Incidental Mutation 'R1800:Myo15b'
| ID |
203064 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo15b
|
| Ensembl Gene |
ENSMUSG00000034427 |
| Gene Name |
myosin XVB |
| Synonyms |
LOC217328, LOC380737, E330039G21Rik |
| MMRRC Submission |
039830-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.069)
|
| Stock # |
R1800 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
115749232-115783429 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (1 bp from exon) |
| DNA Base Change (assembly) |
G to T
at 115771335 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152405
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040703]
[ENSMUST00000093911]
[ENSMUST00000222123]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000040703
|
| SMART Domains |
Protein: ENSMUSP00000048072
Gene: ENSMUSG00000034427
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
93 |
111 |
N/A |
INTRINSIC |
|
low complexity region
|
179 |
213 |
N/A |
INTRINSIC |
|
low complexity region
|
250 |
289 |
N/A |
INTRINSIC |
|
low complexity region
|
345 |
370 |
N/A |
INTRINSIC |
|
low complexity region
|
497 |
511 |
N/A |
INTRINSIC |
|
low complexity region
|
532 |
552 |
N/A |
INTRINSIC |
|
Blast:MYSc
|
587 |
775 |
3e-15 |
BLAST |
|
SH3
|
778 |
835 |
1.15e-7 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000093911
|
| SMART Domains |
Protein: ENSMUSP00000091439
Gene: ENSMUSG00000034427
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
1 |
640 |
2.4e-134 |
SMART |
|
IQ
|
660 |
682 |
1.03e1 |
SMART |
|
Pfam:MyTH4
|
837 |
945 |
2.1e-23 |
PFAM |
|
low complexity region
|
1050 |
1068 |
N/A |
INTRINSIC |
|
low complexity region
|
1136 |
1170 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1302 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1468 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1509 |
N/A |
INTRINSIC |
|
SH3
|
1735 |
1792 |
1.15e-7 |
SMART |
|
Pfam:MyTH4
|
1928 |
2029 |
8.3e-25 |
PFAM |
|
B41
|
2032 |
2235 |
6.99e-4 |
SMART |
|
low complexity region
|
2243 |
2253 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151507
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000222123
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.0%
- 20x: 91.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,772,479 (GRCm39) |
K556R |
probably damaging |
Het |
| 4933406P04Rik |
A |
T |
10: 20,186,893 (GRCm39) |
|
probably benign |
Het |
| Acmsd |
C |
A |
1: 127,687,493 (GRCm39) |
Y258* |
probably null |
Het |
| Adgrf5 |
A |
T |
17: 43,761,973 (GRCm39) |
I1223F |
probably damaging |
Het |
| Afp |
C |
T |
5: 90,638,655 (GRCm39) |
P6S |
probably benign |
Het |
| Agap2 |
C |
A |
10: 126,927,540 (GRCm39) |
H1120Q |
probably damaging |
Het |
| Angpt1 |
A |
G |
15: 42,375,800 (GRCm39) |
V152A |
probably damaging |
Het |
| Ankrd1 |
A |
T |
19: 36,096,759 (GRCm39) |
F23I |
probably damaging |
Het |
| Armc12 |
T |
C |
17: 28,757,869 (GRCm39) |
S334P |
possibly damaging |
Het |
| Arnt2 |
C |
A |
7: 83,924,583 (GRCm39) |
D415Y |
probably damaging |
Het |
| Cacna1s |
G |
T |
1: 136,004,592 (GRCm39) |
V131L |
probably benign |
Het |
| Cacna2d2 |
T |
C |
9: 107,404,632 (GRCm39) |
V1141A |
possibly damaging |
Het |
| Cfap61 |
T |
C |
2: 145,884,542 (GRCm39) |
L580P |
probably damaging |
Het |
| Chga |
A |
T |
12: 102,522,164 (GRCm39) |
S23C |
probably damaging |
Het |
| Chrna5 |
A |
G |
9: 54,912,159 (GRCm39) |
T320A |
probably damaging |
Het |
| Col17a1 |
G |
T |
19: 47,639,301 (GRCm39) |
N1081K |
possibly damaging |
Het |
| Cox7b2 |
A |
T |
5: 71,600,406 (GRCm39) |
C51S |
possibly damaging |
Het |
| Cstdc3 |
T |
A |
16: 36,132,895 (GRCm39) |
D57E |
probably damaging |
Het |
| Cwc22 |
A |
T |
2: 77,759,797 (GRCm39) |
D83E |
possibly damaging |
Het |
| D130043K22Rik |
A |
C |
13: 25,067,877 (GRCm39) |
D871A |
probably damaging |
Het |
| Dab2 |
A |
T |
15: 6,464,948 (GRCm39) |
M361L |
probably benign |
Het |
| Dnah11 |
A |
C |
12: 117,880,523 (GRCm39) |
Y3866D |
probably damaging |
Het |
| Dnmbp |
A |
G |
19: 43,890,159 (GRCm39) |
I536T |
probably benign |
Het |
| Ehmt1 |
A |
T |
2: 24,774,302 (GRCm39) |
S43R |
probably damaging |
Het |
| Ercc5 |
T |
C |
1: 44,212,540 (GRCm39) |
L666P |
probably benign |
Het |
| F5 |
A |
G |
1: 164,010,403 (GRCm39) |
H378R |
probably damaging |
Het |
| Fat2 |
A |
T |
11: 55,174,718 (GRCm39) |
N1998K |
probably damaging |
Het |
| Fbxo28 |
T |
C |
1: 182,169,099 (GRCm39) |
D13G |
unknown |
Het |
| Fras1 |
T |
C |
5: 96,857,741 (GRCm39) |
S2012P |
probably benign |
Het |
| Gm5624 |
T |
A |
14: 44,799,302 (GRCm39) |
N41I |
probably damaging |
Het |
| Gm8104 |
A |
G |
14: 42,959,028 (GRCm39) |
I73V |
possibly damaging |
Het |
| Gpr141b |
T |
C |
13: 19,913,849 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr68 |
G |
A |
12: 100,845,167 (GRCm39) |
P126S |
probably damaging |
Het |
| Gucy1a2 |
A |
T |
9: 3,582,685 (GRCm39) |
T156S |
possibly damaging |
Het |
| Hacl1 |
T |
A |
14: 31,336,221 (GRCm39) |
Y429F |
probably damaging |
Het |
| Haus3 |
A |
C |
5: 34,320,916 (GRCm39) |
L510R |
probably damaging |
Het |
| Helq |
C |
T |
5: 100,921,990 (GRCm39) |
G738D |
probably benign |
Het |
| Hsd3b2 |
G |
C |
3: 98,619,553 (GRCm39) |
P131A |
probably damaging |
Het |
| Il22ra1 |
G |
T |
4: 135,475,471 (GRCm39) |
C247F |
probably benign |
Het |
| Ivl |
T |
C |
3: 92,479,891 (GRCm39) |
E58G |
unknown |
Het |
| Kcnk9 |
G |
T |
15: 72,417,948 (GRCm39) |
Q61K |
probably benign |
Het |
| Kremen1 |
CGGG |
CGGGGGG |
11: 5,151,791 (GRCm39) |
|
probably benign |
Het |
| Loxhd1 |
G |
T |
18: 77,490,198 (GRCm39) |
A1314S |
probably damaging |
Het |
| Lratd1 |
T |
C |
12: 14,200,226 (GRCm39) |
Y167C |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,259,175 (GRCm39) |
I1397V |
probably benign |
Het |
| Lrig3 |
T |
A |
10: 125,832,920 (GRCm39) |
|
probably null |
Het |
| Lrrc36 |
A |
G |
8: 106,176,397 (GRCm39) |
D378G |
probably damaging |
Het |
| Lrrc49 |
G |
A |
9: 60,505,474 (GRCm39) |
T527I |
probably damaging |
Het |
| Map4k4 |
C |
A |
1: 40,062,620 (GRCm39) |
T1195K |
probably damaging |
Het |
| Mrps33 |
G |
A |
6: 39,779,429 (GRCm39) |
R89C |
probably damaging |
Het |
| Mtor |
T |
C |
4: 148,547,349 (GRCm39) |
V444A |
probably benign |
Het |
| Myh2 |
A |
G |
11: 67,079,764 (GRCm39) |
E1046G |
probably damaging |
Het |
| Myo5c |
T |
C |
9: 75,153,446 (GRCm39) |
Y111H |
probably damaging |
Het |
| Ncoa4-ps |
A |
T |
12: 119,225,506 (GRCm39) |
|
noncoding transcript |
Het |
| Ndufv2 |
G |
C |
17: 66,390,481 (GRCm39) |
T163R |
probably damaging |
Het |
| Nf1 |
A |
G |
11: 79,444,794 (GRCm39) |
N373S |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,962,917 (GRCm39) |
M834V |
probably benign |
Het |
| Ogfod2 |
T |
C |
5: 124,253,019 (GRCm39) |
V343A |
probably damaging |
Het |
| Or11g2 |
C |
T |
14: 50,856,143 (GRCm39) |
L155F |
probably benign |
Het |
| Or11j4 |
C |
A |
14: 50,630,786 (GRCm39) |
S191* |
probably null |
Het |
| Or3a1b |
A |
T |
11: 74,012,234 (GRCm39) |
T40S |
probably benign |
Het |
| Or4c115 |
T |
A |
2: 88,928,050 (GRCm39) |
T74S |
probably benign |
Het |
| Or51ag1 |
T |
C |
7: 103,155,248 (GRCm39) |
I302V |
possibly damaging |
Het |
| Or52ab2 |
T |
A |
7: 102,969,621 (GRCm39) |
M1K |
probably null |
Het |
| Or8g34 |
A |
T |
9: 39,373,410 (GRCm39) |
I228F |
probably damaging |
Het |
| Parp1 |
T |
A |
1: 180,428,091 (GRCm39) |
|
probably null |
Het |
| Ppp3ca |
A |
T |
3: 136,640,792 (GRCm39) |
I448F |
probably damaging |
Het |
| Prss44 |
T |
C |
9: 110,646,272 (GRCm39) |
V333A |
probably damaging |
Het |
| Pxk |
C |
T |
14: 8,151,507 (GRCm38) |
R441* |
probably null |
Het |
| Rars1 |
A |
C |
11: 35,716,822 (GRCm39) |
D231E |
probably benign |
Het |
| Rfc1 |
T |
C |
5: 65,421,722 (GRCm39) |
Y1059C |
probably damaging |
Het |
| Rilpl1 |
T |
A |
5: 124,652,719 (GRCm39) |
I2F |
probably damaging |
Het |
| Sarm1 |
G |
T |
11: 78,381,820 (GRCm39) |
A221E |
possibly damaging |
Het |
| Serpina3f |
A |
G |
12: 104,183,665 (GRCm39) |
T176A |
probably damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,035,695 (GRCm39) |
E131G |
probably benign |
Het |
| Slc26a11 |
T |
C |
11: 119,263,979 (GRCm39) |
V343A |
probably damaging |
Het |
| Slc2a4 |
A |
G |
11: 69,837,133 (GRCm39) |
I9T |
probably benign |
Het |
| Slc39a6 |
G |
T |
18: 24,718,259 (GRCm39) |
D599E |
probably damaging |
Het |
| Slc5a6 |
G |
T |
5: 31,198,020 (GRCm39) |
S285* |
probably null |
Het |
| Spata9 |
A |
G |
13: 76,125,760 (GRCm39) |
H81R |
probably benign |
Het |
| St7l |
A |
G |
3: 104,826,812 (GRCm39) |
E436G |
probably damaging |
Het |
| Tecrl |
A |
G |
5: 83,427,077 (GRCm39) |
I357T |
probably damaging |
Het |
| Thop1 |
C |
T |
10: 80,909,043 (GRCm39) |
R25C |
probably damaging |
Het |
| Tmprss12 |
A |
G |
15: 100,190,428 (GRCm39) |
E266G |
probably benign |
Het |
| Tpgs1 |
T |
A |
10: 79,511,344 (GRCm39) |
V162D |
possibly damaging |
Het |
| Trpa1 |
C |
T |
1: 14,944,648 (GRCm39) |
R1032Q |
probably benign |
Het |
| Tspan12 |
A |
G |
6: 21,795,699 (GRCm39) |
Y164H |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,135,274 (GRCm39) |
Y869H |
probably damaging |
Het |
| Vmn1r21 |
A |
G |
6: 57,820,799 (GRCm39) |
I215T |
probably benign |
Het |
| Zan |
A |
T |
5: 137,384,713 (GRCm39) |
S5104T |
unknown |
Het |
| Zfp318 |
T |
C |
17: 46,722,980 (GRCm39) |
V1661A |
probably benign |
Het |
| Zfp365 |
C |
T |
10: 67,724,772 (GRCm39) |
R372K |
probably damaging |
Het |
|
| Other mutations in Myo15b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Myo15b
|
APN |
11 |
115,782,742 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01409:Myo15b
|
APN |
11 |
115,760,330 (GRCm39) |
nonsense |
probably null |
|
|
IGL01539:Myo15b
|
APN |
11 |
115,754,299 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01895:Myo15b
|
APN |
11 |
115,774,324 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02254:Myo15b
|
APN |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02343:Myo15b
|
APN |
11 |
115,764,226 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02349:Myo15b
|
APN |
11 |
115,753,931 (GRCm39) |
splice site |
probably benign |
|
|
IGL02368:Myo15b
|
APN |
11 |
115,767,828 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02576:Myo15b
|
APN |
11 |
115,780,879 (GRCm39) |
missense |
probably null |
0.97 |
|
IGL02650:Myo15b
|
APN |
11 |
115,777,337 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02661:Myo15b
|
APN |
11 |
115,774,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02716:Myo15b
|
APN |
11 |
115,774,535 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02733:Myo15b
|
APN |
11 |
115,775,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02951:Myo15b
|
APN |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03017:Myo15b
|
APN |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03029:Myo15b
|
APN |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
ANU74:Myo15b
|
UTSW |
11 |
115,769,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0092:Myo15b
|
UTSW |
11 |
115,753,812 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0255:Myo15b
|
UTSW |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0325:Myo15b
|
UTSW |
11 |
115,775,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Myo15b
|
UTSW |
11 |
115,773,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Myo15b
|
UTSW |
11 |
115,755,468 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0711:Myo15b
|
UTSW |
11 |
115,774,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0815:Myo15b
|
UTSW |
11 |
115,757,162 (GRCm39) |
splice site |
probably benign |
|
|
R0961:Myo15b
|
UTSW |
11 |
115,773,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1066:Myo15b
|
UTSW |
11 |
115,770,577 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1221:Myo15b
|
UTSW |
11 |
115,777,546 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1240:Myo15b
|
UTSW |
11 |
115,771,327 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1275:Myo15b
|
UTSW |
11 |
115,774,318 (GRCm39) |
small deletion |
probably benign |
|
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1317:Myo15b
|
UTSW |
11 |
115,774,460 (GRCm39) |
missense |
probably null |
0.14 |
|
R1491:Myo15b
|
UTSW |
11 |
115,777,683 (GRCm39) |
splice site |
probably null |
|
|
R1552:Myo15b
|
UTSW |
11 |
115,757,461 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1731:Myo15b
|
UTSW |
11 |
115,782,386 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1843:Myo15b
|
UTSW |
11 |
115,760,412 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Myo15b
|
UTSW |
11 |
115,773,080 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1934:Myo15b
|
UTSW |
11 |
115,754,310 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1939:Myo15b
|
UTSW |
11 |
115,778,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1945:Myo15b
|
UTSW |
11 |
115,769,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Myo15b
|
UTSW |
11 |
115,773,701 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2130:Myo15b
|
UTSW |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2138:Myo15b
|
UTSW |
11 |
115,774,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2176:Myo15b
|
UTSW |
11 |
115,757,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Myo15b
|
UTSW |
11 |
115,770,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Myo15b
|
UTSW |
11 |
115,755,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3620:Myo15b
|
UTSW |
11 |
115,762,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3716:Myo15b
|
UTSW |
11 |
115,754,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4013:Myo15b
|
UTSW |
11 |
115,762,282 (GRCm39) |
nonsense |
probably null |
|
|
R4021:Myo15b
|
UTSW |
11 |
115,764,331 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4119:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4120:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4499:Myo15b
|
UTSW |
11 |
115,781,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4653:Myo15b
|
UTSW |
11 |
115,770,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4655:Myo15b
|
UTSW |
11 |
115,781,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Myo15b
|
UTSW |
11 |
115,752,761 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4702:Myo15b
|
UTSW |
11 |
115,774,834 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4777:Myo15b
|
UTSW |
11 |
115,770,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4833:Myo15b
|
UTSW |
11 |
115,778,428 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5083:Myo15b
|
UTSW |
11 |
115,757,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5121:Myo15b
|
UTSW |
11 |
115,776,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5146:Myo15b
|
UTSW |
11 |
115,782,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5535:Myo15b
|
UTSW |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5647:Myo15b
|
UTSW |
11 |
115,762,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5849:Myo15b
|
UTSW |
11 |
115,772,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5882:Myo15b
|
UTSW |
11 |
115,760,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5956:Myo15b
|
UTSW |
11 |
115,764,583 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6273:Myo15b
|
UTSW |
11 |
115,753,625 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6302:Myo15b
|
UTSW |
11 |
115,777,065 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6318:Myo15b
|
UTSW |
11 |
115,781,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6462:Myo15b
|
UTSW |
11 |
115,750,268 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6792:Myo15b
|
UTSW |
11 |
115,775,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo15b
|
UTSW |
11 |
115,781,540 (GRCm39) |
splice site |
probably null |
|
|
R7015:Myo15b
|
UTSW |
11 |
115,762,670 (GRCm39) |
missense |
|
|
|
R7020:Myo15b
|
UTSW |
11 |
115,757,493 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Myo15b
|
UTSW |
11 |
115,782,324 (GRCm39) |
splice site |
probably null |
|
|
R7219:Myo15b
|
UTSW |
11 |
115,767,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7400:Myo15b
|
UTSW |
11 |
115,750,939 (GRCm39) |
missense |
|
|
|
R7413:Myo15b
|
UTSW |
11 |
115,768,970 (GRCm39) |
missense |
|
|
|
R7483:Myo15b
|
UTSW |
11 |
115,749,570 (GRCm39) |
missense |
|
|
|
R7523:Myo15b
|
UTSW |
11 |
115,781,684 (GRCm39) |
missense |
unknown |
|
|
R7737:Myo15b
|
UTSW |
11 |
115,778,749 (GRCm39) |
missense |
unknown |
|
|
R7784:Myo15b
|
UTSW |
11 |
115,752,166 (GRCm39) |
missense |
|
|
|
R7842:Myo15b
|
UTSW |
11 |
115,762,321 (GRCm39) |
missense |
|
|
|
R7921:Myo15b
|
UTSW |
11 |
115,778,004 (GRCm39) |
nonsense |
probably null |
|
|
R8065:Myo15b
|
UTSW |
11 |
115,778,769 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8183:Myo15b
|
UTSW |
11 |
115,773,843 (GRCm39) |
splice site |
probably null |
|
|
R8193:Myo15b
|
UTSW |
11 |
115,775,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Myo15b
|
UTSW |
11 |
115,767,827 (GRCm39) |
missense |
|
|
|
R8430:Myo15b
|
UTSW |
11 |
115,773,049 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8482:Myo15b
|
UTSW |
11 |
115,774,083 (GRCm39) |
nonsense |
probably null |
|
|
R8515:Myo15b
|
UTSW |
11 |
115,749,610 (GRCm39) |
missense |
|
|
|
R8798:Myo15b
|
UTSW |
11 |
115,754,232 (GRCm39) |
missense |
|
|
|
R8937:Myo15b
|
UTSW |
11 |
115,773,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8975:Myo15b
|
UTSW |
11 |
115,781,780 (GRCm39) |
missense |
unknown |
|
|
R9045:Myo15b
|
UTSW |
11 |
115,783,178 (GRCm39) |
makesense |
probably null |
|
|
R9117:Myo15b
|
UTSW |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9185:Myo15b
|
UTSW |
11 |
115,771,255 (GRCm39) |
missense |
unknown |
|
|
R9226:Myo15b
|
UTSW |
11 |
115,750,924 (GRCm39) |
missense |
|
|
|
R9302:Myo15b
|
UTSW |
11 |
115,776,238 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9318:Myo15b
|
UTSW |
11 |
115,775,965 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9336:Myo15b
|
UTSW |
11 |
115,771,064 (GRCm39) |
missense |
|
|
|
R9337:Myo15b
|
UTSW |
11 |
115,749,861 (GRCm39) |
missense |
|
|
|
R9338:Myo15b
|
UTSW |
11 |
115,762,238 (GRCm39) |
missense |
|
|
|
R9498:Myo15b
|
UTSW |
11 |
115,770,784 (GRCm39) |
missense |
|
|
|
R9500:Myo15b
|
UTSW |
11 |
115,777,466 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9602:Myo15b
|
UTSW |
11 |
115,769,269 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9642:Myo15b
|
UTSW |
11 |
115,772,335 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0020:Myo15b
|
UTSW |
11 |
115,762,625 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,778,751 (GRCm39) |
missense |
unknown |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,774,278 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCCTGAGATCCTCATGTC -3'
(R):5'- TGCCCGTCATTTAGAATCTCTG -3'
Sequencing Primer
(F):5'- AGATCCTCATGTCCTAGGTCTGG -3'
(R):5'- ATGCAGTAGAGCAGCAGT -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation