Incidental Mutation 'R5001:Wdr64'
| ID |
389879 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Wdr64
|
| Ensembl Gene |
ENSMUSG00000026523 |
| Gene Name |
WD repeat domain 64 |
| Synonyms |
4930415O10Rik, 4930511H01Rik |
| MMRRC Submission |
042595-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.060)
|
| Stock # |
R5001 (G1)
|
| Quality Score |
210 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
175526159-175643300 bp(+) (GRCm39) |
| Type of Mutation |
critical splice acceptor site |
| DNA Base Change (assembly) |
A to G
at 175620525 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141740
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094288]
[ENSMUST00000094288]
[ENSMUST00000171939]
[ENSMUST00000171939]
[ENSMUST00000194087]
[ENSMUST00000194087]
[ENSMUST00000194783]
|
| AlphaFold |
Q9D565 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000094288
|
| SMART Domains |
Protein: ENSMUSP00000091846
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
118 |
159 |
2.65e1 |
SMART |
|
WD40
|
162 |
200 |
2.13e1 |
SMART |
|
low complexity region
|
259 |
271 |
N/A |
INTRINSIC |
|
Blast:WD40
|
277 |
316 |
5e-19 |
BLAST |
|
WD40
|
323 |
361 |
2.4e-1 |
SMART |
|
WD40
|
365 |
404 |
8.29e-1 |
SMART |
|
WD40
|
407 |
449 |
1.7e2 |
SMART |
|
WD40
|
457 |
493 |
1.19e1 |
SMART |
|
WD40
|
497 |
538 |
4.55e-3 |
SMART |
|
WD40
|
643 |
684 |
3.31e0 |
SMART |
|
WD40
|
742 |
806 |
7.4e0 |
SMART |
|
Blast:WD40
|
811 |
851 |
7e-17 |
BLAST |
|
WD40
|
864 |
903 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
921 |
964 |
9e-19 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000094288
|
| SMART Domains |
Protein: ENSMUSP00000091846
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
118 |
159 |
2.65e1 |
SMART |
|
WD40
|
162 |
200 |
2.13e1 |
SMART |
|
low complexity region
|
259 |
271 |
N/A |
INTRINSIC |
|
Blast:WD40
|
277 |
316 |
5e-19 |
BLAST |
|
WD40
|
323 |
361 |
2.4e-1 |
SMART |
|
WD40
|
365 |
404 |
8.29e-1 |
SMART |
|
WD40
|
407 |
449 |
1.7e2 |
SMART |
|
WD40
|
457 |
493 |
1.19e1 |
SMART |
|
WD40
|
497 |
538 |
4.55e-3 |
SMART |
|
WD40
|
643 |
684 |
3.31e0 |
SMART |
|
WD40
|
742 |
806 |
7.4e0 |
SMART |
|
Blast:WD40
|
811 |
851 |
7e-17 |
BLAST |
|
WD40
|
864 |
903 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
921 |
964 |
9e-19 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000171939
|
| SMART Domains |
Protein: ENSMUSP00000128678
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
5.73e0 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
306 |
4e-19 |
BLAST |
|
WD40
|
313 |
351 |
2.4e-1 |
SMART |
|
WD40
|
355 |
394 |
8.29e-1 |
SMART |
|
WD40
|
397 |
439 |
1.7e2 |
SMART |
|
WD40
|
447 |
483 |
1.19e1 |
SMART |
|
WD40
|
487 |
528 |
4.55e-3 |
SMART |
|
WD40
|
633 |
674 |
3.31e0 |
SMART |
|
WD40
|
732 |
796 |
7.4e0 |
SMART |
|
Blast:WD40
|
801 |
841 |
5e-17 |
BLAST |
|
WD40
|
854 |
893 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000171939
|
| SMART Domains |
Protein: ENSMUSP00000128678
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
5.73e0 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
306 |
4e-19 |
BLAST |
|
WD40
|
313 |
351 |
2.4e-1 |
SMART |
|
WD40
|
355 |
394 |
8.29e-1 |
SMART |
|
WD40
|
397 |
439 |
1.7e2 |
SMART |
|
WD40
|
447 |
483 |
1.19e1 |
SMART |
|
WD40
|
487 |
528 |
4.55e-3 |
SMART |
|
WD40
|
633 |
674 |
3.31e0 |
SMART |
|
WD40
|
732 |
796 |
7.4e0 |
SMART |
|
Blast:WD40
|
801 |
841 |
5e-17 |
BLAST |
|
WD40
|
854 |
893 |
4.62e-4 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000194087
|
| SMART Domains |
Protein: ENSMUSP00000141740
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
3.6e-2 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
305 |
5e-19 |
BLAST |
|
WD40
|
313 |
351 |
1.5e-3 |
SMART |
|
WD40
|
355 |
394 |
5.2e-3 |
SMART |
|
WD40
|
397 |
439 |
1.1e0 |
SMART |
|
WD40
|
447 |
483 |
7.6e-2 |
SMART |
|
WD40
|
487 |
528 |
2.9e-5 |
SMART |
|
WD40
|
633 |
674 |
2.1e-2 |
SMART |
|
WD40
|
732 |
796 |
4.7e-2 |
SMART |
|
Blast:WD40
|
801 |
841 |
6e-17 |
BLAST |
|
WD40
|
854 |
893 |
2.9e-6 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000194087
|
| SMART Domains |
Protein: ENSMUSP00000141740
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
151 |
190 |
3.6e-2 |
SMART |
|
low complexity region
|
249 |
261 |
N/A |
INTRINSIC |
|
Blast:WD40
|
267 |
305 |
5e-19 |
BLAST |
|
WD40
|
313 |
351 |
1.5e-3 |
SMART |
|
WD40
|
355 |
394 |
5.2e-3 |
SMART |
|
WD40
|
397 |
439 |
1.1e0 |
SMART |
|
WD40
|
447 |
483 |
7.6e-2 |
SMART |
|
WD40
|
487 |
528 |
2.9e-5 |
SMART |
|
WD40
|
633 |
674 |
2.1e-2 |
SMART |
|
WD40
|
732 |
796 |
4.7e-2 |
SMART |
|
Blast:WD40
|
801 |
841 |
6e-17 |
BLAST |
|
WD40
|
854 |
893 |
2.9e-6 |
SMART |
|
Blast:XPGN
|
911 |
954 |
1e-18 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194783
|
| SMART Domains |
Protein: ENSMUSP00000141384
Gene: ENSMUSG00000026523
| Domain | Start | End | E-Value | Type |
|---|
|
WD40
|
6 |
42 |
7.6e-2 |
SMART |
|
WD40
|
46 |
87 |
2.9e-5 |
SMART |
|
WD40
|
192 |
233 |
2.1e-2 |
SMART |
|
WD40
|
291 |
355 |
4.7e-2 |
SMART |
|
Blast:WD40
|
360 |
400 |
4e-17 |
BLAST |
|
WD40
|
413 |
452 |
2.9e-6 |
SMART |
|
Blast:XPGN
|
470 |
519 |
3e-19 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(1) : Gene trapped(1)
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy3 |
G |
A |
12: 4,248,434 (GRCm39) |
V499M |
possibly damaging |
Het |
| Aff4 |
T |
C |
11: 53,295,184 (GRCm39) |
S795P |
probably damaging |
Het |
| Ank |
G |
A |
15: 27,562,819 (GRCm39) |
V176I |
probably damaging |
Het |
| Ankfn1 |
A |
G |
11: 89,332,268 (GRCm39) |
I446T |
possibly damaging |
Het |
| Arhgap33 |
C |
A |
7: 30,232,441 (GRCm39) |
S32I |
possibly damaging |
Het |
| Ascc3 |
T |
A |
10: 50,699,744 (GRCm39) |
Y1856N |
probably damaging |
Het |
| Atf3 |
T |
C |
1: 190,909,472 (GRCm39) |
T66A |
probably benign |
Het |
| Atf7ip |
T |
C |
6: 136,538,386 (GRCm39) |
C548R |
probably damaging |
Het |
| Bag6 |
A |
G |
17: 35,364,152 (GRCm39) |
T841A |
probably damaging |
Het |
| Bbof1 |
A |
T |
12: 84,473,630 (GRCm39) |
Q320L |
possibly damaging |
Het |
| Bmp2k |
A |
T |
5: 97,201,001 (GRCm39) |
Q307L |
probably damaging |
Het |
| Btaf1 |
T |
A |
19: 36,964,052 (GRCm39) |
N874K |
possibly damaging |
Het |
| Calr4 |
G |
A |
4: 109,096,179 (GRCm39) |
|
probably null |
Het |
| Camk1d |
T |
C |
2: 5,317,912 (GRCm39) |
I248V |
possibly damaging |
Het |
| Ccdc177 |
G |
A |
12: 80,804,160 (GRCm39) |
R705C |
unknown |
Het |
| Cdk18 |
C |
T |
1: 132,046,587 (GRCm39) |
|
probably null |
Het |
| Cers4 |
A |
G |
8: 4,565,565 (GRCm39) |
S4G |
probably benign |
Het |
| Cfap54 |
A |
G |
10: 92,800,396 (GRCm39) |
V1604A |
probably benign |
Het |
| Chd8 |
C |
T |
14: 52,441,372 (GRCm39) |
G907S |
probably benign |
Het |
| Cilk1 |
T |
C |
9: 78,038,801 (GRCm39) |
S17P |
probably damaging |
Het |
| Cnksr3 |
G |
A |
10: 7,076,746 (GRCm39) |
Q149* |
probably null |
Het |
| Cntd1 |
T |
C |
11: 101,176,557 (GRCm39) |
V218A |
possibly damaging |
Het |
| Cog7 |
A |
T |
7: 121,549,109 (GRCm39) |
V384E |
probably damaging |
Het |
| Col5a2 |
A |
G |
1: 45,542,058 (GRCm39) |
V6A |
unknown |
Het |
| Col7a1 |
T |
C |
9: 108,794,146 (GRCm39) |
|
probably null |
Het |
| Cpsf6 |
T |
A |
10: 117,203,866 (GRCm39) |
I29L |
possibly damaging |
Het |
| Cyp3a13 |
T |
C |
5: 137,897,178 (GRCm39) |
T379A |
probably benign |
Het |
| Ddx46 |
T |
C |
13: 55,800,732 (GRCm39) |
S296P |
probably damaging |
Het |
| Dmbt1 |
A |
G |
7: 130,651,742 (GRCm39) |
D328G |
probably damaging |
Het |
| Dnah8 |
T |
G |
17: 31,006,159 (GRCm39) |
L3692W |
probably damaging |
Het |
| Dnmt3l |
A |
C |
10: 77,895,565 (GRCm39) |
S368R |
probably null |
Het |
| Egfr |
A |
G |
11: 16,854,434 (GRCm39) |
K869E |
probably damaging |
Het |
| Ehd1 |
G |
A |
19: 6,347,724 (GRCm39) |
M359I |
probably benign |
Het |
| F5 |
A |
T |
1: 164,023,139 (GRCm39) |
T1566S |
probably benign |
Het |
| Flrt2 |
T |
C |
12: 95,745,725 (GRCm39) |
I21T |
probably benign |
Het |
| Galnt1 |
T |
A |
18: 24,404,812 (GRCm39) |
I383K |
probably benign |
Het |
| Ghdc |
G |
T |
11: 100,657,660 (GRCm39) |
A523D |
probably damaging |
Het |
| Gm24022 |
A |
G |
12: 113,393,399 (GRCm39) |
|
probably benign |
Het |
| Golga3 |
T |
C |
5: 110,353,643 (GRCm39) |
S934P |
probably damaging |
Het |
| Gpr135 |
T |
A |
12: 72,117,282 (GRCm39) |
T162S |
probably benign |
Het |
| Gucd1 |
G |
A |
10: 75,353,036 (GRCm39) |
|
probably null |
Het |
| Hcrtr2 |
T |
A |
9: 76,137,886 (GRCm39) |
I410F |
probably benign |
Het |
| Igkv6-15 |
T |
C |
6: 70,383,633 (GRCm39) |
Y56C |
probably damaging |
Het |
| Il22ra1 |
A |
T |
4: 135,460,415 (GRCm39) |
Y57F |
probably damaging |
Het |
| Irak4 |
A |
G |
15: 94,456,154 (GRCm39) |
E247G |
possibly damaging |
Het |
| Kank3 |
T |
C |
17: 34,040,746 (GRCm39) |
V13A |
possibly damaging |
Het |
| Klhl1 |
A |
T |
14: 96,374,046 (GRCm39) |
S667T |
probably damaging |
Het |
| Klhl6 |
T |
G |
16: 19,765,741 (GRCm39) |
*620C |
probably null |
Het |
| Lct |
A |
G |
1: 128,235,978 (GRCm39) |
L343P |
probably damaging |
Het |
| Lgr6 |
G |
T |
1: 134,918,370 (GRCm39) |
P264T |
probably benign |
Het |
| Lilrb4a |
T |
A |
10: 51,367,516 (GRCm39) |
|
probably null |
Het |
| Lin7a |
G |
T |
10: 107,218,530 (GRCm39) |
G25* |
probably null |
Het |
| Lmnb2 |
G |
A |
10: 80,753,946 (GRCm39) |
T36M |
probably damaging |
Het |
| Manba |
T |
C |
3: 135,273,391 (GRCm39) |
F775S |
probably benign |
Het |
| Marchf6 |
A |
G |
15: 31,465,468 (GRCm39) |
V812A |
probably damaging |
Het |
| Megf6 |
T |
A |
4: 154,352,517 (GRCm39) |
L1292H |
probably damaging |
Het |
| Myo18b |
T |
G |
5: 112,909,206 (GRCm39) |
Q1979P |
probably damaging |
Het |
| Myoz1 |
T |
C |
14: 20,703,769 (GRCm39) |
M59V |
probably damaging |
Het |
| Naa35 |
T |
C |
13: 59,773,345 (GRCm39) |
I100T |
possibly damaging |
Het |
| Nox4 |
A |
T |
7: 87,010,011 (GRCm39) |
Y404F |
probably damaging |
Het |
| Ntn1 |
T |
C |
11: 68,151,358 (GRCm39) |
Y441C |
probably damaging |
Het |
| Onecut3 |
A |
G |
10: 80,331,154 (GRCm39) |
T105A |
unknown |
Het |
| Or10ak8 |
C |
A |
4: 118,774,440 (GRCm39) |
V75F |
probably damaging |
Het |
| Or1n1 |
T |
C |
2: 36,750,082 (GRCm39) |
T93A |
probably benign |
Het |
| Or4d5 |
G |
A |
9: 40,012,523 (GRCm39) |
H88Y |
probably benign |
Het |
| Pabpc1l |
A |
G |
2: 163,884,438 (GRCm39) |
S392G |
probably benign |
Het |
| Pan3 |
T |
A |
5: 147,463,492 (GRCm39) |
|
probably null |
Het |
| Pcdha4 |
G |
A |
18: 37,088,001 (GRCm39) |
S728N |
probably benign |
Het |
| Pds5a |
T |
C |
5: 65,854,128 (GRCm39) |
D38G |
probably damaging |
Het |
| Pgm2l1 |
A |
G |
7: 99,921,583 (GRCm39) |
I605V |
probably benign |
Het |
| Phip |
T |
C |
9: 82,778,072 (GRCm39) |
|
probably null |
Het |
| Pilra |
T |
C |
5: 137,833,777 (GRCm39) |
I96M |
probably damaging |
Het |
| Ppig |
T |
A |
2: 69,571,830 (GRCm39) |
V183D |
unknown |
Het |
| Ppp2r2a |
A |
T |
14: 67,259,757 (GRCm39) |
L313* |
probably null |
Het |
| Ppp4c |
A |
G |
7: 126,386,709 (GRCm39) |
F126S |
probably damaging |
Het |
| Ptger2 |
C |
A |
14: 45,226,824 (GRCm39) |
R135S |
probably damaging |
Het |
| Rab11fip5 |
T |
A |
6: 85,324,788 (GRCm39) |
E506D |
probably damaging |
Het |
| Rdh12 |
G |
A |
12: 79,259,516 (GRCm39) |
G133R |
probably damaging |
Het |
| Rims2 |
A |
T |
15: 39,315,824 (GRCm39) |
D610V |
probably benign |
Het |
| Saa1 |
T |
A |
7: 46,390,132 (GRCm39) |
Y122F |
probably damaging |
Het |
| Septin10 |
A |
T |
10: 59,012,811 (GRCm39) |
V269E |
probably damaging |
Het |
| Serpina3n |
T |
A |
12: 104,374,998 (GRCm39) |
D23E |
probably benign |
Het |
| Serpinb11 |
A |
G |
1: 107,304,598 (GRCm39) |
K188E |
possibly damaging |
Het |
| Slc18a3 |
C |
T |
14: 32,185,736 (GRCm39) |
V216M |
possibly damaging |
Het |
| Slc19a3 |
G |
T |
1: 83,000,341 (GRCm39) |
N225K |
probably benign |
Het |
| Slc4a1 |
T |
A |
11: 102,242,329 (GRCm39) |
I797F |
probably benign |
Het |
| Slx9 |
A |
G |
10: 77,325,850 (GRCm39) |
V154A |
probably benign |
Het |
| Spic |
A |
G |
10: 88,511,761 (GRCm39) |
M165T |
possibly damaging |
Het |
| Timm44 |
A |
T |
8: 4,325,886 (GRCm39) |
M1K |
probably null |
Het |
| Tmc6 |
A |
G |
11: 117,661,610 (GRCm39) |
L572P |
probably benign |
Het |
| Tnc |
G |
A |
4: 63,918,299 (GRCm39) |
T1204M |
probably benign |
Het |
| Tnc |
G |
A |
4: 63,902,726 (GRCm39) |
T1517I |
probably damaging |
Het |
| Trip11 |
A |
T |
12: 101,851,169 (GRCm39) |
L680* |
probably null |
Het |
| Trps1 |
T |
A |
15: 50,524,703 (GRCm39) |
M887L |
possibly damaging |
Het |
| Tulp3 |
A |
C |
6: 128,302,031 (GRCm39) |
V330G |
probably damaging |
Het |
| Upf1 |
A |
G |
8: 70,787,350 (GRCm39) |
S835P |
probably damaging |
Het |
| Yju2b |
G |
A |
8: 84,985,304 (GRCm39) |
P322S |
probably benign |
Het |
| Zbtb40 |
A |
G |
4: 136,723,461 (GRCm39) |
L643P |
probably damaging |
Het |
| Zc3h18 |
A |
T |
8: 123,110,259 (GRCm39) |
D36V |
probably damaging |
Het |
|
| Other mutations in Wdr64 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00563:Wdr64
|
APN |
1 |
175,526,366 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00902:Wdr64
|
APN |
1 |
175,556,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01347:Wdr64
|
APN |
1 |
175,547,899 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL01353:Wdr64
|
APN |
1 |
175,559,151 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01583:Wdr64
|
APN |
1 |
175,594,722 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01643:Wdr64
|
APN |
1 |
175,599,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01673:Wdr64
|
APN |
1 |
175,627,922 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
IGL01992:Wdr64
|
APN |
1 |
175,533,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02613:Wdr64
|
APN |
1 |
175,594,613 (GRCm39) |
nonsense |
probably null |
|
|
IGL02834:Wdr64
|
APN |
1 |
175,633,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL03214:Wdr64
|
APN |
1 |
175,571,201 (GRCm39) |
splice site |
probably benign |
|
|
IGL03305:Wdr64
|
APN |
1 |
175,583,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03308:Wdr64
|
APN |
1 |
175,594,562 (GRCm39) |
unclassified |
probably benign |
|
|
PIT4418001:Wdr64
|
UTSW |
1 |
175,571,160 (GRCm39) |
nonsense |
probably null |
|
|
R0036:Wdr64
|
UTSW |
1 |
175,556,496 (GRCm39) |
nonsense |
probably null |
|
|
R0041:Wdr64
|
UTSW |
1 |
175,554,037 (GRCm39) |
nonsense |
probably null |
|
|
R0041:Wdr64
|
UTSW |
1 |
175,554,037 (GRCm39) |
nonsense |
probably null |
|
|
R0079:Wdr64
|
UTSW |
1 |
175,622,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0380:Wdr64
|
UTSW |
1 |
175,597,208 (GRCm39) |
splice site |
probably benign |
|
|
R0486:Wdr64
|
UTSW |
1 |
175,622,769 (GRCm39) |
splice site |
probably benign |
|
|
R0520:Wdr64
|
UTSW |
1 |
175,553,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0598:Wdr64
|
UTSW |
1 |
175,633,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0711:Wdr64
|
UTSW |
1 |
175,599,751 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0746:Wdr64
|
UTSW |
1 |
175,620,539 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0927:Wdr64
|
UTSW |
1 |
175,620,647 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0947:Wdr64
|
UTSW |
1 |
175,603,315 (GRCm39) |
missense |
probably benign |
|
|
R1014:Wdr64
|
UTSW |
1 |
175,583,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1332:Wdr64
|
UTSW |
1 |
175,622,706 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1416:Wdr64
|
UTSW |
1 |
175,633,568 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1421:Wdr64
|
UTSW |
1 |
175,594,716 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1467:Wdr64
|
UTSW |
1 |
175,603,288 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1467:Wdr64
|
UTSW |
1 |
175,603,288 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1796:Wdr64
|
UTSW |
1 |
175,544,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1797:Wdr64
|
UTSW |
1 |
175,639,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2145:Wdr64
|
UTSW |
1 |
175,594,661 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2321:Wdr64
|
UTSW |
1 |
175,622,653 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R2449:Wdr64
|
UTSW |
1 |
175,526,479 (GRCm39) |
missense |
probably benign |
|
|
R4049:Wdr64
|
UTSW |
1 |
175,633,422 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4155:Wdr64
|
UTSW |
1 |
175,597,172 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4624:Wdr64
|
UTSW |
1 |
175,599,829 (GRCm39) |
missense |
probably benign |
|
|
R4661:Wdr64
|
UTSW |
1 |
175,554,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4711:Wdr64
|
UTSW |
1 |
175,626,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4891:Wdr64
|
UTSW |
1 |
175,526,345 (GRCm39) |
unclassified |
probably benign |
|
|
R4925:Wdr64
|
UTSW |
1 |
175,552,268 (GRCm39) |
splice site |
probably null |
|
|
R4943:Wdr64
|
UTSW |
1 |
175,547,882 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5000:Wdr64
|
UTSW |
1 |
175,553,941 (GRCm39) |
splice site |
probably null |
|
|
R5143:Wdr64
|
UTSW |
1 |
175,553,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Wdr64
|
UTSW |
1 |
175,583,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5813:Wdr64
|
UTSW |
1 |
175,639,623 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6014:Wdr64
|
UTSW |
1 |
175,633,556 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6417:Wdr64
|
UTSW |
1 |
175,553,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6456:Wdr64
|
UTSW |
1 |
175,613,175 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6555:Wdr64
|
UTSW |
1 |
175,547,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6576:Wdr64
|
UTSW |
1 |
175,633,494 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6797:Wdr64
|
UTSW |
1 |
175,638,176 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6891:Wdr64
|
UTSW |
1 |
175,533,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Wdr64
|
UTSW |
1 |
175,533,555 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7205:Wdr64
|
UTSW |
1 |
175,617,499 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7252:Wdr64
|
UTSW |
1 |
175,603,240 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7552:Wdr64
|
UTSW |
1 |
175,613,147 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7732:Wdr64
|
UTSW |
1 |
175,617,495 (GRCm39) |
missense |
probably benign |
|
|
R7777:Wdr64
|
UTSW |
1 |
175,617,564 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7780:Wdr64
|
UTSW |
1 |
175,556,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7810:Wdr64
|
UTSW |
1 |
175,559,092 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7833:Wdr64
|
UTSW |
1 |
175,591,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7843:Wdr64
|
UTSW |
1 |
175,639,668 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7887:Wdr64
|
UTSW |
1 |
175,613,111 (GRCm39) |
missense |
not run |
|
|
R7991:Wdr64
|
UTSW |
1 |
175,554,051 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8124:Wdr64
|
UTSW |
1 |
175,626,844 (GRCm39) |
splice site |
probably null |
|
|
R8129:Wdr64
|
UTSW |
1 |
175,603,154 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8673:Wdr64
|
UTSW |
1 |
175,633,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8728:Wdr64
|
UTSW |
1 |
175,559,079 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8786:Wdr64
|
UTSW |
1 |
175,636,327 (GRCm39) |
nonsense |
probably null |
|
|
R8822:Wdr64
|
UTSW |
1 |
175,544,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8842:Wdr64
|
UTSW |
1 |
175,599,893 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8887:Wdr64
|
UTSW |
1 |
175,599,850 (GRCm39) |
missense |
probably benign |
0.17 |
|
R9014:Wdr64
|
UTSW |
1 |
175,526,395 (GRCm39) |
missense |
probably benign |
|
|
R9330:Wdr64
|
UTSW |
1 |
175,554,024 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9332:Wdr64
|
UTSW |
1 |
175,599,871 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9465:Wdr64
|
UTSW |
1 |
175,618,823 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9716:Wdr64
|
UTSW |
1 |
175,622,658 (GRCm39) |
missense |
probably benign |
|
|
R9717:Wdr64
|
UTSW |
1 |
175,544,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Wdr64
|
UTSW |
1 |
175,533,551 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTTACAAATAGGACCCCGGC -3'
(R):5'- TTTTGAGTCCCAGTCAACACC -3'
Sequencing Primer
(F):5'- AGACTTTCCCAGTGATCCAGG -3'
(R):5'- CAAACTTCATCACCTCCAGCGTC -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation