Incidental Mutation 'R4688:Pde4dip'
| ID |
353827 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pde4dip
|
| Ensembl Gene |
ENSMUSG00000038170 |
| Gene Name |
phosphodiesterase 4D interacting protein (myomegalin) |
| Synonyms |
Usmg4, D3Bwg1078e, D130016K21Rik, 9430063L05Rik, 4732458A06Rik |
| MMRRC Submission |
041939-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4688 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
97597144-97796023 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
T to A
at 97750993 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Stop codon
at position 74
(R74*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131170
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000090750]
[ENSMUST00000107038]
[ENSMUST00000168438]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000090750
AA Change: R74*
|
| SMART Domains |
Protein: ENSMUSP00000088254
Gene: ENSMUSG00000038170
AA Change: R74*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
45 |
57 |
N/A |
INTRINSIC |
|
Pfam:Cnn_1N
|
124 |
196 |
3.2e-26 |
PFAM |
|
low complexity region
|
204 |
219 |
N/A |
INTRINSIC |
|
coiled coil region
|
282 |
325 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
397 |
438 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
567 |
578 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
617 |
667 |
6.59e-5 |
PROSPERO |
|
internal_repeat_1
|
620 |
661 |
4.03e-5 |
PROSPERO |
|
coiled coil region
|
866 |
942 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1056 |
N/A |
INTRINSIC |
|
low complexity region
|
1067 |
1082 |
N/A |
INTRINSIC |
|
coiled coil region
|
1118 |
1163 |
N/A |
INTRINSIC |
|
coiled coil region
|
1336 |
1363 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1420 |
N/A |
INTRINSIC |
|
coiled coil region
|
1470 |
1508 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1597 |
1644 |
6.59e-5 |
PROSPERO |
|
DUF1220
|
1680 |
1747 |
1.17e-17 |
SMART |
|
low complexity region
|
1758 |
1780 |
N/A |
INTRINSIC |
|
low complexity region
|
1836 |
1851 |
N/A |
INTRINSIC |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1940 |
1951 |
N/A |
INTRINSIC |
|
coiled coil region
|
1962 |
2138 |
N/A |
INTRINSIC |
|
coiled coil region
|
2162 |
2197 |
N/A |
INTRINSIC |
|
coiled coil region
|
2387 |
2431 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107038
AA Change: R20*
|
| SMART Domains |
Protein: ENSMUSP00000102653
Gene: ENSMUSG00000038170
AA Change: R20*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Microtub_assoc
|
70 |
144 |
7.8e-32 |
PFAM |
|
low complexity region
|
150 |
165 |
N/A |
INTRINSIC |
|
coiled coil region
|
228 |
271 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
343 |
384 |
5.54e-5 |
PROSPERO |
|
low complexity region
|
513 |
524 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
566 |
607 |
5.54e-5 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000163531
|
| SMART Domains |
Protein: ENSMUSP00000132409
Gene: ENSMUSG00000038170
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Microtub_assoc
|
70 |
117 |
7.9e-21 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000168438
AA Change: R74*
|
| SMART Domains |
Protein: ENSMUSP00000131170
Gene: ENSMUSG00000038170
AA Change: R74*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
45 |
57 |
N/A |
INTRINSIC |
|
Pfam:Microtub_assoc
|
124 |
198 |
1.4e-31 |
PFAM |
|
low complexity region
|
204 |
219 |
N/A |
INTRINSIC |
|
coiled coil region
|
282 |
325 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
397 |
438 |
3.56e-5 |
PROSPERO |
|
low complexity region
|
567 |
578 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
617 |
667 |
5.83e-5 |
PROSPERO |
|
internal_repeat_1
|
620 |
661 |
3.56e-5 |
PROSPERO |
|
coiled coil region
|
866 |
942 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1056 |
N/A |
INTRINSIC |
|
low complexity region
|
1067 |
1082 |
N/A |
INTRINSIC |
|
coiled coil region
|
1118 |
1163 |
N/A |
INTRINSIC |
|
coiled coil region
|
1336 |
1363 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1420 |
N/A |
INTRINSIC |
|
coiled coil region
|
1470 |
1508 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
1597 |
1644 |
5.83e-5 |
PROSPERO |
|
DUF1220
|
1680 |
1747 |
1.17e-17 |
SMART |
|
low complexity region
|
1758 |
1769 |
N/A |
INTRINSIC |
|
low complexity region
|
1785 |
1800 |
N/A |
INTRINSIC |
|
low complexity region
|
1809 |
1823 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1900 |
N/A |
INTRINSIC |
|
coiled coil region
|
1911 |
2087 |
N/A |
INTRINSIC |
|
coiled coil region
|
2111 |
2146 |
N/A |
INTRINSIC |
|
coiled coil region
|
2336 |
2380 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
PHENOTYPE: Mice homozygous for a null allele exhibit partial (in utero or perinatal) lethality, hyperactivity, and increased vertical activity. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003E16Rik |
A |
G |
6: 83,139,680 (GRCm39) |
N535S |
probably damaging |
Het |
| Abcc12 |
T |
C |
8: 87,275,323 (GRCm39) |
S452G |
possibly damaging |
Het |
| Acacb |
C |
A |
5: 114,342,824 (GRCm39) |
Q897K |
probably benign |
Het |
| Acot3 |
C |
A |
12: 84,100,691 (GRCm39) |
R145S |
probably damaging |
Het |
| Ankrd54 |
A |
T |
15: 78,938,782 (GRCm39) |
Y247N |
probably damaging |
Het |
| Arl11 |
G |
A |
14: 61,548,546 (GRCm39) |
V119I |
probably benign |
Het |
| Atosb |
A |
G |
4: 43,034,663 (GRCm39) |
F352S |
probably damaging |
Het |
| Atxn7 |
T |
A |
14: 14,089,288 (GRCm38) |
M268K |
probably benign |
Het |
| Bms1 |
G |
A |
6: 118,369,667 (GRCm39) |
R934C |
probably damaging |
Het |
| Brd10 |
A |
G |
19: 29,694,501 (GRCm39) |
I1664T |
probably benign |
Het |
| Chrnb3 |
T |
C |
8: 27,884,147 (GRCm39) |
S295P |
probably damaging |
Het |
| Cic |
TCCCCC |
TCCCCCCC |
7: 24,991,095 (GRCm39) |
|
probably null |
Het |
| Cnr1 |
A |
T |
4: 33,944,571 (GRCm39) |
I320F |
probably benign |
Het |
| Cntn4 |
C |
T |
6: 106,414,910 (GRCm39) |
P147L |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,020,144 (GRCm39) |
V172I |
probably benign |
Het |
| Col9a3 |
A |
G |
2: 180,249,424 (GRCm39) |
D262G |
probably damaging |
Het |
| Csrnp2 |
A |
G |
15: 100,380,241 (GRCm39) |
V350A |
probably damaging |
Het |
| D630045J12Rik |
A |
G |
6: 38,173,592 (GRCm39) |
V192A |
possibly damaging |
Het |
| Deptor |
A |
G |
15: 55,072,177 (GRCm39) |
M219V |
probably benign |
Het |
| Dmrtb1 |
A |
T |
4: 107,541,247 (GRCm39) |
L38Q |
probably damaging |
Het |
| Dvl2 |
G |
A |
11: 69,898,344 (GRCm39) |
R367Q |
possibly damaging |
Het |
| Dync1h1 |
T |
G |
12: 110,621,962 (GRCm39) |
I3435S |
probably damaging |
Het |
| Ecpas |
A |
G |
4: 58,840,757 (GRCm39) |
V667A |
probably damaging |
Het |
| Eif2b3 |
A |
G |
4: 116,916,046 (GRCm39) |
N218D |
probably benign |
Het |
| Epha2 |
A |
G |
4: 141,046,292 (GRCm39) |
D497G |
probably benign |
Het |
| Epha7 |
G |
T |
4: 28,821,367 (GRCm39) |
L177F |
probably damaging |
Het |
| Fam98c |
C |
T |
7: 28,854,666 (GRCm39) |
E147K |
probably damaging |
Het |
| Fbxo17 |
A |
G |
7: 28,431,979 (GRCm39) |
T19A |
probably benign |
Het |
| Fbxo47 |
A |
G |
11: 97,747,049 (GRCm39) |
F339S |
probably damaging |
Het |
| Frmd4a |
G |
T |
2: 4,542,122 (GRCm39) |
V234L |
possibly damaging |
Het |
| Gal3st2 |
A |
G |
1: 93,800,245 (GRCm39) |
D32G |
probably damaging |
Het |
| Gpr135 |
T |
C |
12: 72,117,720 (GRCm39) |
T16A |
probably benign |
Het |
| Gpr160 |
A |
T |
3: 30,950,835 (GRCm39) |
R302S |
probably benign |
Het |
| Hrh2 |
C |
A |
13: 54,368,820 (GRCm39) |
N265K |
probably benign |
Het |
| Htatip2 |
C |
A |
7: 49,423,171 (GRCm39) |
A242E |
probably damaging |
Het |
| Igfbp7 |
T |
C |
5: 77,555,482 (GRCm39) |
Y127C |
probably damaging |
Het |
| Igkv16-104 |
A |
G |
6: 68,402,878 (GRCm39) |
Q57R |
possibly damaging |
Het |
| Ino80c |
A |
G |
18: 24,241,903 (GRCm39) |
S161P |
probably damaging |
Het |
| Itprid1 |
G |
A |
6: 55,944,132 (GRCm39) |
|
probably null |
Het |
| Kcnc1 |
A |
G |
7: 46,047,259 (GRCm39) |
D53G |
probably benign |
Het |
| Khdc4 |
T |
A |
3: 88,593,824 (GRCm39) |
M71K |
probably damaging |
Het |
| Lce1h |
G |
T |
3: 92,670,874 (GRCm39) |
R93S |
unknown |
Het |
| Lce1k |
T |
C |
3: 92,713,951 (GRCm39) |
S78G |
unknown |
Het |
| Lhcgr |
T |
A |
17: 89,072,580 (GRCm39) |
I156F |
probably damaging |
Het |
| Lpl |
T |
C |
8: 69,352,077 (GRCm39) |
Y343H |
probably damaging |
Het |
| Lrp6 |
G |
T |
6: 134,456,706 (GRCm39) |
R853S |
probably damaging |
Het |
| Lrrc7 |
A |
G |
3: 157,854,242 (GRCm39) |
V1322A |
probably damaging |
Het |
| Lrrc74a |
C |
T |
12: 86,784,472 (GRCm39) |
Q67* |
probably null |
Het |
| Megf6 |
A |
T |
4: 154,338,271 (GRCm39) |
D447V |
probably damaging |
Het |
| Mep1a |
T |
C |
17: 43,793,139 (GRCm39) |
D355G |
possibly damaging |
Het |
| Ncoa1 |
T |
C |
12: 4,365,781 (GRCm39) |
D95G |
probably benign |
Het |
| Npepl1 |
A |
T |
2: 173,956,235 (GRCm39) |
I139F |
possibly damaging |
Het |
| Nrcam |
T |
C |
12: 44,594,020 (GRCm39) |
S262P |
probably benign |
Het |
| Nrp1 |
A |
G |
8: 129,229,047 (GRCm39) |
N842D |
probably benign |
Het |
| Olfml3 |
A |
G |
3: 103,639,497 (GRCm39) |
|
probably benign |
Het |
| Or1x6 |
A |
G |
11: 50,939,815 (GRCm39) |
R294G |
probably damaging |
Het |
| Or4b1d |
T |
A |
2: 89,969,343 (GRCm39) |
N47Y |
possibly damaging |
Het |
| Or6b6 |
T |
A |
7: 106,571,068 (GRCm39) |
Y161F |
probably benign |
Het |
| Or6c204 |
G |
A |
10: 129,022,514 (GRCm39) |
P259S |
probably damaging |
Het |
| Or6k8-ps1 |
T |
C |
1: 173,979,162 (GRCm39) |
Y27H |
possibly damaging |
Het |
| Or8b3b |
A |
G |
9: 38,584,659 (GRCm39) |
L27P |
probably damaging |
Het |
| Or9i1b |
A |
T |
19: 13,896,605 (GRCm39) |
T74S |
probably benign |
Het |
| Pde2a |
A |
G |
7: 101,152,041 (GRCm39) |
N316S |
probably benign |
Het |
| Pex13 |
A |
T |
11: 23,605,472 (GRCm39) |
W253R |
possibly damaging |
Het |
| Piezo1 |
A |
T |
8: 123,215,278 (GRCm39) |
W1444R |
probably damaging |
Het |
| Pla2g4e |
T |
C |
2: 119,998,414 (GRCm39) |
K843R |
possibly damaging |
Het |
| Plxna2 |
C |
T |
1: 194,326,753 (GRCm39) |
P229L |
probably damaging |
Het |
| Prelid3b |
G |
T |
2: 174,308,592 (GRCm39) |
T131K |
probably benign |
Het |
| Pros1 |
T |
C |
16: 62,709,370 (GRCm39) |
|
probably null |
Het |
| Prrc2c |
G |
T |
1: 162,525,256 (GRCm39) |
P450Q |
unknown |
Het |
| Ptbp1 |
G |
T |
10: 79,692,342 (GRCm39) |
V5F |
possibly damaging |
Het |
| Ptk2 |
T |
A |
15: 73,078,074 (GRCm39) |
L997F |
probably damaging |
Het |
| Rims1 |
G |
T |
1: 22,518,528 (GRCm39) |
S525* |
probably null |
Het |
| Sanbr |
A |
G |
11: 23,543,449 (GRCm39) |
S530P |
probably benign |
Het |
| Sh2b3 |
T |
A |
5: 121,956,697 (GRCm39) |
D318V |
probably benign |
Het |
| Slc16a13 |
A |
T |
11: 70,111,101 (GRCm39) |
I88N |
probably damaging |
Het |
| Slit2 |
T |
A |
5: 48,414,345 (GRCm39) |
|
probably null |
Het |
| Snx10 |
A |
G |
6: 51,556,918 (GRCm39) |
N67S |
probably damaging |
Het |
| Stil |
A |
G |
4: 114,898,505 (GRCm39) |
Y1045C |
probably damaging |
Het |
| Stra6 |
A |
G |
9: 58,042,359 (GRCm39) |
|
probably null |
Het |
| Sympk |
A |
G |
7: 18,788,335 (GRCm39) |
S1254G |
probably benign |
Het |
| Syt15 |
G |
T |
14: 33,950,011 (GRCm39) |
G377V |
probably damaging |
Het |
| Taar4 |
A |
T |
10: 23,836,731 (GRCm39) |
I114F |
probably damaging |
Het |
| Tcaf3 |
G |
A |
6: 42,570,300 (GRCm39) |
|
probably null |
Het |
| Tgm7 |
A |
T |
2: 120,924,502 (GRCm39) |
N558K |
probably benign |
Het |
| Tln2 |
T |
G |
9: 67,304,935 (GRCm39) |
M1L |
probably benign |
Het |
| Trim50 |
C |
T |
5: 135,395,994 (GRCm39) |
T314I |
probably damaging |
Het |
| Trp53rka |
A |
T |
2: 165,333,312 (GRCm39) |
Y192* |
probably null |
Het |
| Ube3b |
T |
C |
5: 114,531,139 (GRCm39) |
V211A |
probably benign |
Het |
| Ush2a |
A |
G |
1: 188,132,138 (GRCm39) |
S787G |
probably benign |
Het |
| Vmn1r189 |
T |
C |
13: 22,286,289 (GRCm39) |
M183V |
probably damaging |
Het |
| Vps13d |
G |
T |
4: 144,904,782 (GRCm39) |
Q115K |
probably benign |
Het |
| Zfp358 |
A |
G |
8: 3,545,493 (GRCm39) |
D25G |
probably damaging |
Het |
| Zfp521 |
T |
G |
18: 13,977,647 (GRCm39) |
K922T |
probably damaging |
Het |
| Zfp521 |
T |
A |
18: 13,977,648 (GRCm39) |
K922* |
probably null |
Het |
| Zfp68 |
T |
A |
5: 138,614,743 (GRCm39) |
K4* |
probably null |
Het |
|
| Other mutations in Pde4dip |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00332:Pde4dip
|
APN |
3 |
97,674,593 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00543:Pde4dip
|
APN |
3 |
97,664,940 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL00979:Pde4dip
|
APN |
3 |
97,655,074 (GRCm39) |
splice site |
probably benign |
|
|
IGL01483:Pde4dip
|
APN |
3 |
97,661,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02122:Pde4dip
|
APN |
3 |
97,674,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02398:Pde4dip
|
APN |
3 |
97,674,097 (GRCm39) |
missense |
probably benign |
|
|
IGL02814:Pde4dip
|
APN |
3 |
97,674,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02826:Pde4dip
|
APN |
3 |
97,674,403 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Pde4dip
|
UTSW |
3 |
97,674,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Pde4dip
|
UTSW |
3 |
97,660,442 (GRCm39) |
nonsense |
probably null |
|
|
R0096:Pde4dip
|
UTSW |
3 |
97,674,783 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0277:Pde4dip
|
UTSW |
3 |
97,751,028 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0304:Pde4dip
|
UTSW |
3 |
97,751,028 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0616:Pde4dip
|
UTSW |
3 |
97,654,849 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0676:Pde4dip
|
UTSW |
3 |
97,624,413 (GRCm39) |
splice site |
probably benign |
|
|
R1166:Pde4dip
|
UTSW |
3 |
97,620,512 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1376:Pde4dip
|
UTSW |
3 |
97,650,533 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1376:Pde4dip
|
UTSW |
3 |
97,650,533 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1452:Pde4dip
|
UTSW |
3 |
97,631,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Pde4dip
|
UTSW |
3 |
97,627,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1700:Pde4dip
|
UTSW |
3 |
97,610,639 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1704:Pde4dip
|
UTSW |
3 |
97,661,576 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1769:Pde4dip
|
UTSW |
3 |
97,603,246 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1934:Pde4dip
|
UTSW |
3 |
97,600,007 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1980:Pde4dip
|
UTSW |
3 |
97,664,312 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2088:Pde4dip
|
UTSW |
3 |
97,661,749 (GRCm39) |
missense |
probably null |
1.00 |
|
R2143:Pde4dip
|
UTSW |
3 |
97,795,835 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2149:Pde4dip
|
UTSW |
3 |
97,700,152 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R2156:Pde4dip
|
UTSW |
3 |
97,631,534 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2158:Pde4dip
|
UTSW |
3 |
97,664,937 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2240:Pde4dip
|
UTSW |
3 |
97,631,480 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2249:Pde4dip
|
UTSW |
3 |
97,700,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Pde4dip
|
UTSW |
3 |
97,625,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2680:Pde4dip
|
UTSW |
3 |
97,608,933 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2921:Pde4dip
|
UTSW |
3 |
97,626,885 (GRCm39) |
missense |
probably benign |
|
|
R3407:Pde4dip
|
UTSW |
3 |
97,661,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3736:Pde4dip
|
UTSW |
3 |
97,631,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3787:Pde4dip
|
UTSW |
3 |
97,622,868 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R3883:Pde4dip
|
UTSW |
3 |
97,620,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4437:Pde4dip
|
UTSW |
3 |
97,673,885 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4528:Pde4dip
|
UTSW |
3 |
97,624,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Pde4dip
|
UTSW |
3 |
97,661,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4600:Pde4dip
|
UTSW |
3 |
97,603,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4653:Pde4dip
|
UTSW |
3 |
97,674,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4678:Pde4dip
|
UTSW |
3 |
97,602,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4679:Pde4dip
|
UTSW |
3 |
97,602,321 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4770:Pde4dip
|
UTSW |
3 |
97,674,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4841:Pde4dip
|
UTSW |
3 |
97,700,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4842:Pde4dip
|
UTSW |
3 |
97,700,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4899:Pde4dip
|
UTSW |
3 |
97,616,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4914:Pde4dip
|
UTSW |
3 |
97,622,644 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4943:Pde4dip
|
UTSW |
3 |
97,662,827 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5131:Pde4dip
|
UTSW |
3 |
97,616,830 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5408:Pde4dip
|
UTSW |
3 |
97,704,052 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5583:Pde4dip
|
UTSW |
3 |
97,654,892 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5677:Pde4dip
|
UTSW |
3 |
97,748,964 (GRCm39) |
nonsense |
probably null |
|
|
R5689:Pde4dip
|
UTSW |
3 |
97,599,683 (GRCm39) |
nonsense |
probably null |
|
|
R5696:Pde4dip
|
UTSW |
3 |
97,616,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5860:Pde4dip
|
UTSW |
3 |
97,631,504 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6279:Pde4dip
|
UTSW |
3 |
97,606,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6341:Pde4dip
|
UTSW |
3 |
97,602,227 (GRCm39) |
missense |
probably benign |
|
|
R6440:Pde4dip
|
UTSW |
3 |
97,674,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6464:Pde4dip
|
UTSW |
3 |
97,617,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6489:Pde4dip
|
UTSW |
3 |
97,662,907 (GRCm39) |
nonsense |
probably null |
|
|
R6706:Pde4dip
|
UTSW |
3 |
97,648,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6722:Pde4dip
|
UTSW |
3 |
97,625,555 (GRCm39) |
nonsense |
probably null |
|
|
R6798:Pde4dip
|
UTSW |
3 |
97,795,850 (GRCm39) |
missense |
probably benign |
|
|
R6804:Pde4dip
|
UTSW |
3 |
97,700,564 (GRCm39) |
nonsense |
probably null |
|
|
R6862:Pde4dip
|
UTSW |
3 |
97,674,340 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6957:Pde4dip
|
UTSW |
3 |
97,731,649 (GRCm39) |
splice site |
probably null |
|
|
R6983:Pde4dip
|
UTSW |
3 |
97,625,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7014:Pde4dip
|
UTSW |
3 |
97,622,738 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7025:Pde4dip
|
UTSW |
3 |
97,631,499 (GRCm39) |
nonsense |
probably null |
|
|
R7136:Pde4dip
|
UTSW |
3 |
97,601,379 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7178:Pde4dip
|
UTSW |
3 |
97,622,946 (GRCm39) |
missense |
probably benign |
0.26 |
|
R7269:Pde4dip
|
UTSW |
3 |
97,674,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Pde4dip
|
UTSW |
3 |
97,666,198 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7354:Pde4dip
|
UTSW |
3 |
97,626,646 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7357:Pde4dip
|
UTSW |
3 |
97,622,857 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7360:Pde4dip
|
UTSW |
3 |
97,625,632 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7371:Pde4dip
|
UTSW |
3 |
97,664,587 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7432:Pde4dip
|
UTSW |
3 |
97,602,408 (GRCm39) |
missense |
probably benign |
|
|
R7536:Pde4dip
|
UTSW |
3 |
97,664,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7542:Pde4dip
|
UTSW |
3 |
97,673,971 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7609:Pde4dip
|
UTSW |
3 |
97,622,881 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7650:Pde4dip
|
UTSW |
3 |
97,606,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7800:Pde4dip
|
UTSW |
3 |
97,622,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7846:Pde4dip
|
UTSW |
3 |
97,622,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7918:Pde4dip
|
UTSW |
3 |
97,622,539 (GRCm39) |
nonsense |
probably null |
|
|
R8120:Pde4dip
|
UTSW |
3 |
97,614,254 (GRCm39) |
missense |
probably null |
0.94 |
|
R8139:Pde4dip
|
UTSW |
3 |
97,604,309 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8144:Pde4dip
|
UTSW |
3 |
97,622,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8177:Pde4dip
|
UTSW |
3 |
97,674,848 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8294:Pde4dip
|
UTSW |
3 |
97,674,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8406:Pde4dip
|
UTSW |
3 |
97,606,428 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8911:Pde4dip
|
UTSW |
3 |
97,650,917 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8912:Pde4dip
|
UTSW |
3 |
97,617,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8960:Pde4dip
|
UTSW |
3 |
97,700,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8993:Pde4dip
|
UTSW |
3 |
97,673,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9031:Pde4dip
|
UTSW |
3 |
97,599,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9032:Pde4dip
|
UTSW |
3 |
97,601,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9085:Pde4dip
|
UTSW |
3 |
97,601,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9103:Pde4dip
|
UTSW |
3 |
97,749,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9163:Pde4dip
|
UTSW |
3 |
97,659,123 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9182:Pde4dip
|
UTSW |
3 |
97,602,314 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9185:Pde4dip
|
UTSW |
3 |
97,666,132 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9286:Pde4dip
|
UTSW |
3 |
97,607,183 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9357:Pde4dip
|
UTSW |
3 |
97,625,645 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9415:Pde4dip
|
UTSW |
3 |
97,660,468 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9500:Pde4dip
|
UTSW |
3 |
97,795,896 (GRCm39) |
missense |
unknown |
|
|
R9595:Pde4dip
|
UTSW |
3 |
97,602,207 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9689:Pde4dip
|
UTSW |
3 |
97,649,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9720:Pde4dip
|
UTSW |
3 |
97,603,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAGGCGATTTCCAACTAGGG -3'
(R):5'- TAAAGTCTGTCTCACCAAGCCC -3'
Sequencing Primer
(F):5'- CTCCCATTATGGACTGGA -3'
(R):5'- TGTCTCACCAAGCCCTTACAC -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation