign |
Het |
| Inpp4b |
C |
T |
8: 82,419,639 (GRCm39) |
|
probably benign |
Het |
| Kars1 |
N |
|
8: 111,993,708 (GRCm38) |
|
probably benign |
Het |
| Kcng4 |
G |
T |
8: 120,360,258 (GRCm39) |
Y39* |
probably null |
Het |
| Kcnh7 |
A |
G |
2: 62,880,143 (GRCm39) |
|
probably benign |
Het |
| Klhl1 |
G |
C |
14: 96,555,166 (GRCm39) |
|
probably benign |
Het |
| Lrch1 |
C |
T |
14: 75,142,461 (GRCm39) |
|
probably benign |
Het |
| Lrp1b |
G |
C |
2: 42,127,574 (GRCm39) |
|
probably benign |
Het |
| Lsm8 |
G |
A |
6: 18,844,315 (GRCm39) |
|
probably benign |
Het |
| Lsm8 |
G |
A |
6: 18,854,320 (GRCm39) |
|
probably benign |
Het |
| Magi2 |
T |
C |
5: 20,159,509 (GRCm39) |
|
probably benign |
Het |
| Matcap2 |
N |
|
9: 22,442,083 (GRCm38) |
|
probably benign |
Het |
| Mef2c |
G |
A |
13: 83,753,942 (GRCm39) |
|
probably benign |
Het |
| Mei4 |
A |
G |
9: 82,069,012 (GRCm39) |
|
probably benign |
Het |
| Mid1 |
T |
A |
X: 168,788,560 (GRCm39) |
|
probably benign |
Het |
| Mndal |
G |
C |
1: 173,707,784 (GRCm39) |
|
probably benign |
Het |
| Mpped2 |
C |
A |
2: 106,551,773 (GRCm39) |
|
probably benign |
Het |
| Mtarc2 |
TAGGCAGCCAATCAGAGCACTGCCTCTCAGCGCCAGGCAGCCAATCAGAGCACTGCCTCTCAGCGCCAGGCA |
TAGGCAGCCAATCAGAGCACTGCCTCTCAGCGCCAGGCA |
1: 184,554,985 (GRCm39) |
|
probably benign |
Het |
| Mtf1 |
A |
G |
4: 124,723,109 (GRCm39) |
|
probably benign |
Het |
| Mxd1 |
T |
C |
6: 86,644,388 (GRCm39) |
|
probably benign |
Het |
| Nbea |
G |
T |
3: 55,608,948 (GRCm39) |
|
probably benign |
Het |
| Ncor1 |
N |
|
11: 62,419,782 (GRCm38) |
|
probably benign |
Het |
| Nox4 |
A |
G |
7: 86,892,275 (GRCm39) |
|
probably benign |
Het |
| Ocln |
C |
T |
13: 100,657,075 (GRCm39) |
|
probably benign |
Het |
| Ofcc1 |
G |
A |
13: 40,246,443 (GRCm39) |
|
probably benign |
Het |
| Or5af2 |
T |
A |
11: 58,708,266 (GRCm39) |
V144D |
possibly damaging |
Het |
| Paics |
N |
|
5: 76,956,744 (GRCm38) |
|
probably null |
Het |
| Paqr8 |
G |
T |
1: 20,984,882 (GRCm39) |
|
probably benign |
Het |
| Pate9 |
T |
C |
9: 36,444,849 (GRCm39) |
|
probably benign |
Het |
| Pdss1 |
C |
T |
2: 22,790,980 (GRCm39) |
|
probably benign |
Het |
| Piezo1 |
G |
A |
8: 123,222,308 (GRCm39) |
R503W |
probably damaging |
Het |
| Pkhd1 |
G |
A |
1: 20,681,638 (GRCm39) |
|
probably benign |
Het |
| Ppp1r3f |
C |
A |
X: 7,426,575 (GRCm39) |
G562V |
probably damaging |
Het |
| Prr16 |
C |
T |
18: 51,333,396 (GRCm39) |
|
probably benign |
Het |
| Prss38 |
T |
G |
11: 59,266,467 (GRCm39) |
|
probably benign |
Het |
| Prxl2c |
G |
A |
13: 64,435,099 (GRCm39) |
|
probably benign |
Het |
| Pum1 |
N |
|
4: 130,730,549 (GRCm38) |
|
probably benign |
Het |
| Rabgef1 |
N |
|
5: 130,187,586 (GRCm38) |
|
probably null |
Het |
| Rgs16 |
G |
A |
1: 153,619,976 (GRCm39) |
|
probably benign |
Het |
| Riok3 |
G |
T |
18: 12,263,039 (GRCm39) |
|
probably benign |
Het |
| Rn18s-rs5 |
T |
C |
17: 40,159,446 (GRCm39) |
|
noncoding transcript |
Het |
| Robo2 |
N |
|
16: 74,055,954 (GRCm38) |
|
probably benign |
Het |
| Rps6ka3 |
A |
G |
X: 158,062,211 (GRCm39) |
|
probably benign |
Het |
| Rptn |
T |
A |
3: 93,304,848 (GRCm39) |
L727Q |
probably benign |
Het |
| Slc25a46 |
C |
A |
18: 31,730,366 (GRCm39) |
|
probably benign |
Het |
| Spata31f1e |
T |
C |
4: 42,792,885 (GRCm39) |
T416A |
probably benign |
Het |
| Spsb1 |
C |
T |
4: 150,036,943 (GRCm39) |
|
probably benign |
Het |
| Tbc1d19 |
A |
C |
5: 53,974,051 (GRCm39) |
|
probably benign |
Het |
| Trav7-4 |
C |
T |
14: 53,698,975 (GRCm39) |
L41F |
probably benign |
Het |
| Trip12 |
N |
|
1: 84,754,482 (GRCm38) |
|
probably benign |
Het |
| Ttc13 |
G |
A |
8: 125,402,605 (GRCm39) |
|
probably benign |
Het |
| Ttll6 |
C |
T |
11: 96,046,084 (GRCm39) |
|
probably benign |
Het |
| Unc5b |
C |
G |
10: 60,621,950 (GRCm39) |
|
probably benign |
Het |
| Vmn2r87 |
C |
T |
10: 130,314,583 (GRCm39) |
M334I |
probably benign |
Het |
| Vps13b |
G |
T |
15: 35,847,103 (GRCm39) |
A2629S |
probably damaging |
Het |
| Wars2 |
N |
|
3: 99,214,774 (GRCm38) |
|
probably null |
Het |
| Zdhhc3 |
AACACACACACACACACACACACACACACACAC |
AACACACACACACACACACACACACACACACACAC |
9: 122,912,087 (GRCm39) |
|
probably benign |
Het |
| Zfp26 |
C |
A |
9: 20,349,842 (GRCm39) |
A241S |
probably benign |
Het |
| Zfp442 |
C |
T |
2: 150,261,768 (GRCm39) |
|
probably benign |
Het |
| Zfp808 |
C |
T |
13: 62,314,465 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Ptprk |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00310:Ptprk
|
APN |
10 |
28,212,506 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00533:Ptprk
|
APN |
10 |
28,461,971 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01062:Ptprk
|
APN |
10 |
28,456,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01295:Ptprk
|
APN |
10 |
28,351,174 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL01372:Ptprk
|
APN |
10 |
28,445,923 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01452:Ptprk
|
APN |
10 |
28,450,913 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01829:Ptprk
|
APN |
10 |
28,449,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01861:Ptprk
|
APN |
10 |
28,259,441 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01955:Ptprk
|
APN |
10 |
28,471,861 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02263:Ptprk
|
APN |
10 |
27,951,110 (GRCm39) |
missense |
unknown |
|
|
IGL02489:Ptprk
|
APN |
10 |
28,259,468 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02697:Ptprk
|
APN |
10 |
28,451,614 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02713:Ptprk
|
APN |
10 |
28,468,807 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02943:Ptprk
|
APN |
10 |
28,351,172 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL03240:Ptprk
|
APN |
10 |
28,368,957 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03373:Ptprk
|
APN |
10 |
28,442,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Ptprk
|
UTSW |
10 |
28,462,015 (GRCm39) |
missense |
probably benign |
|
|
R0010:Ptprk
|
UTSW |
10 |
28,461,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0021:Ptprk
|
UTSW |
10 |
28,468,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0021:Ptprk
|
UTSW |
10 |
28,468,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0035:Ptprk
|
UTSW |
10 |
28,139,504 (GRCm39) |
nonsense |
probably null |
|
|
R0035:Ptprk
|
UTSW |
10 |
28,139,504 (GRCm39) |
nonsense |
probably null |
|
|
R0053:Ptprk
|
UTSW |
10 |
28,351,105 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0063:Ptprk
|
UTSW |
10 |
28,139,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Ptprk
|
UTSW |
10 |
28,139,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0244:Ptprk
|
UTSW |
10 |
28,082,221 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0281:Ptprk
|
UTSW |
10 |
28,449,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0387:Ptprk
|
UTSW |
10 |
28,230,625 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0480:Ptprk
|
UTSW |
10 |
28,461,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0480:Ptprk
|
UTSW |
10 |
28,461,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Ptprk
|
UTSW |
10 |
28,451,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Ptprk
|
UTSW |
10 |
27,951,132 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0684:Ptprk
|
UTSW |
10 |
28,359,294 (GRCm39) |
splice site |
probably benign |
|
|
R1073:Ptprk
|
UTSW |
10 |
28,372,943 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1377:Ptprk
|
UTSW |
10 |
28,462,022 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1422:Ptprk
|
UTSW |
10 |
28,351,276 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1482:Ptprk
|
UTSW |
10 |
28,139,512 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1532:Ptprk
|
UTSW |
10 |
28,461,626 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1576:Ptprk
|
UTSW |
10 |
28,427,647 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1618:Ptprk
|
UTSW |
10 |
28,369,166 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1654:Ptprk
|
UTSW |
10 |
28,259,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1701:Ptprk
|
UTSW |
10 |
28,342,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1747:Ptprk
|
UTSW |
10 |
28,230,688 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R2033:Ptprk
|
UTSW |
10 |
28,468,763 (GRCm39) |
unclassified |
probably benign |
|
|
R2059:Ptprk
|
UTSW |
10 |
28,442,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2076:Ptprk
|
UTSW |
10 |
28,465,364 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2164:Ptprk
|
UTSW |
10 |
28,436,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2260:Ptprk
|
UTSW |
10 |
28,082,145 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2394:Ptprk
|
UTSW |
10 |
28,427,713 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2432:Ptprk
|
UTSW |
10 |
28,468,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2437:Ptprk
|
UTSW |
10 |
28,230,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ptprk
|
UTSW |
10 |
28,351,074 (GRCm39) |
splice site |
probably benign |
|
|
R3037:Ptprk
|
UTSW |
10 |
28,456,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Ptprk
|
UTSW |
10 |
28,468,822 (GRCm39) |
missense |
probably benign |
|
|
R3162:Ptprk
|
UTSW |
10 |
28,468,822 (GRCm39) |
missense |
probably benign |
|
|
R3687:Ptprk
|
UTSW |
10 |
28,349,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3722:Ptprk
|
UTSW |
10 |
28,259,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3892:Ptprk
|
UTSW |
10 |
28,139,617 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3963:Ptprk
|
UTSW |
10 |
28,427,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4077:Ptprk
|
UTSW |
10 |
28,139,508 (GRCm39) |
missense |
probably benign |
|
|
R4079:Ptprk
|
UTSW |
10 |
28,139,508 (GRCm39) |
missense |
probably benign |
|
|
R4112:Ptprk
|
UTSW |
10 |
28,351,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4255:Ptprk
|
UTSW |
10 |
28,082,241 (GRCm39) |
missense |
probably benign |
0.14 |
|
R4523:Ptprk
|
UTSW |
10 |
28,342,048 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4651:Ptprk
|
UTSW |
10 |
28,139,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4652:Ptprk
|
UTSW |
10 |
28,139,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4828:Ptprk
|
UTSW |
10 |
28,436,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ptprk
|
UTSW |
10 |
28,456,480 (GRCm39) |
nonsense |
probably null |
|
|
R4883:Ptprk
|
UTSW |
10 |
28,464,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5004:Ptprk
|
UTSW |
10 |
28,462,059 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5013:Ptprk
|
UTSW |
10 |
28,427,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5092:Ptprk
|
UTSW |
10 |
28,468,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5126:Ptprk
|
UTSW |
10 |
28,451,640 (GRCm39) |
splice site |
probably null |
|
|
R5183:Ptprk
|
UTSW |
10 |
28,351,232 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5264:Ptprk
|
UTSW |
10 |
28,461,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5304:Ptprk
|
UTSW |
10 |
28,468,050 (GRCm39) |
splice site |
probably null |
|
|
R5330:Ptprk
|
UTSW |
10 |
28,463,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5474:Ptprk
|
UTSW |
10 |
28,372,926 (GRCm39) |
nonsense |
probably null |
|
|
R5516:Ptprk
|
UTSW |
10 |
28,372,926 (GRCm39) |
nonsense |
probably null |
|
|
R5796:Ptprk
|
UTSW |
10 |
28,259,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5843:Ptprk
|
UTSW |
10 |
28,369,060 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5952:Ptprk
|
UTSW |
10 |
28,461,671 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6065:Ptprk
|
UTSW |
10 |
28,351,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6226:Ptprk
|
UTSW |
10 |
28,440,099 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6264:Ptprk
|
UTSW |
10 |
28,442,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6638:Ptprk
|
UTSW |
10 |
28,471,807 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6843:Ptprk
|
UTSW |
10 |
28,467,978 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6860:Ptprk
|
UTSW |
10 |
28,210,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6869:Ptprk
|
UTSW |
10 |
28,349,055 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7214:Ptprk
|
UTSW |
10 |
28,450,905 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7307:Ptprk
|
UTSW |
10 |
28,465,004 (GRCm39) |
nonsense |
probably null |
|
|
R7349:Ptprk
|
UTSW |
10 |
28,468,834 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7442:Ptprk
|
UTSW |
10 |
28,450,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7585:Ptprk
|
UTSW |
10 |
28,436,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7661:Ptprk
|
UTSW |
10 |
28,342,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7694:Ptprk
|
UTSW |
10 |
28,465,366 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7740:Ptprk
|
UTSW |
10 |
28,372,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7810:Ptprk
|
UTSW |
10 |
28,468,853 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7831:Ptprk
|
UTSW |
10 |
28,444,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7836:Ptprk
|
UTSW |
10 |
28,449,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8049:Ptprk
|
UTSW |
10 |
28,259,565 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8235:Ptprk
|
UTSW |
10 |
28,465,037 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8274:Ptprk
|
UTSW |
10 |
28,456,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8286:Ptprk
|
UTSW |
10 |
28,444,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8372:Ptprk
|
UTSW |
10 |
28,230,688 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8727:Ptprk
|
UTSW |
10 |
28,442,541 (GRCm39) |
unclassified |
probably benign |
|
|
R8794:Ptprk
|
UTSW |
10 |
28,139,504 (GRCm39) |
nonsense |
probably null |
|
|
R8842:Ptprk
|
UTSW |
10 |
28,442,497 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8861:Ptprk
|
UTSW |
10 |
28,446,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8897:Ptprk
|
UTSW |
10 |
28,467,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8910:Ptprk
|
UTSW |
10 |
28,368,993 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8919:Ptprk
|
UTSW |
10 |
28,359,203 (GRCm39) |
nonsense |
probably null |
|
|
R8976:Ptprk
|
UTSW |
10 |
28,461,669 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8982:Ptprk
|
UTSW |
10 |
28,436,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Ptprk
|
UTSW |
10 |
28,461,928 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9135:Ptprk
|
UTSW |
10 |
28,456,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9308:Ptprk
|
UTSW |
10 |
28,450,850 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9317:Ptprk
|
UTSW |
10 |
28,230,731 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9475:Ptprk
|
UTSW |
10 |
28,210,476 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R9585:Ptprk
|
UTSW |
10 |
28,369,147 (GRCm39) |
nonsense |
probably null |
|
|
R9625:Ptprk
|
UTSW |
10 |
28,462,006 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9700:Ptprk
|
UTSW |
10 |
28,456,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9745:Ptprk
|
UTSW |
10 |
28,139,608 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
Z1177:Ptprk
|
UTSW |
10 |
28,369,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGTTTACAGGCCCAGTTCATG -3'
(R):5'- AGCATTTGTGTATACCGGTCTC -3'
Sequencing Primer
(F):5'- GGCCCAGTTCATGAAACCGTATATG -3'
(R):5'- GAAAGCTCACTTAGGAGCAT -3'
|
| Posted On |
2017-05-26 |
Incidental Mutation