Incidental Mutation 'R4824:Anapc1'
| ID |
406161 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
042440-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4824 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 128470610 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 1507
(T1507S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000014499
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
|
| AlphaFold |
P53995 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000014499
AA Change: T1507S
PolyPhen 2
Score 0.690 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: T1507S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145906
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154320
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154995
|
| Meta Mutation Damage Score |
0.1707 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.0%
|
| Validation Efficiency |
98% (123/126) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 107 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,771,437 (GRCm39) |
T209A |
probably benign |
Het |
| 1700086D15Rik |
T |
C |
11: 65,043,441 (GRCm39) |
|
probably benign |
Het |
| A130010J15Rik |
G |
A |
1: 192,856,965 (GRCm39) |
V106I |
probably benign |
Het |
| Abca16 |
C |
A |
7: 120,074,702 (GRCm39) |
N580K |
possibly damaging |
Het |
| Actrt2 |
A |
T |
4: 154,751,344 (GRCm39) |
F264Y |
probably damaging |
Het |
| Adh4 |
G |
A |
3: 138,134,807 (GRCm39) |
S327N |
possibly damaging |
Het |
| Alkbh5 |
T |
C |
11: 60,444,697 (GRCm39) |
|
probably null |
Het |
| Anapc2 |
A |
G |
2: 25,167,764 (GRCm39) |
R444G |
probably damaging |
Het |
| Apoh |
G |
T |
11: 108,305,087 (GRCm39) |
W335L |
probably benign |
Het |
| B4galt7 |
A |
T |
13: 55,752,162 (GRCm39) |
H71L |
possibly damaging |
Het |
| Bicd2 |
A |
G |
13: 49,532,488 (GRCm39) |
E358G |
probably damaging |
Het |
| Bmper |
T |
A |
9: 23,134,956 (GRCm39) |
V7D |
possibly damaging |
Het |
| Brca2 |
T |
C |
5: 150,463,200 (GRCm39) |
F988S |
probably damaging |
Het |
| Brix1 |
A |
G |
15: 10,485,828 (GRCm39) |
V49A |
possibly damaging |
Het |
| Brpf3 |
T |
C |
17: 29,025,460 (GRCm39) |
S178P |
probably benign |
Het |
| Btaf1 |
A |
G |
19: 36,958,448 (GRCm39) |
Y655C |
possibly damaging |
Het |
| C1rl |
C |
G |
6: 124,486,040 (GRCm39) |
Y470* |
probably null |
Het |
| Cacnb4 |
A |
G |
2: 52,565,822 (GRCm39) |
V21A |
probably benign |
Het |
| Caskin1 |
C |
A |
17: 24,720,103 (GRCm39) |
P437T |
probably benign |
Het |
| Casz1 |
C |
A |
4: 149,029,028 (GRCm39) |
P1158T |
probably damaging |
Het |
| Ccdc141 |
T |
A |
2: 76,954,680 (GRCm39) |
Q189L |
probably damaging |
Het |
| Ccr3 |
T |
C |
9: 123,828,809 (GRCm39) |
V48A |
probably damaging |
Het |
| Cebpd |
G |
A |
16: 15,705,978 (GRCm39) |
G264S |
probably benign |
Het |
| Cert1 |
C |
T |
13: 96,752,995 (GRCm39) |
P350S |
probably benign |
Het |
| Cfap20dc |
A |
T |
14: 8,665,997 (GRCm38) |
M1K |
probably null |
Het |
| Chd1 |
C |
A |
17: 15,953,386 (GRCm39) |
S440R |
probably damaging |
Het |
| Clip1 |
T |
A |
5: 123,769,086 (GRCm39) |
E504D |
probably damaging |
Het |
| Cmya5 |
T |
C |
13: 93,230,082 (GRCm39) |
R1669G |
probably benign |
Het |
| Col11a2 |
T |
A |
17: 34,269,937 (GRCm39) |
F456I |
probably damaging |
Het |
| Ctnna2 |
A |
T |
6: 76,957,764 (GRCm39) |
M130K |
probably damaging |
Het |
| Elmo2 |
A |
T |
2: 165,133,922 (GRCm39) |
|
probably benign |
Het |
| F11 |
T |
C |
8: 45,708,379 (GRCm39) |
D27G |
probably damaging |
Het |
| Faap100 |
A |
T |
11: 120,266,412 (GRCm39) |
|
probably null |
Het |
| Fat1 |
A |
G |
8: 45,442,151 (GRCm39) |
E1151G |
probably damaging |
Het |
| Fbll1 |
T |
A |
11: 35,688,652 (GRCm39) |
I204F |
probably damaging |
Het |
| Gle1 |
T |
A |
2: 29,830,215 (GRCm39) |
V257D |
possibly damaging |
Het |
| Hoxc9 |
T |
A |
15: 102,890,225 (GRCm39) |
C47* |
probably null |
Het |
| Hsd17b6 |
A |
G |
10: 127,829,524 (GRCm39) |
V226A |
probably benign |
Het |
| Hsd17b7 |
C |
T |
1: 169,788,764 (GRCm39) |
R151Q |
probably benign |
Het |
| Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
| Ido2 |
A |
G |
8: 25,023,875 (GRCm39) |
I321T |
probably benign |
Het |
| Irf2bp2 |
T |
C |
8: 127,318,172 (GRCm39) |
T465A |
probably benign |
Het |
| Kdm2a |
A |
G |
19: 4,412,815 (GRCm39) |
M34T |
probably damaging |
Het |
| Klhl6 |
C |
T |
16: 19,775,778 (GRCm39) |
R260H |
probably damaging |
Het |
| Kntc1 |
T |
A |
5: 123,928,196 (GRCm39) |
L1231* |
probably null |
Het |
| Lca5l |
A |
C |
16: 95,963,229 (GRCm39) |
Y412* |
probably null |
Het |
| Lipt1 |
T |
C |
1: 37,914,513 (GRCm39) |
S190P |
possibly damaging |
Het |
| Ly6f |
T |
A |
15: 75,143,569 (GRCm39) |
V92D |
probably damaging |
Het |
| Matn4 |
T |
A |
2: 164,235,151 (GRCm39) |
M433L |
probably benign |
Het |
| Mbtd1 |
C |
A |
11: 93,816,528 (GRCm39) |
P370T |
probably benign |
Het |
| Mcph1 |
T |
A |
8: 18,682,703 (GRCm39) |
|
probably null |
Het |
| Muc5b |
T |
A |
7: 141,417,922 (GRCm39) |
C3623S |
probably damaging |
Het |
| Myt1l |
C |
A |
12: 29,899,399 (GRCm39) |
H134N |
probably benign |
Het |
| Nav2 |
A |
T |
7: 49,058,749 (GRCm39) |
|
probably benign |
Het |
| Ndufaf8 |
T |
C |
11: 119,989,992 (GRCm39) |
C35R |
probably damaging |
Het |
| Neb |
G |
A |
2: 52,094,891 (GRCm39) |
T5130I |
possibly damaging |
Het |
| Nlrp9c |
T |
C |
7: 26,079,989 (GRCm39) |
N624S |
possibly damaging |
Het |
| Nr0b2 |
C |
A |
4: 133,283,334 (GRCm39) |
H190Q |
probably damaging |
Het |
| Nrg4 |
A |
G |
9: 55,156,405 (GRCm39) |
|
probably benign |
Het |
| Nup88 |
A |
T |
11: 70,852,450 (GRCm39) |
V215E |
probably benign |
Het |
| Oas2 |
T |
G |
5: 120,876,411 (GRCm39) |
T511P |
probably benign |
Het |
| Or1e25 |
A |
G |
11: 73,493,426 (GRCm39) |
T7A |
possibly damaging |
Het |
| Or2t6 |
A |
G |
14: 14,175,885 (GRCm38) |
S66P |
probably damaging |
Het |
| Or5d14 |
A |
C |
2: 87,880,432 (GRCm39) |
F179V |
probably damaging |
Het |
| Or5w8 |
T |
C |
2: 87,687,621 (GRCm39) |
V34A |
probably benign |
Het |
| Or8g26 |
A |
G |
9: 39,095,501 (GRCm39) |
N9S |
probably benign |
Het |
| Or9q1 |
A |
C |
19: 13,805,718 (GRCm39) |
L14R |
probably damaging |
Het |
| Pcdhgb2 |
T |
A |
18: 37,823,502 (GRCm39) |
N164K |
probably damaging |
Het |
| Pde4d |
C |
G |
13: 109,253,400 (GRCm39) |
P76A |
probably benign |
Het |
| Phlda1 |
T |
C |
10: 111,343,516 (GRCm39) |
|
probably benign |
Het |
| Plekhh1 |
A |
G |
12: 79,101,577 (GRCm39) |
T216A |
probably benign |
Het |
| Plppr3 |
T |
A |
10: 79,701,507 (GRCm39) |
E445V |
possibly damaging |
Het |
| Prom1 |
A |
G |
5: 44,191,732 (GRCm39) |
V337A |
probably damaging |
Het |
| Prr14l |
T |
C |
5: 33,001,743 (GRCm39) |
|
probably benign |
Het |
| Psmd1 |
A |
G |
1: 86,064,820 (GRCm39) |
I951V |
probably benign |
Het |
| Rab35 |
T |
G |
5: 115,781,454 (GRCm39) |
I85M |
possibly damaging |
Het |
| Rad9a |
A |
T |
19: 4,250,536 (GRCm39) |
S93T |
probably benign |
Het |
| Ric1 |
G |
A |
19: 29,563,242 (GRCm39) |
C555Y |
probably damaging |
Het |
| Rnd2 |
C |
T |
11: 101,359,825 (GRCm39) |
L57F |
probably damaging |
Het |
| Ror2 |
T |
A |
13: 53,264,719 (GRCm39) |
Q791L |
probably benign |
Het |
| Rps8 |
G |
C |
4: 117,012,352 (GRCm39) |
|
probably benign |
Het |
| Sdr16c5 |
C |
T |
4: 4,016,216 (GRCm39) |
W70* |
probably null |
Het |
| Senp3 |
A |
G |
11: 69,568,821 (GRCm39) |
V408A |
probably benign |
Het |
| Sh2d4b |
C |
A |
14: 40,562,301 (GRCm39) |
W288L |
probably benign |
Het |
| Slc38a9 |
A |
T |
13: 112,859,832 (GRCm39) |
D422V |
probably damaging |
Het |
| Slc4a2 |
T |
C |
5: 24,645,141 (GRCm39) |
F1104L |
probably damaging |
Het |
| Slc4a3 |
A |
G |
1: 75,527,267 (GRCm39) |
K113E |
possibly damaging |
Het |
| Spata3 |
G |
A |
1: 85,952,048 (GRCm39) |
|
probably null |
Het |
| Spata31d1d |
A |
T |
13: 59,877,055 (GRCm39) |
V160E |
possibly damaging |
Het |
| Sprr2f |
A |
G |
3: 92,273,203 (GRCm39) |
M1V |
probably null |
Het |
| Sptbn1 |
A |
G |
11: 30,068,295 (GRCm39) |
V1733A |
possibly damaging |
Het |
| Syce1 |
C |
A |
7: 140,359,809 (GRCm39) |
L83F |
probably damaging |
Het |
| Tardbp |
A |
G |
4: 148,702,050 (GRCm39) |
I295T |
probably benign |
Het |
| Tmem212 |
A |
G |
3: 27,939,157 (GRCm39) |
S110P |
probably damaging |
Het |
| Tnc |
G |
A |
4: 63,935,857 (GRCm39) |
Q360* |
probably null |
Het |
| Tnrc6c |
C |
A |
11: 117,613,731 (GRCm39) |
Q630K |
probably damaging |
Het |
| Ttc19 |
G |
A |
11: 62,199,922 (GRCm39) |
R235H |
probably benign |
Het |
| Ube3b |
T |
A |
5: 114,553,787 (GRCm39) |
|
probably null |
Het |
| Vmn2r31 |
C |
T |
7: 7,390,062 (GRCm39) |
|
probably null |
Het |
| Vmn2r92 |
T |
A |
17: 18,372,183 (GRCm39) |
|
probably benign |
Het |
| Washc5 |
A |
T |
15: 59,205,485 (GRCm39) |
Y685* |
probably null |
Het |
| Wdr93 |
T |
A |
7: 79,399,817 (GRCm39) |
Y135* |
probably null |
Het |
| Wdr95 |
T |
A |
5: 149,518,797 (GRCm39) |
I546K |
probably damaging |
Het |
| Zbtb38 |
T |
A |
9: 96,570,254 (GRCm39) |
T277S |
probably benign |
Het |
| Zfp13 |
T |
C |
17: 23,795,797 (GRCm39) |
D258G |
possibly damaging |
Het |
| Zfp397 |
T |
A |
18: 24,093,249 (GRCm39) |
S245T |
probably benign |
Het |
| Zfp646 |
T |
C |
7: 127,482,907 (GRCm39) |
Y1695H |
probably benign |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACATATATAGCTCTCCCTCATGAAC -3'
(R):5'- GCAAGATCATGCTGTATAAGGC -3'
Sequencing Primer
(F):5'- TTCCTCCTCCCAAAAAGAGAAGG -3'
(R):5'- CTTCCAAGTTCAGATATTTTTG -3'
|
| Posted On |
2016-08-01 |
Incidental Mutation