Incidental Mutation 'N/A:1700016P04Rik'
ID 31
Institutional Source Beutler Lab
Gene Symbol 1700016P04Rik
Ensembl Gene ENSMUSG00000101894
Gene Name RIKEN cDNA 1700016P04 gene
Synonyms
Accession Numbers
Essential gene? Not available question?
Stock # N/A of strain 294
Quality Score
Status Validated
Chromosome 6
Chromosomal Location 13413336-13415995 bp(+) (GRCm39)
Type of Mutation splice site
DNA Base Change (assembly) T to A at 13415772 bp (GRCm39)
Zygosity Homozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000186770
Coding Region Coverage
  • 1x: 88.7%
  • 3x: 76.0%
Validation Efficiency 91% (106/116)
Allele List at MGI
Other mutations in this stock
Total: 18 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aif1 A G 17: 35,391,496 (GRCm39) L7S possibly damaging Homo
Ankrd26 T C 6: 118,506,535 (GRCm39) D646G probably benign Homo
Cacna1s A G 1: 136,001,247 (GRCm39) I233V probably benign Homo
Cfap92 A T 6: 87,667,773 (GRCm39) noncoding transcript Homo
Chchd4 T C 6: 91,442,187 (GRCm39) Y77C probably damaging Homo
Crocc G A 4: 140,749,057 (GRCm39) R1419C probably damaging Homo
Cyp4f39 A C 17: 32,687,655 (GRCm39) M74L probably benign Homo
Fgf9 C A 14: 58,327,421 (GRCm39) probably benign Homo
Gimap6 T C 6: 48,679,349 (GRCm39) D229G probably damaging Homo
Glp1r T C 17: 31,150,257 (GRCm39) F393S probably damaging Homo
Lrrc7 T G 3: 157,865,977 (GRCm39) I1255L probably benign Homo
Mtrr C A 13: 68,723,516 (GRCm39) probably benign Homo
Pde6b A T 5: 108,576,969 (GRCm39) probably benign Homo
Rbm19 A T 5: 120,282,162 (GRCm39) I840F probably damaging Homo
Serpina3c A C 12: 104,115,864 (GRCm39) S227A probably benign Homo
Spag17 G A 3: 99,889,570 (GRCm39) probably benign Homo
Spmip3 G A 1: 177,561,100 (GRCm39) R13H probably damaging Homo
Zbtb8b T C 4: 129,326,361 (GRCm39) D268G probably benign Homo
Nature of Mutation
DNA sequencing using the SOLiD technique identified a T to A transversion at position 2439 in the Genbank genomic region NC_000072 for the 1700016P04Rik gene on chromosome 6 (TTGATTTTAG ->TAGATTTTAG). The mutation is located nine nucleotides upstream from the start of the exon, and may impair the acceptor splice site.  The 1700016P04Rik transcript record was removed as a result of standard genome annotation processing. The mutation has been confirmed by DNA sequencing using the Sanger method (Figure 1).
Protein Function and Prediction

1700016P04Rik is an uncharacterized gene that encodes a 69 amino acid hypothetical protein. The SMART program predicts a signal peptide at amino acids 1-21.

Posted On 2009-11-06