Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02547:Zfp1007'

297896

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp1007

Ensembl Gene

ENSMUSG00000072763

Gene Name

zinc finger protein 1007

Synonyms

5430403G16Rik, ENSMUSG00000072763

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.113) question?

Stock #

IGL02547

Quality Score

Status

Chromosome

Chromosomal Location

109822409-109838700 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (1 bp from exon)

DNA Base Change (assembly)

C to T at 109826628 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000090395 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092720]

AlphaFold

D3Z5L4

Predicted Effect

probably null
Transcript: ENSMUST00000092720

SMART Domains

Protein: ENSMUSP00000090395
Gene: ENSMUSG00000072763

Domain	Start	End	E-Value	Type
KRAB	4	60	2.47e-14	SMART
ZnF_C2H2	131	153	3.39e-3	SMART
ZnF_C2H2	159	181	3.95e-4	SMART
ZnF_C2H2	187	209	3.95e-4	SMART
ZnF_C2H2	215	237	1.12e-3	SMART
ZnF_C2H2	243	265	4.01e-5	SMART
ZnF_C2H2	271	293	7.78e-3	SMART
ZnF_C2H2	299	321	2.61e-4	SMART
ZnF_C2H2	327	349	1.36e-2	SMART
ZnF_C2H2	355	377	7.37e-4	SMART
ZnF_C2H2	383	405	1.3e-4	SMART
ZnF_C2H2	411	433	3.69e-4	SMART
ZnF_C2H2	439	461	4.3e-5	SMART
ZnF_C2H2	467	489	2.57e-3	SMART
ZnF_C2H2	495	517	2.61e-4	SMART
ZnF_C2H2	523	545	2.05e-2	SMART
ZnF_C2H2	551	573	5.59e-4	SMART
ZnF_C2H2	579	601	1.58e-3	SMART
ZnF_C2H2	607	629	9.08e-4	SMART
ZnF_C2H2	635	657	3.44e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 51 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Akap6	T	A	12: 53,187,479 (GRCm39)	L1631H	probably damaging	Het
Atf7ip	T	A	6: 136,580,274 (GRCm39)		probably benign	Het
Atp5po	A	T	16: 91,725,849 (GRCm39)	Y48N	probably damaging	Het
Birc6	T	G	17: 74,886,640 (GRCm39)	M656R	probably benign	Het
Camkk1	A	G	11: 72,929,259 (GRCm39)	R455G	probably benign	Het
Casr	A	T	16: 36,336,036 (GRCm39)	M91K	probably benign	Het
Ccdc28a	A	T	10: 18,089,894 (GRCm39)	V124D	possibly damaging	Het
Ccnh	T	C	13: 85,350,623 (GRCm39)		probably benign	Het
Cdc37	G	T	9: 21,051,262 (GRCm39)		probably benign	Het
Cdon	A	G	9: 35,389,950 (GRCm39)	D868G	probably damaging	Het
Cstdc3	A	T	16: 36,132,888 (GRCm39)		probably benign	Het
Cyp4f15	A	G	17: 32,919,229 (GRCm39)	R351G	probably benign	Het
Dclk3	T	C	9: 111,298,091 (GRCm39)	I545T	probably damaging	Het
Dock4	A	G	12: 40,787,478 (GRCm39)	M798V	probably benign	Het
Gas7	A	T	11: 67,556,261 (GRCm39)	Q200L	probably damaging	Het
Ica1	T	C	6: 8,670,691 (GRCm39)		probably null	Het
Idh3a	T	A	9: 54,499,679 (GRCm39)	V31D	probably benign	Het
Il3ra	A	T	14: 14,351,970 (GRCm38)	T247S	probably benign	Het
Itgb7	A	G	15: 102,126,945 (GRCm39)	C497R	probably damaging	Het
Itm2c	T	C	1: 85,834,182 (GRCm39)	Y166H	probably damaging	Het
Mphosph8	A	G	14: 56,909,941 (GRCm39)	D98G	probably damaging	Het
Mstn	A	T	1: 53,103,284 (GRCm39)	I207F	probably benign	Het
Muc15	A	G	2: 110,561,650 (GRCm39)	R29G	probably damaging	Het
Neb	T	A	2: 52,078,742 (GRCm39)	T142S	probably damaging	Het
Nipbl	G	A	15: 8,381,082 (GRCm39)	T570I	probably benign	Het
Nr5a2	T	A	1: 136,868,665 (GRCm39)	M196L	probably benign	Het
Nrp1	C	A	8: 129,219,512 (GRCm39)	F643L	probably benign	Het
Or52ad1	A	G	7: 102,995,451 (GRCm39)	F228S	probably damaging	Het
Or52z15	T	C	7: 103,331,973 (GRCm39)	I16T	probably benign	Het
Or5a3	A	T	19: 12,399,675 (GRCm39)	M1L	probably benign	Het
Or8h8	A	G	2: 86,753,372 (GRCm39)	F168S	probably damaging	Het
Osbpl9	C	T	4: 108,925,680 (GRCm39)	W446*	probably null	Het
Pced1a	T	C	2: 130,261,627 (GRCm39)	D342G	possibly damaging	Het
Pira13	T	C	7: 3,824,660 (GRCm39)	D573G	probably damaging	Het
Prkcd	C	A	14: 30,321,426 (GRCm39)	W555L	probably damaging	Het
Prpf31	T	C	7: 3,633,898 (GRCm39)	S78P	probably benign	Het
Psg27	T	C	7: 18,294,553 (GRCm39)	T285A	probably benign	Het
Retreg3	A	T	11: 100,997,204 (GRCm39)	L92*	probably null	Het
Rmdn1	A	G	4: 19,605,501 (GRCm39)	K282E	possibly damaging	Het
Septin8	G	T	11: 53,428,092 (GRCm39)	R302L	probably damaging	Het
Serpina3a	A	G	12: 104,082,802 (GRCm39)	I192V	probably damaging	Het
Sgce	T	C	6: 4,711,301 (GRCm39)		probably benign	Het
Slco1a8	A	T	6: 141,936,116 (GRCm39)	L323Q	probably damaging	Het
Spats1	A	T	17: 45,785,743 (GRCm39)		probably benign	Het
Tcerg1l	C	T	7: 137,850,100 (GRCm39)		probably null	Het
Ttn	A	G	2: 76,559,730 (GRCm39)	V21230A	probably damaging	Het
Ubxn11	A	C	4: 133,836,895 (GRCm39)	D41A	possibly damaging	Het
Vps13c	T	G	9: 67,815,301 (GRCm39)	I979S	possibly damaging	Het
Zc3h6	T	A	2: 128,857,531 (GRCm39)	H683Q	probably benign	Het
Zfp518a	G	A	19: 40,903,061 (GRCm39)	G997R	probably damaging	Het
Zfp629	T	C	7: 127,210,846 (GRCm39)		probably null	Het

Other mutations in Zfp1007

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01653:Zfp1007	APN	5	109,825,182 (GRCm39)	nonsense	probably null
IGL02589:Zfp1007	APN	5	109,826,386 (GRCm39)	missense	possibly damaging	0.95
BB007:Zfp1007	UTSW	5	109,823,622 (GRCm39)	nonsense	probably null
BB017:Zfp1007	UTSW	5	109,823,622 (GRCm39)	nonsense	probably null
R0363:Zfp1007	UTSW	5	109,824,754 (GRCm39)	missense	probably benign	0.03
R0628:Zfp1007	UTSW	5	109,826,442 (GRCm39)	critical splice acceptor site	probably null
R2858:Zfp1007	UTSW	5	109,823,819 (GRCm39)	missense	probably benign	0.02
R4914:Zfp1007	UTSW	5	109,826,396 (GRCm39)	missense	probably damaging	1.00
R4945:Zfp1007	UTSW	5	109,824,941 (GRCm39)	missense	possibly damaging	0.60
R5444:Zfp1007	UTSW	5	109,823,502 (GRCm39)	nonsense	probably null
R6000:Zfp1007	UTSW	5	109,824,730 (GRCm39)	missense	probably benign	0.19
R6258:Zfp1007	UTSW	5	109,824,433 (GRCm39)	missense	probably benign	0.01
R6389:Zfp1007	UTSW	5	109,823,885 (GRCm39)	missense	possibly damaging	0.84
R6945:Zfp1007	UTSW	5	109,824,711 (GRCm39)	missense	probably benign	0.25
R7225:Zfp1007	UTSW	5	109,825,015 (GRCm39)	missense	possibly damaging	0.69
R7581:Zfp1007	UTSW	5	109,838,654 (GRCm39)	start gained	probably benign
R7810:Zfp1007	UTSW	5	109,825,170 (GRCm39)	nonsense	probably null
R7930:Zfp1007	UTSW	5	109,823,622 (GRCm39)	nonsense	probably null
R8821:Zfp1007	UTSW	5	109,824,174 (GRCm39)	missense	probably benign	0.00
R8825:Zfp1007	UTSW	5	109,826,746 (GRCm39)	missense	probably damaging	1.00
R8831:Zfp1007	UTSW	5	109,824,174 (GRCm39)	missense	probably benign	0.00
R9179:Zfp1007	UTSW	5	109,823,708 (GRCm39)	missense	probably damaging	1.00
R9429:Zfp1007	UTSW	5	109,824,334 (GRCm39)	nonsense	probably null
R9486:Zfp1007	UTSW	5	109,824,062 (GRCm39)	nonsense	probably null
R9496:Zfp1007	UTSW	5	109,823,924 (GRCm39)	missense	probably damaging	0.98
R9525:Zfp1007	UTSW	5	109,824,846 (GRCm39)	missense

Posted On

2015-04-16