Incidental Mutation 'R1819:Tns1'
| ID |
204665 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tns1
|
| Ensembl Gene |
ENSMUSG00000055322 |
| Gene Name |
tensin 1 |
| Synonyms |
E030018G17Rik, 1110018I21Rik, E030037J05Rik, 1200014E20Rik, Tns |
| MMRRC Submission |
039847-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.565)
|
| Stock # |
R1819 (G1)
|
| Quality Score |
202 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
73949390-74163608 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
G to T
at 73955635 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148638
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000169786]
[ENSMUST00000187584]
[ENSMUST00000187691]
[ENSMUST00000191104]
[ENSMUST00000212888]
|
| AlphaFold |
E9Q0S6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169786
|
| SMART Domains |
Protein: ENSMUSP00000127715
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
1.77e-2 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
SCOP:d1d5ra2
|
176 |
348 |
3e-32 |
SMART |
|
PTEN_C2
|
350 |
477 |
1.12e-51 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1227 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1284 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1459 |
1470 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1530 |
N/A |
INTRINSIC |
|
SH2
|
1614 |
1716 |
6.85e-17 |
SMART |
|
PTB
|
1747 |
1888 |
1.69e-29 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000185331
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000185702
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187584
|
| SMART Domains |
Protein: ENSMUSP00000140254
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
21 |
67 |
8.6e-5 |
SMART |
|
low complexity region
|
113 |
124 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
197 |
319 |
9.9e-6 |
SMART |
|
PTEN_C2
|
306 |
433 |
5.6e-56 |
SMART |
|
low complexity region
|
778 |
789 |
N/A |
INTRINSIC |
|
low complexity region
|
861 |
878 |
N/A |
INTRINSIC |
|
low complexity region
|
1162 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1219 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1394 |
1405 |
N/A |
INTRINSIC |
|
low complexity region
|
1453 |
1465 |
N/A |
INTRINSIC |
|
SH2
|
1549 |
1651 |
4.3e-19 |
SMART |
|
PTB
|
1682 |
1823 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187691
|
| SMART Domains |
Protein: ENSMUSP00000139844
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
36 |
N/A |
INTRINSIC |
|
low complexity region
|
195 |
206 |
N/A |
INTRINSIC |
|
low complexity region
|
254 |
266 |
N/A |
INTRINSIC |
|
SH2
|
350 |
452 |
4.3e-19 |
SMART |
|
PTB
|
483 |
624 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191104
|
| SMART Domains |
Protein: ENSMUSP00000140317
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
8.6e-5 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
241 |
363 |
9.9e-6 |
SMART |
|
PTEN_C2
|
350 |
477 |
5.6e-56 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1218 |
N/A |
INTRINSIC |
|
low complexity region
|
1263 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1438 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1509 |
N/A |
INTRINSIC |
|
SH2
|
1593 |
1695 |
4.3e-19 |
SMART |
|
PTB
|
1726 |
1867 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212888
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.9%
|
| Validation Efficiency |
100% (91/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, and develop kidney cysts and progressive kidney degeneration that may lead to death from renal failure. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8b |
T |
C |
11: 109,871,882 (GRCm39) |
|
probably null |
Het |
| Abhd17a |
T |
C |
10: 80,422,470 (GRCm39) |
T71A |
probably benign |
Het |
| Acad11 |
G |
A |
9: 103,991,738 (GRCm39) |
|
probably null |
Het |
| Adgrf1 |
C |
A |
17: 43,620,924 (GRCm39) |
T387K |
probably benign |
Het |
| Afdn |
A |
G |
17: 14,071,110 (GRCm39) |
T783A |
probably damaging |
Het |
| Akap13 |
T |
A |
7: 75,258,453 (GRCm39) |
M359K |
probably benign |
Het |
| Asxl3 |
A |
T |
18: 22,655,433 (GRCm39) |
N1148Y |
probably damaging |
Het |
| Atl1 |
T |
C |
12: 70,010,074 (GRCm39) |
S547P |
probably benign |
Het |
| Bace1 |
A |
T |
9: 45,768,460 (GRCm39) |
T252S |
possibly damaging |
Het |
| BC034090 |
A |
G |
1: 155,101,575 (GRCm39) |
S230P |
possibly damaging |
Het |
| Bnc2 |
A |
G |
4: 84,210,111 (GRCm39) |
F778L |
possibly damaging |
Het |
| Capn2 |
T |
A |
1: 182,300,162 (GRCm39) |
K609N |
probably benign |
Het |
| Capn8 |
T |
A |
1: 182,426,391 (GRCm39) |
I242N |
probably damaging |
Het |
| Car9 |
G |
T |
4: 43,512,439 (GRCm39) |
|
probably null |
Het |
| Ccdc180 |
A |
G |
4: 45,926,195 (GRCm39) |
E1135G |
possibly damaging |
Het |
| Ccdc181 |
C |
T |
1: 164,110,047 (GRCm39) |
Q385* |
probably null |
Het |
| Cdh10 |
G |
T |
15: 18,992,051 (GRCm39) |
G437* |
probably null |
Het |
| Ceacam1 |
T |
A |
7: 25,163,285 (GRCm39) |
Q316L |
possibly damaging |
Het |
| Cecr2 |
A |
G |
6: 120,708,228 (GRCm39) |
T77A |
probably damaging |
Het |
| Cers4 |
T |
A |
8: 4,571,232 (GRCm39) |
M267K |
probably benign |
Het |
| Csmd3 |
T |
C |
15: 47,617,131 (GRCm39) |
D1930G |
possibly damaging |
Het |
| Cyp2j11 |
A |
T |
4: 96,185,976 (GRCm39) |
V403D |
probably damaging |
Het |
| Cyp4v3 |
G |
A |
8: 45,768,673 (GRCm39) |
R296C |
possibly damaging |
Het |
| Ddx59 |
A |
G |
1: 136,360,245 (GRCm39) |
I420V |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,246,546 (GRCm39) |
L628* |
probably null |
Het |
| Dnah7a |
A |
C |
1: 53,598,307 (GRCm39) |
D1409E |
probably benign |
Het |
| Dus2 |
T |
A |
8: 106,778,480 (GRCm39) |
W377R |
probably damaging |
Het |
| E330034G19Rik |
A |
G |
14: 24,348,081 (GRCm39) |
D111G |
probably damaging |
Het |
| Erich4 |
C |
T |
7: 25,314,715 (GRCm39) |
R66Q |
possibly damaging |
Het |
| Fcgbp |
G |
T |
7: 27,784,708 (GRCm39) |
R256L |
probably benign |
Het |
| Fdxr |
A |
T |
11: 115,166,930 (GRCm39) |
F53Y |
probably damaging |
Het |
| Fkbp10 |
G |
T |
11: 100,306,715 (GRCm39) |
A36S |
probably benign |
Het |
| Foxo3 |
A |
T |
10: 42,073,607 (GRCm39) |
D84E |
probably benign |
Het |
| Gin1 |
A |
G |
1: 97,712,951 (GRCm39) |
|
probably null |
Het |
| Gli3 |
C |
T |
13: 15,900,377 (GRCm39) |
Q1255* |
probably null |
Het |
| Gm4847 |
T |
A |
1: 166,465,788 (GRCm39) |
H267L |
probably damaging |
Het |
| Gpr171 |
T |
C |
3: 59,005,341 (GRCm39) |
I145V |
probably benign |
Het |
| Gpr68 |
T |
A |
12: 100,844,662 (GRCm39) |
H294L |
possibly damaging |
Het |
| Gys2 |
T |
C |
6: 142,406,912 (GRCm39) |
E148G |
probably damaging |
Het |
| Heatr5b |
T |
C |
17: 79,098,940 (GRCm39) |
D1320G |
probably damaging |
Het |
| Ifnlr1 |
G |
T |
4: 135,413,834 (GRCm39) |
|
probably benign |
Het |
| Ift88 |
G |
A |
14: 57,692,976 (GRCm39) |
E392K |
probably damaging |
Het |
| Igsf9b |
T |
A |
9: 27,222,889 (GRCm39) |
S97T |
probably damaging |
Het |
| Il18rap |
A |
G |
1: 40,570,687 (GRCm39) |
I210V |
probably benign |
Het |
| Kcnj11 |
C |
T |
7: 45,748,580 (GRCm39) |
G248S |
probably benign |
Het |
| Kif28 |
T |
C |
1: 179,533,319 (GRCm39) |
K541E |
possibly damaging |
Het |
| Lilrb4a |
A |
G |
10: 51,372,124 (GRCm39) |
Y205C |
probably damaging |
Het |
| Lima1 |
T |
A |
15: 99,717,817 (GRCm39) |
H63L |
probably benign |
Het |
| Lonrf3 |
A |
G |
X: 35,622,361 (GRCm39) |
I687V |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,449,941 (GRCm39) |
T2099A |
possibly damaging |
Het |
| Morn5 |
C |
T |
2: 35,942,987 (GRCm39) |
T29M |
probably damaging |
Het |
| Neurl1b |
G |
A |
17: 26,657,674 (GRCm39) |
R22H |
probably benign |
Het |
| Nr2e3 |
T |
C |
9: 59,850,720 (GRCm39) |
I380V |
probably damaging |
Het |
| Oas1c |
G |
A |
5: 120,946,800 (GRCm39) |
A10V |
possibly damaging |
Het |
| Or1e35 |
T |
C |
11: 73,797,505 (GRCm39) |
E271G |
probably benign |
Het |
| Or52e8 |
C |
T |
7: 104,624,605 (GRCm39) |
V196I |
probably benign |
Het |
| P3h3 |
T |
C |
6: 124,831,895 (GRCm39) |
T297A |
probably benign |
Het |
| Pdpk1 |
T |
C |
17: 24,329,878 (GRCm39) |
K53E |
probably damaging |
Het |
| Plec |
C |
T |
15: 76,064,106 (GRCm39) |
R2056Q |
probably damaging |
Het |
| Plxna2 |
T |
A |
1: 194,472,494 (GRCm39) |
N1079K |
probably benign |
Het |
| Prr12 |
G |
C |
7: 44,698,121 (GRCm39) |
|
probably benign |
Het |
| Psip1 |
A |
G |
4: 83,376,400 (GRCm39) |
S480P |
probably benign |
Het |
| Ptpre |
A |
G |
7: 135,270,722 (GRCm39) |
|
probably benign |
Het |
| Pvalb |
A |
C |
15: 78,086,784 (GRCm39) |
V44G |
probably damaging |
Het |
| Rab3c |
T |
G |
13: 110,220,669 (GRCm39) |
Q164P |
possibly damaging |
Het |
| Rubcn |
T |
C |
16: 32,647,284 (GRCm39) |
K703R |
possibly damaging |
Het |
| Setd7 |
T |
G |
3: 51,450,060 (GRCm39) |
H122P |
probably benign |
Het |
| Slc26a8 |
A |
T |
17: 28,903,808 (GRCm39) |
F19I |
probably benign |
Het |
| Slc6a14 |
A |
G |
X: 21,607,286 (GRCm39) |
D625G |
probably benign |
Het |
| Snx6 |
C |
T |
12: 54,830,259 (GRCm39) |
V67I |
possibly damaging |
Het |
| Syngr3 |
A |
G |
17: 24,906,696 (GRCm39) |
F40L |
possibly damaging |
Het |
| Syt8 |
G |
A |
7: 141,991,971 (GRCm39) |
G21R |
possibly damaging |
Het |
| Tagln |
A |
G |
9: 45,842,138 (GRCm39) |
F152L |
probably benign |
Het |
| Tcf12 |
G |
A |
9: 72,016,999 (GRCm39) |
T36M |
probably damaging |
Het |
| Tdrd6 |
C |
T |
17: 43,937,442 (GRCm39) |
S1202N |
probably benign |
Het |
| Tekt2 |
T |
C |
4: 126,217,529 (GRCm39) |
K179E |
probably damaging |
Het |
| Tekt4 |
G |
T |
17: 25,692,785 (GRCm39) |
|
probably null |
Het |
| Tmprss5 |
G |
T |
9: 49,018,464 (GRCm39) |
R98L |
probably benign |
Het |
| Tpcn1 |
A |
C |
5: 120,674,292 (GRCm39) |
|
probably null |
Het |
| Ttc6 |
T |
C |
12: 57,741,286 (GRCm39) |
|
probably null |
Het |
| Ttf1 |
A |
G |
2: 28,964,796 (GRCm39) |
N706S |
possibly damaging |
Het |
| Washc4 |
C |
T |
10: 83,386,748 (GRCm39) |
T124I |
probably benign |
Het |
| Wdr17 |
A |
T |
8: 55,143,159 (GRCm39) |
S140T |
probably benign |
Het |
| Wdr19 |
A |
T |
5: 65,370,234 (GRCm39) |
I123F |
possibly damaging |
Het |
| Zer1 |
C |
T |
2: 30,000,230 (GRCm39) |
A317T |
probably benign |
Het |
| Zfp474 |
A |
G |
18: 52,771,872 (GRCm39) |
D175G |
probably damaging |
Het |
| Zfp598 |
T |
C |
17: 24,900,104 (GRCm39) |
|
probably benign |
Het |
| Zfp646 |
G |
A |
7: 127,482,292 (GRCm39) |
G1490S |
probably benign |
Het |
| Zranb3 |
A |
T |
1: 127,945,293 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Tns1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00954:Tns1
|
APN |
1 |
73,964,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01288:Tns1
|
APN |
1 |
73,992,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01536:Tns1
|
APN |
1 |
73,958,807 (GRCm39) |
splice site |
probably benign |
|
|
IGL01568:Tns1
|
APN |
1 |
73,992,668 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01683:Tns1
|
APN |
1 |
73,992,428 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02267:Tns1
|
APN |
1 |
74,031,290 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02597:Tns1
|
APN |
1 |
74,025,032 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02819:Tns1
|
APN |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03370:Tns1
|
APN |
1 |
74,025,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0087:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0207:Tns1
|
UTSW |
1 |
73,976,477 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0411:Tns1
|
UTSW |
1 |
73,964,920 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0543:Tns1
|
UTSW |
1 |
73,991,856 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0552:Tns1
|
UTSW |
1 |
73,959,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0720:Tns1
|
UTSW |
1 |
73,964,740 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0828:Tns1
|
UTSW |
1 |
73,958,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1034:Tns1
|
UTSW |
1 |
73,981,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1061:Tns1
|
UTSW |
1 |
73,956,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1826:Tns1
|
UTSW |
1 |
73,992,793 (GRCm39) |
start codon destroyed |
probably null |
0.91 |
|
R2208:Tns1
|
UTSW |
1 |
74,118,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3723:Tns1
|
UTSW |
1 |
73,964,099 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4079:Tns1
|
UTSW |
1 |
74,034,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Tns1
|
UTSW |
1 |
73,981,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Tns1
|
UTSW |
1 |
73,953,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4274:Tns1
|
UTSW |
1 |
73,967,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4426:Tns1
|
UTSW |
1 |
74,024,908 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4649:Tns1
|
UTSW |
1 |
73,992,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4742:Tns1
|
UTSW |
1 |
74,163,449 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4869:Tns1
|
UTSW |
1 |
73,991,774 (GRCm39) |
missense |
probably benign |
|
|
R4961:Tns1
|
UTSW |
1 |
73,975,074 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5025:Tns1
|
UTSW |
1 |
73,964,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5035:Tns1
|
UTSW |
1 |
73,992,979 (GRCm39) |
start gained |
probably benign |
|
|
R5062:Tns1
|
UTSW |
1 |
73,992,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5080:Tns1
|
UTSW |
1 |
73,992,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5213:Tns1
|
UTSW |
1 |
73,992,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5256:Tns1
|
UTSW |
1 |
74,034,585 (GRCm39) |
intron |
probably benign |
|
|
R5368:Tns1
|
UTSW |
1 |
73,980,176 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5391:Tns1
|
UTSW |
1 |
74,029,568 (GRCm39) |
splice site |
probably null |
|
|
R5587:Tns1
|
UTSW |
1 |
73,959,755 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5735:Tns1
|
UTSW |
1 |
73,967,138 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Tns1
|
UTSW |
1 |
73,957,192 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5999:Tns1
|
UTSW |
1 |
73,967,256 (GRCm39) |
nonsense |
probably null |
|
|
R6122:Tns1
|
UTSW |
1 |
73,991,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6148:Tns1
|
UTSW |
1 |
73,992,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6457:Tns1
|
UTSW |
1 |
73,957,209 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6525:Tns1
|
UTSW |
1 |
73,992,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6712:Tns1
|
UTSW |
1 |
74,118,460 (GRCm39) |
nonsense |
probably null |
|
|
R6773:Tns1
|
UTSW |
1 |
73,958,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6825:Tns1
|
UTSW |
1 |
74,041,482 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Tns1
|
UTSW |
1 |
73,964,621 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7128:Tns1
|
UTSW |
1 |
74,034,463 (GRCm39) |
missense |
|
|
|
R7209:Tns1
|
UTSW |
1 |
73,993,074 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7348:Tns1
|
UTSW |
1 |
73,956,076 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7570:Tns1
|
UTSW |
1 |
73,992,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7670:Tns1
|
UTSW |
1 |
73,991,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7769:Tns1
|
UTSW |
1 |
73,992,530 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7833:Tns1
|
UTSW |
1 |
74,130,490 (GRCm39) |
intron |
probably benign |
|
|
R8052:Tns1
|
UTSW |
1 |
73,992,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8225:Tns1
|
UTSW |
1 |
74,025,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Tns1
|
UTSW |
1 |
73,976,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8321:Tns1
|
UTSW |
1 |
74,024,939 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8344:Tns1
|
UTSW |
1 |
74,024,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8378:Tns1
|
UTSW |
1 |
73,976,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8434:Tns1
|
UTSW |
1 |
73,964,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8773:Tns1
|
UTSW |
1 |
73,976,407 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9211:Tns1
|
UTSW |
1 |
73,956,948 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9251:Tns1
|
UTSW |
1 |
74,030,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9315:Tns1
|
UTSW |
1 |
73,980,141 (GRCm39) |
missense |
|
|
|
R9411:Tns1
|
UTSW |
1 |
73,992,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9592:Tns1
|
UTSW |
1 |
74,029,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9658:Tns1
|
UTSW |
1 |
73,981,183 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9658:Tns1
|
UTSW |
1 |
73,981,182 (GRCm39) |
missense |
probably benign |
0.14 |
|
Z1177:Tns1
|
UTSW |
1 |
74,041,466 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACGTCTTTGTTAGCATGAAGATG -3'
(R):5'- TGGTGACTTCCCACAGACTTC -3'
Sequencing Primer
(F):5'- TATTAGACCCCTGGCCTA -3'
(R):5'- GTGACTTCCCACAGACTTCATTGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation