Incidental Mutation 'R4965:Zfp106'
| ID |
383871 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4965 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 120364400 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 669
(D669V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000135625]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055241
AA Change: D692V
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: D692V
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135625
|
| SMART Domains |
Protein: ENSMUSP00000126939
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
low complexity region
|
53 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141874
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147353
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163384
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167241
|
| SMART Domains |
Protein: ENSMUSP00000127803
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
28 |
1.51e0 |
SMART |
|
low complexity region
|
74 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
145 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171215
AA Change: D669V
PolyPhen 2
Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: D669V
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000181963
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.7%
- 20x: 90.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 117 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,775,433 (GRCm39) |
T1541A |
probably benign |
Het |
| 9530002B09Rik |
T |
C |
4: 122,594,285 (GRCm39) |
M59T |
probably benign |
Het |
| Adam18 |
C |
T |
8: 25,131,827 (GRCm39) |
C428Y |
probably damaging |
Het |
| Adcy5 |
A |
G |
16: 35,098,872 (GRCm39) |
E700G |
possibly damaging |
Het |
| Adprh |
G |
T |
16: 38,266,142 (GRCm39) |
Y333* |
probably null |
Het |
| Agfg2 |
C |
A |
5: 137,665,439 (GRCm39) |
|
probably null |
Het |
| Akip1 |
A |
T |
7: 109,310,961 (GRCm39) |
E167V |
probably damaging |
Het |
| Akr1c21 |
A |
T |
13: 4,630,304 (GRCm39) |
Q199L |
probably damaging |
Het |
| Aldh9a1 |
C |
A |
1: 167,193,358 (GRCm39) |
A455E |
probably damaging |
Het |
| Amph |
G |
A |
13: 19,321,869 (GRCm39) |
S520N |
probably benign |
Het |
| Ankrd52 |
A |
G |
10: 128,226,376 (GRCm39) |
D1006G |
probably benign |
Het |
| Ap5z1 |
A |
C |
5: 142,453,431 (GRCm39) |
Q133P |
probably damaging |
Het |
| Babam1 |
C |
T |
8: 71,857,032 (GRCm39) |
A331V |
possibly damaging |
Het |
| Btc |
T |
C |
5: 91,510,160 (GRCm39) |
|
probably null |
Het |
| Cacna2d3 |
A |
G |
14: 28,704,289 (GRCm39) |
F831L |
probably benign |
Het |
| Cadm3 |
G |
A |
1: 173,164,664 (GRCm39) |
P372L |
probably damaging |
Het |
| Capn5 |
A |
T |
7: 97,775,624 (GRCm39) |
M439K |
probably damaging |
Het |
| Carf |
T |
C |
1: 60,189,796 (GRCm39) |
S639P |
probably damaging |
Het |
| Casp12 |
C |
T |
9: 5,352,250 (GRCm39) |
R81C |
probably benign |
Het |
| Ces2e |
G |
T |
8: 105,660,330 (GRCm39) |
R555M |
probably benign |
Het |
| Cfap54 |
T |
A |
10: 92,902,661 (GRCm39) |
I164F |
probably benign |
Het |
| Cltc |
C |
T |
11: 86,598,327 (GRCm39) |
V1012I |
probably damaging |
Het |
| Cmya5 |
G |
A |
13: 93,232,295 (GRCm39) |
T931I |
possibly damaging |
Het |
| Cntn6 |
A |
G |
6: 104,751,435 (GRCm39) |
I364V |
probably damaging |
Het |
| Cntnap1 |
A |
T |
11: 101,068,251 (GRCm39) |
I59F |
possibly damaging |
Het |
| Cop1 |
T |
C |
1: 159,067,167 (GRCm39) |
M80T |
probably damaging |
Het |
| Cplx2 |
A |
G |
13: 54,527,460 (GRCm39) |
S115G |
possibly damaging |
Het |
| Crtac1 |
A |
G |
19: 42,307,179 (GRCm39) |
Y195H |
probably damaging |
Het |
| Csn1s2a |
A |
C |
5: 87,929,697 (GRCm39) |
S99R |
possibly damaging |
Het |
| Csn1s2b |
T |
A |
5: 87,961,820 (GRCm39) |
D41E |
possibly damaging |
Het |
| Cul9 |
C |
T |
17: 46,849,451 (GRCm39) |
D565N |
probably damaging |
Het |
| Cux1 |
A |
T |
5: 136,340,410 (GRCm39) |
N625K |
possibly damaging |
Het |
| Cyp2c37 |
A |
T |
19: 40,000,206 (GRCm39) |
M443L |
possibly damaging |
Het |
| Cyp2s1 |
G |
A |
7: 25,508,710 (GRCm39) |
T244I |
possibly damaging |
Het |
| Dgkh |
C |
T |
14: 78,861,861 (GRCm39) |
V135M |
probably damaging |
Het |
| Dtl |
T |
C |
1: 191,278,677 (GRCm39) |
E395G |
possibly damaging |
Het |
| Dyrk1a |
G |
T |
16: 94,492,854 (GRCm39) |
G658* |
probably null |
Het |
| Erlin2 |
T |
C |
8: 27,519,623 (GRCm39) |
F117S |
probably damaging |
Het |
| Fkbp8 |
A |
G |
8: 70,984,173 (GRCm39) |
|
probably null |
Het |
| Fras1 |
T |
C |
5: 96,874,439 (GRCm39) |
F2288S |
possibly damaging |
Het |
| Frmd3 |
A |
G |
4: 74,071,837 (GRCm39) |
T240A |
probably damaging |
Het |
| H2-D1 |
A |
G |
17: 35,482,881 (GRCm39) |
Y137C |
probably damaging |
Het |
| Helz2 |
A |
G |
2: 180,882,709 (GRCm39) |
V28A |
possibly damaging |
Het |
| Hydin |
A |
G |
8: 111,124,727 (GRCm39) |
I579V |
probably benign |
Het |
| Il6 |
A |
T |
5: 30,218,491 (GRCm39) |
Y29F |
possibly damaging |
Het |
| Ildr2 |
A |
G |
1: 166,135,409 (GRCm39) |
D368G |
probably damaging |
Het |
| Junb |
T |
A |
8: 85,704,788 (GRCm39) |
I91F |
probably damaging |
Het |
| Kat2a |
C |
A |
11: 100,603,029 (GRCm39) |
|
probably benign |
Het |
| Kat2a |
A |
T |
11: 100,603,030 (GRCm39) |
|
probably benign |
Het |
| Kcnh5 |
T |
A |
12: 75,011,925 (GRCm39) |
T665S |
probably benign |
Het |
| Kdm1b |
A |
T |
13: 47,227,843 (GRCm39) |
D608V |
probably damaging |
Het |
| Krcc1 |
A |
G |
6: 71,261,621 (GRCm39) |
K218E |
probably damaging |
Het |
| Krt8 |
C |
T |
15: 101,905,386 (GRCm39) |
V488M |
probably benign |
Het |
| Lzts1 |
C |
T |
8: 69,591,414 (GRCm39) |
A245T |
probably benign |
Het |
| Mcm6 |
T |
A |
1: 128,287,223 (GRCm39) |
Q27L |
probably damaging |
Het |
| Mfsd4b3-ps |
G |
T |
10: 39,823,686 (GRCm39) |
Y191* |
probably null |
Het |
| Mgme1 |
C |
T |
2: 144,118,324 (GRCm39) |
Q199* |
probably null |
Het |
| Mgme1 |
T |
C |
2: 144,121,540 (GRCm39) |
L332P |
probably benign |
Het |
| Morc3 |
G |
T |
16: 93,657,475 (GRCm39) |
E25* |
probably null |
Het |
| Mroh7 |
G |
A |
4: 106,548,184 (GRCm39) |
A1098V |
possibly damaging |
Het |
| Mtrf1 |
G |
A |
14: 79,644,027 (GRCm39) |
R174H |
probably benign |
Het |
| Mybpc3 |
G |
A |
2: 90,949,592 (GRCm39) |
G45D |
possibly damaging |
Het |
| Mycbpap |
A |
T |
11: 94,395,764 (GRCm39) |
N733K |
probably damaging |
Het |
| N4bp1 |
T |
C |
8: 87,578,314 (GRCm39) |
I684V |
possibly damaging |
Het |
| Nav2 |
A |
T |
7: 49,202,625 (GRCm39) |
R1470* |
probably null |
Het |
| Ndufa9 |
A |
T |
6: 126,799,026 (GRCm39) |
S364T |
probably benign |
Het |
| Nipal4 |
C |
A |
11: 46,052,837 (GRCm39) |
A43S |
possibly damaging |
Het |
| Nlrp1a |
T |
A |
11: 70,983,141 (GRCm39) |
Y1275F |
possibly damaging |
Het |
| Nova1 |
A |
T |
12: 46,767,618 (GRCm39) |
L8* |
probably null |
Het |
| Odam |
G |
T |
5: 88,037,967 (GRCm39) |
G181* |
probably null |
Het |
| Optn |
T |
A |
2: 5,026,190 (GRCm39) |
Q576L |
probably benign |
Het |
| Or2c1 |
T |
C |
16: 3,657,434 (GRCm39) |
L199P |
probably damaging |
Het |
| Or4k47 |
T |
C |
2: 111,451,879 (GRCm39) |
D180G |
probably damaging |
Het |
| Or4l1 |
C |
T |
14: 50,166,354 (GRCm39) |
V216I |
probably benign |
Het |
| Or51a39 |
A |
T |
7: 102,362,702 (GRCm39) |
I306N |
probably damaging |
Het |
| Or5as1 |
T |
A |
2: 86,981,003 (GRCm39) |
M1L |
possibly damaging |
Het |
| Or5h18 |
A |
T |
16: 58,847,696 (GRCm39) |
D191E |
probably damaging |
Het |
| Or8s2 |
T |
C |
15: 98,277,030 (GRCm39) |
|
probably benign |
Het |
| Patl2 |
G |
T |
2: 121,959,329 (GRCm39) |
S45* |
probably null |
Het |
| Pde2a |
G |
A |
7: 101,152,140 (GRCm39) |
G349E |
probably benign |
Het |
| Pdlim2 |
T |
A |
14: 70,405,464 (GRCm39) |
|
probably benign |
Het |
| Per1 |
T |
C |
11: 68,995,227 (GRCm39) |
V653A |
probably benign |
Het |
| Phlda2 |
A |
G |
7: 143,056,005 (GRCm39) |
S75P |
probably damaging |
Het |
| Poldip3 |
A |
T |
15: 83,021,706 (GRCm39) |
M167K |
possibly damaging |
Het |
| Potegl |
C |
A |
2: 23,135,127 (GRCm39) |
T312K |
probably benign |
Het |
| Prpf38a |
T |
C |
4: 108,436,278 (GRCm39) |
I12V |
probably benign |
Het |
| Prrc1 |
G |
A |
18: 57,507,622 (GRCm39) |
V259I |
possibly damaging |
Het |
| Ptges3l |
A |
T |
11: 101,315,448 (GRCm39) |
M1K |
probably null |
Het |
| Rdh5 |
A |
G |
10: 128,749,653 (GRCm39) |
Y296H |
probably damaging |
Het |
| Resf1 |
G |
T |
6: 149,229,896 (GRCm39) |
G981* |
probably null |
Het |
| Rnf2 |
T |
A |
1: 151,348,968 (GRCm39) |
K51* |
probably null |
Het |
| Rpusd3 |
C |
A |
6: 113,393,809 (GRCm39) |
R215L |
probably benign |
Het |
| Rsph4a |
A |
T |
10: 33,785,236 (GRCm39) |
E382D |
probably damaging |
Het |
| S1pr2 |
G |
A |
9: 20,879,745 (GRCm39) |
Q28* |
probably null |
Het |
| Sesn1 |
A |
T |
10: 41,771,005 (GRCm39) |
I179F |
probably damaging |
Het |
| Setd3 |
T |
A |
12: 108,079,630 (GRCm39) |
E291V |
probably benign |
Het |
| Shc1 |
G |
T |
3: 89,334,303 (GRCm39) |
R323L |
probably damaging |
Het |
| Slc22a5 |
T |
C |
11: 53,782,352 (GRCm39) |
D5G |
possibly damaging |
Het |
| Slc6a19 |
T |
C |
13: 73,848,677 (GRCm39) |
K26E |
probably benign |
Het |
| Slc9a3 |
A |
G |
13: 74,312,412 (GRCm39) |
N670D |
possibly damaging |
Het |
| Spata19 |
A |
T |
9: 27,311,761 (GRCm39) |
I127L |
probably benign |
Het |
| Speg |
G |
T |
1: 75,404,347 (GRCm39) |
V2751L |
probably damaging |
Het |
| Sptbn2 |
A |
G |
19: 4,779,337 (GRCm39) |
D298G |
probably benign |
Het |
| Srm |
T |
C |
4: 148,678,640 (GRCm39) |
V289A |
possibly damaging |
Het |
| Stip1 |
C |
T |
19: 7,012,938 (GRCm39) |
A49T |
probably benign |
Het |
| Tas2r118 |
C |
A |
6: 23,969,627 (GRCm39) |
V145F |
probably benign |
Het |
| Tbc1d12 |
A |
T |
19: 38,854,169 (GRCm39) |
K284* |
probably null |
Het |
| Tfcp2 |
T |
C |
15: 100,423,531 (GRCm39) |
H125R |
probably damaging |
Het |
| Tfdp1 |
T |
C |
8: 13,423,073 (GRCm39) |
V206A |
probably damaging |
Het |
| Tgtp2 |
A |
G |
11: 48,950,237 (GRCm39) |
W112R |
probably damaging |
Het |
| Tmem71 |
T |
G |
15: 66,410,710 (GRCm39) |
M221L |
probably benign |
Het |
| Tpcn1 |
T |
C |
5: 120,685,552 (GRCm39) |
N436S |
possibly damaging |
Het |
| Usp4 |
C |
T |
9: 108,239,819 (GRCm39) |
L183F |
probably damaging |
Het |
| Vmn2r55 |
A |
T |
7: 12,404,478 (GRCm39) |
N308K |
possibly damaging |
Het |
| Zfp108 |
A |
T |
7: 23,959,573 (GRCm39) |
I55L |
probably benign |
Het |
| Zfp512b |
A |
T |
2: 181,228,131 (GRCm39) |
S8R |
probably damaging |
Het |
| Zfp827 |
T |
C |
8: 79,787,910 (GRCm39) |
S359P |
probably benign |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,385,729 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,354,010 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,364,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,350,898 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,369,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACTGATGTGTCGGCTTAGATC -3'
(R):5'- TGAAGGTGTGGCTTCACTGAC -3'
Sequencing Primer
(F):5'- CTTAGATCTCTCTGGAGCGAGGC -3'
(R):5'- TGTGGCTTCACTGACCACAGAG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation