Incidental Mutation 'R2102:Plxnb1'
| ID |
230590 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
040106-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2102 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 108944810 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 2051
(M2051K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072093
AA Change: M2051K
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: M2051K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.3%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 85 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
T |
C |
3: 137,770,934 (GRCm39) |
L41P |
probably damaging |
Het |
| Abca8a |
G |
T |
11: 109,958,878 (GRCm39) |
P749T |
probably damaging |
Het |
| Acad8 |
A |
T |
9: 26,896,861 (GRCm39) |
Y199* |
probably null |
Het |
| Acot12 |
A |
T |
13: 91,908,096 (GRCm39) |
I93L |
probably benign |
Het |
| Acsbg3 |
T |
A |
17: 57,191,949 (GRCm39) |
Y542* |
probably null |
Het |
| Actn1 |
C |
A |
12: 80,230,291 (GRCm39) |
R321L |
probably benign |
Het |
| Ap3s1 |
A |
G |
18: 46,887,469 (GRCm39) |
E34G |
possibly damaging |
Het |
| Armh4 |
A |
G |
14: 50,011,459 (GRCm39) |
Y83H |
probably damaging |
Het |
| Atp5f1a |
T |
C |
18: 77,870,017 (GRCm39) |
S533P |
probably damaging |
Het |
| Bcorl1 |
T |
C |
X: 47,458,081 (GRCm39) |
V538A |
probably benign |
Het |
| Cdhr4 |
A |
G |
9: 107,875,206 (GRCm39) |
T689A |
probably damaging |
Het |
| Cdk19 |
A |
T |
10: 40,355,726 (GRCm39) |
|
probably benign |
Het |
| Cobll1 |
G |
T |
2: 64,928,554 (GRCm39) |
P923Q |
probably damaging |
Het |
| Cpt1a |
T |
C |
19: 3,421,585 (GRCm39) |
S456P |
probably benign |
Het |
| Cst11 |
T |
C |
2: 148,613,160 (GRCm39) |
Y55C |
probably damaging |
Het |
| Ctif |
T |
G |
18: 75,654,452 (GRCm39) |
D358A |
probably benign |
Het |
| Cyp2d34 |
T |
G |
15: 82,500,974 (GRCm39) |
E386A |
probably benign |
Het |
| Dcxr |
A |
G |
11: 120,617,133 (GRCm39) |
F104L |
probably benign |
Het |
| Dmbt1 |
G |
T |
7: 130,703,762 (GRCm39) |
W1107C |
probably damaging |
Het |
| Dsg1a |
A |
T |
18: 20,466,830 (GRCm39) |
I567F |
probably damaging |
Het |
| Ednrb |
T |
A |
14: 104,058,350 (GRCm39) |
R318* |
probably null |
Het |
| Exd2 |
T |
C |
12: 80,527,377 (GRCm39) |
I36T |
possibly damaging |
Het |
| Fam83b |
A |
T |
9: 76,399,987 (GRCm39) |
I372N |
probably damaging |
Het |
| Fbh1 |
A |
G |
2: 11,763,100 (GRCm39) |
V518A |
probably benign |
Het |
| Fkbp5 |
T |
C |
17: 28,625,162 (GRCm39) |
E308G |
possibly damaging |
Het |
| Foxl2 |
A |
C |
9: 98,838,282 (GRCm39) |
Y190S |
probably damaging |
Het |
| Gab3 |
TTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTC |
TTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTCTTC |
X: 74,043,585 (GRCm39) |
|
probably benign |
Het |
| Galnt17 |
C |
T |
5: 131,114,831 (GRCm39) |
R223Q |
probably damaging |
Het |
| Gm14496 |
G |
A |
2: 181,633,127 (GRCm39) |
D37N |
possibly damaging |
Het |
| Gpr82 |
T |
C |
X: 13,532,274 (GRCm39) |
V274A |
probably benign |
Het |
| Hsp90aa1 |
T |
C |
12: 110,660,566 (GRCm39) |
N292S |
probably damaging |
Het |
| Ints1 |
C |
T |
5: 139,741,754 (GRCm39) |
V1826M |
possibly damaging |
Het |
| Itgb4 |
A |
G |
11: 115,896,561 (GRCm39) |
D1440G |
probably benign |
Het |
| Kdm3b |
A |
G |
18: 34,963,200 (GRCm39) |
D1552G |
probably damaging |
Het |
| Kel |
G |
A |
6: 41,663,418 (GRCm39) |
T702I |
possibly damaging |
Het |
| Klf3 |
T |
C |
5: 64,979,266 (GRCm39) |
V36A |
probably damaging |
Het |
| Klhl23 |
A |
T |
2: 69,659,228 (GRCm39) |
I418F |
probably damaging |
Het |
| Kndc1 |
A |
T |
7: 139,510,674 (GRCm39) |
I1329L |
probably benign |
Het |
| Krtap2-4 |
T |
C |
11: 99,505,606 (GRCm39) |
|
probably benign |
Het |
| Krtap9-5 |
T |
A |
11: 99,840,270 (GRCm39) |
C324S |
unknown |
Het |
| Lepr |
T |
C |
4: 101,630,178 (GRCm39) |
V631A |
possibly damaging |
Het |
| Lifr |
T |
C |
15: 7,216,404 (GRCm39) |
I793T |
probably damaging |
Het |
| Mcoln1 |
G |
A |
8: 3,561,731 (GRCm39) |
R427H |
probably damaging |
Het |
| Mgat5b |
G |
A |
11: 116,810,255 (GRCm39) |
|
probably benign |
Het |
| Mmp12 |
G |
A |
9: 7,349,802 (GRCm39) |
V78M |
probably damaging |
Het |
| Mrgprb8 |
T |
A |
7: 48,038,634 (GRCm39) |
L102M |
possibly damaging |
Het |
| Mybphl |
A |
G |
3: 108,282,949 (GRCm39) |
T246A |
possibly damaging |
Het |
| Myo7b |
A |
T |
18: 32,133,031 (GRCm39) |
F439L |
probably damaging |
Het |
| Myom1 |
A |
T |
17: 71,408,024 (GRCm39) |
D1088V |
probably damaging |
Het |
| Nrcam |
T |
C |
12: 44,623,471 (GRCm39) |
F1004S |
probably benign |
Het |
| Palld |
A |
T |
8: 61,986,467 (GRCm39) |
M788K |
possibly damaging |
Het |
| Pappa |
T |
A |
4: 65,234,465 (GRCm39) |
Y1423* |
probably null |
Het |
| Pfkm |
A |
G |
15: 98,027,171 (GRCm39) |
K615E |
probably damaging |
Het |
| Pkd1l2 |
G |
T |
8: 117,808,208 (GRCm39) |
D105E |
probably damaging |
Het |
| Plekha5 |
G |
A |
6: 140,518,603 (GRCm39) |
A297T |
probably damaging |
Het |
| Ppp6r2 |
A |
G |
15: 89,162,949 (GRCm39) |
T524A |
probably damaging |
Het |
| Psg26 |
T |
C |
7: 18,209,067 (GRCm39) |
E447G |
probably damaging |
Het |
| Rab3gap2 |
A |
G |
1: 185,014,586 (GRCm39) |
D1225G |
probably benign |
Het |
| Rep15 |
A |
G |
6: 146,934,403 (GRCm39) |
|
probably null |
Het |
| Rgl2 |
G |
A |
17: 34,152,314 (GRCm39) |
|
probably null |
Het |
| Rpl7a |
T |
G |
2: 26,801,473 (GRCm39) |
V55G |
possibly damaging |
Het |
| Rtp1 |
A |
T |
16: 23,250,108 (GRCm39) |
I158F |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,819,334 (GRCm39) |
V127E |
probably benign |
Het |
| Sele |
T |
A |
1: 163,881,395 (GRCm39) |
C501S |
probably damaging |
Het |
| Serpina11 |
C |
T |
12: 103,949,104 (GRCm39) |
V358I |
probably benign |
Het |
| Slc16a4 |
A |
G |
3: 107,211,819 (GRCm39) |
|
probably null |
Het |
| Slco6c1 |
T |
C |
1: 97,055,656 (GRCm39) |
I82V |
probably benign |
Het |
| Smarca5 |
T |
C |
8: 81,431,304 (GRCm39) |
E971G |
probably damaging |
Het |
| Smr2 |
T |
C |
5: 88,256,595 (GRCm39) |
L91P |
probably damaging |
Het |
| Spata31f3 |
T |
A |
4: 42,868,558 (GRCm39) |
H355L |
probably benign |
Het |
| Spopfm2 |
A |
T |
3: 94,082,973 (GRCm39) |
C279* |
probably null |
Het |
| Srrm2 |
A |
G |
17: 24,036,722 (GRCm39) |
|
probably benign |
Het |
| Sting1 |
A |
T |
18: 35,868,290 (GRCm39) |
M270K |
probably damaging |
Het |
| Syne1 |
A |
G |
10: 5,006,514 (GRCm39) |
W7980R |
probably damaging |
Het |
| Syne2 |
A |
G |
12: 76,074,853 (GRCm39) |
T4598A |
probably benign |
Het |
| Tmem171 |
A |
T |
13: 98,828,851 (GRCm39) |
F100I |
probably damaging |
Het |
| Tnfrsf10b |
A |
G |
14: 70,013,546 (GRCm39) |
T159A |
probably benign |
Het |
| Tph1 |
A |
T |
7: 46,309,834 (GRCm39) |
|
probably null |
Het |
| Trim46 |
A |
T |
3: 89,142,504 (GRCm39) |
I638N |
probably damaging |
Het |
| Ubl7 |
G |
A |
9: 57,827,825 (GRCm39) |
D171N |
probably damaging |
Het |
| Utp20 |
A |
G |
10: 88,608,779 (GRCm39) |
Y1514H |
probably damaging |
Het |
| Vmn2r81 |
A |
G |
10: 79,129,334 (GRCm39) |
I742V |
probably damaging |
Het |
| Xrcc2 |
A |
T |
5: 25,897,505 (GRCm39) |
V148E |
probably damaging |
Het |
| Zbed3 |
A |
G |
13: 95,472,615 (GRCm39) |
D13G |
possibly damaging |
Het |
| Zdhhc25 |
T |
A |
15: 88,484,962 (GRCm39) |
L99Q |
probably benign |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- TATGCTCGAGATATTCCCCGTTAC -3'
(R):5'- AGACCCCATTAGGTGACAGC -3'
Sequencing Primer
(F):5'- TTCCCCGTTACAAACAGATGGTG -3'
(R):5'- CCCATTAGGTGACAGCTATCAGATG -3'
|
| Posted On |
2014-09-18 |
Incidental Mutation