Incidental Mutation 'R1538:Kirrel1'
| ID |
169661 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
039577-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1538 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 86996458 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 380
(M380I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041732
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107618
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159976
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0922 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.1%
- 10x: 95.5%
- 20x: 89.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
G |
T |
3: 137,771,162 (GRCm39) |
R117L |
probably benign |
Het |
| 4930447C04Rik |
G |
A |
12: 72,928,120 (GRCm39) |
A537V |
possibly damaging |
Het |
| 4930579F01Rik |
A |
C |
3: 137,889,517 (GRCm39) |
D33E |
probably damaging |
Het |
| Acnat1 |
T |
C |
4: 49,447,835 (GRCm39) |
K249E |
possibly damaging |
Het |
| Ankrd13a |
T |
C |
5: 114,942,295 (GRCm39) |
I526T |
possibly damaging |
Het |
| Aplp1 |
C |
A |
7: 30,135,452 (GRCm39) |
E535D |
probably benign |
Het |
| Armc8 |
T |
A |
9: 99,387,343 (GRCm39) |
H425L |
probably damaging |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| Asprv1 |
C |
T |
6: 86,605,618 (GRCm39) |
Q155* |
probably null |
Het |
| Atl1 |
A |
G |
12: 69,972,962 (GRCm39) |
Q94R |
probably benign |
Het |
| Atp2a2 |
A |
G |
5: 122,595,440 (GRCm39) |
L970P |
probably damaging |
Het |
| Atp8a2 |
T |
C |
14: 60,097,719 (GRCm39) |
K770E |
probably benign |
Het |
| Bod1l |
A |
G |
5: 41,973,772 (GRCm39) |
M2514T |
probably benign |
Het |
| Cacfd1 |
T |
A |
2: 26,908,951 (GRCm39) |
D97E |
probably benign |
Het |
| Cacna1e |
A |
G |
1: 154,437,504 (GRCm39) |
L344P |
probably damaging |
Het |
| Cacna2d2 |
C |
A |
9: 107,394,615 (GRCm39) |
R596S |
probably damaging |
Het |
| Catip |
C |
A |
1: 74,403,811 (GRCm39) |
S176* |
probably null |
Het |
| Cdcp1 |
G |
A |
9: 123,002,653 (GRCm39) |
S806L |
probably damaging |
Het |
| Cdk6 |
A |
T |
5: 3,570,675 (GRCm39) |
I289L |
probably benign |
Het |
| Cers3 |
C |
T |
7: 66,431,571 (GRCm39) |
T182I |
probably damaging |
Het |
| Cfap46 |
T |
A |
7: 139,262,924 (GRCm39) |
N43I |
probably null |
Het |
| Clec4n |
A |
T |
6: 123,206,992 (GRCm39) |
R5S |
possibly damaging |
Het |
| Cnr2 |
G |
T |
4: 135,644,012 (GRCm39) |
S30I |
probably benign |
Het |
| Col18a1 |
C |
T |
10: 76,907,170 (GRCm39) |
G870E |
probably damaging |
Het |
| Cpne6 |
T |
C |
14: 55,752,677 (GRCm39) |
V289A |
possibly damaging |
Het |
| Crym |
G |
A |
7: 119,796,938 (GRCm39) |
L141F |
probably benign |
Het |
| Cxxc5 |
T |
C |
18: 35,991,622 (GRCm39) |
S8P |
unknown |
Het |
| Dido1 |
A |
C |
2: 180,326,763 (GRCm39) |
S453R |
possibly damaging |
Het |
| Dnah2 |
A |
C |
11: 69,368,028 (GRCm39) |
S1770R |
probably benign |
Het |
| Dnah7a |
A |
G |
1: 53,535,148 (GRCm39) |
V2704A |
possibly damaging |
Het |
| Eml5 |
T |
C |
12: 98,760,535 (GRCm39) |
N1738S |
probably damaging |
Het |
| Eri3 |
A |
G |
4: 117,439,836 (GRCm39) |
T138A |
possibly damaging |
Het |
| Ext2 |
C |
T |
2: 93,537,632 (GRCm39) |
E585K |
probably damaging |
Het |
| Fbxw19 |
T |
A |
9: 109,324,056 (GRCm39) |
S38C |
probably damaging |
Het |
| Fcgbpl1 |
A |
T |
7: 27,854,917 (GRCm39) |
I1848F |
probably damaging |
Het |
| Fmo6 |
G |
A |
1: 162,753,675 (GRCm39) |
P156S |
probably damaging |
Het |
| Frem3 |
A |
T |
8: 81,339,764 (GRCm39) |
I686F |
probably benign |
Het |
| Frem3 |
T |
C |
8: 81,339,339 (GRCm39) |
L544P |
probably damaging |
Het |
| Gabra1 |
T |
C |
11: 42,031,177 (GRCm39) |
Y251C |
probably benign |
Het |
| Gemin4 |
G |
T |
11: 76,101,987 (GRCm39) |
Q925K |
probably benign |
Het |
| Gm18856 |
T |
A |
13: 14,139,274 (GRCm39) |
|
probably benign |
Het |
| Gnb1 |
A |
T |
4: 155,636,171 (GRCm39) |
T164S |
probably benign |
Het |
| Gpx6 |
A |
G |
13: 21,497,822 (GRCm39) |
D31G |
possibly damaging |
Het |
| Gzmd |
A |
C |
14: 56,367,802 (GRCm39) |
I157S |
probably benign |
Het |
| Il31ra |
T |
A |
13: 112,684,000 (GRCm39) |
N43I |
possibly damaging |
Het |
| Irak3 |
T |
C |
10: 120,001,035 (GRCm39) |
T297A |
probably benign |
Het |
| Kank2 |
T |
C |
9: 21,685,927 (GRCm39) |
D649G |
probably damaging |
Het |
| Kif3b |
AGAGGAGGAGGAGGAGG |
AGAGGAGGAGGAGG |
2: 153,159,382 (GRCm39) |
|
probably benign |
Het |
| Klhl18 |
A |
G |
9: 110,275,815 (GRCm39) |
F111S |
probably damaging |
Het |
| Lratd2 |
A |
G |
15: 60,695,498 (GRCm39) |
C83R |
probably damaging |
Het |
| Lrp5 |
A |
G |
19: 3,697,585 (GRCm39) |
S319P |
possibly damaging |
Het |
| Mettl15 |
T |
C |
2: 108,962,010 (GRCm39) |
|
probably null |
Het |
| Mtarc1 |
T |
C |
1: 184,534,199 (GRCm39) |
E223G |
probably damaging |
Het |
| Ncoa1 |
T |
C |
12: 4,320,748 (GRCm39) |
Q1107R |
possibly damaging |
Het |
| Ncoa7 |
T |
G |
10: 30,570,207 (GRCm39) |
M251L |
probably damaging |
Het |
| Nos2 |
A |
T |
11: 78,847,396 (GRCm39) |
M1023L |
probably benign |
Het |
| Nup107 |
T |
C |
10: 117,626,399 (GRCm39) |
K25E |
probably damaging |
Het |
| Or10q1b |
A |
T |
19: 13,682,860 (GRCm39) |
Y223F |
probably damaging |
Het |
| Or52s1b |
A |
G |
7: 102,822,193 (GRCm39) |
I217T |
probably damaging |
Het |
| Or5k14 |
T |
A |
16: 58,693,261 (GRCm39) |
N84I |
probably damaging |
Het |
| Or5p58 |
T |
A |
7: 107,694,493 (GRCm39) |
I95F |
probably damaging |
Het |
| Or6b6 |
A |
T |
7: 106,571,190 (GRCm39) |
Y120* |
probably null |
Het |
| Or6c206 |
T |
C |
10: 129,097,082 (GRCm39) |
I84T |
probably damaging |
Het |
| Parm1 |
G |
A |
5: 91,742,306 (GRCm39) |
E225K |
possibly damaging |
Het |
| Pdzd2 |
A |
C |
15: 12,373,047 (GRCm39) |
S2363A |
probably damaging |
Het |
| Piezo1 |
A |
G |
8: 123,218,142 (GRCm39) |
L1199P |
probably damaging |
Het |
| Prpsap1 |
A |
T |
11: 116,370,534 (GRCm39) |
M141K |
probably benign |
Het |
| Prss29 |
A |
T |
17: 25,539,257 (GRCm39) |
M1L |
possibly damaging |
Het |
| Pter |
T |
A |
2: 12,983,417 (GRCm39) |
S141T |
probably benign |
Het |
| Ptpru |
A |
T |
4: 131,501,662 (GRCm39) |
D1181E |
probably damaging |
Het |
| Rab3ip |
T |
A |
10: 116,775,159 (GRCm39) |
Q66H |
probably damaging |
Het |
| Rgs12 |
A |
T |
5: 35,178,511 (GRCm39) |
T779S |
probably damaging |
Het |
| Rgs22 |
A |
G |
15: 36,048,922 (GRCm39) |
F786S |
probably damaging |
Het |
| Rnasel |
A |
T |
1: 153,636,540 (GRCm39) |
D640V |
possibly damaging |
Het |
| Rp1 |
T |
C |
1: 4,415,899 (GRCm39) |
T1738A |
probably damaging |
Het |
| Sacs |
T |
C |
14: 61,447,508 (GRCm39) |
S3185P |
probably damaging |
Het |
| Scnn1a |
T |
A |
6: 125,315,856 (GRCm39) |
D321E |
possibly damaging |
Het |
| Sec31b |
G |
C |
19: 44,507,025 (GRCm39) |
L1014V |
probably benign |
Het |
| Serpinb10 |
A |
G |
1: 107,468,690 (GRCm39) |
Y111C |
probably damaging |
Het |
| Shld2 |
C |
G |
14: 33,990,833 (GRCm39) |
Q24H |
probably damaging |
Het |
| Siglecg |
A |
G |
7: 43,067,313 (GRCm39) |
K627E |
possibly damaging |
Het |
| Sigmar1 |
T |
C |
4: 41,740,845 (GRCm39) |
I95V |
probably benign |
Het |
| Sirpb1b |
T |
A |
3: 15,613,819 (GRCm39) |
T88S |
possibly damaging |
Het |
| Spire2 |
T |
G |
8: 124,084,895 (GRCm39) |
L245R |
probably damaging |
Het |
| Stard9 |
C |
A |
2: 120,527,192 (GRCm39) |
P1150T |
probably benign |
Het |
| Stat6 |
C |
A |
10: 127,489,125 (GRCm39) |
T380N |
probably damaging |
Het |
| Sult3a1 |
G |
A |
10: 33,746,166 (GRCm39) |
G162E |
probably benign |
Het |
| Surf4 |
T |
C |
2: 26,823,710 (GRCm39) |
|
probably null |
Het |
| Tacc2 |
T |
C |
7: 130,227,149 (GRCm39) |
M1278T |
probably benign |
Het |
| Tacr2 |
T |
A |
10: 62,097,106 (GRCm39) |
|
probably null |
Het |
| Tcaf1 |
A |
T |
6: 42,655,923 (GRCm39) |
V351E |
probably damaging |
Het |
| Tmcc2 |
A |
G |
1: 132,308,718 (GRCm39) |
S59P |
probably damaging |
Het |
| Tmem17 |
G |
A |
11: 22,467,266 (GRCm39) |
S60N |
possibly damaging |
Het |
| Tmem63b |
C |
G |
17: 45,989,904 (GRCm39) |
R88P |
possibly damaging |
Het |
| Tmprss7 |
A |
T |
16: 45,499,753 (GRCm39) |
I307N |
probably benign |
Het |
| Treml2 |
A |
T |
17: 48,609,786 (GRCm39) |
T73S |
possibly damaging |
Het |
| Trrap |
A |
G |
5: 144,774,012 (GRCm39) |
H2876R |
possibly damaging |
Het |
| Tyw3 |
A |
G |
3: 154,302,506 (GRCm39) |
I53T |
probably damaging |
Het |
| Ugp2 |
A |
G |
11: 21,283,791 (GRCm39) |
I92T |
possibly damaging |
Het |
| Vmn2r66 |
A |
T |
7: 84,644,166 (GRCm39) |
M748K |
possibly damaging |
Het |
| Vmn2r82 |
T |
C |
10: 79,192,578 (GRCm39) |
S52P |
possibly damaging |
Het |
| Wdr37 |
A |
T |
13: 8,886,828 (GRCm39) |
S320T |
probably benign |
Het |
| Zbtb16 |
A |
T |
9: 48,743,583 (GRCm39) |
M243K |
probably benign |
Het |
| Zfr |
C |
T |
15: 12,150,329 (GRCm39) |
T432I |
possibly damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTATGGCTGACTGCAAGTACCCTC -3'
(R):5'- GGGACGAAAACTCCACTAACCTGG -3'
Sequencing Primer
(F):5'- GACTGCAAGTACCCTCTTTCC -3'
(R):5'- AGCTGATGATTCTCAGGCAC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation