Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01819:Iqcf5'

154483

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Iqcf5

Ensembl Gene

ENSMUSG00000066382

Gene Name

IQ motif containing F5

Synonyms

1700007L12Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.054) question?

Stock #

IGL01819

Quality Score

Status

Chromosome

Chromosomal Location

106391772-106393202 bp(+) (GRCm39)

Type of Mutation

makesense

DNA Base Change (assembly)

T to A at 106393189 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Stop codon to Arginine at position 149 (*149R)

Ref Sequence

ENSEMBL: ENSMUSP00000082194 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000085113]

AlphaFold

Q9DAL7

Predicted Effect

probably null
Transcript: ENSMUST00000085113
AA Change: *149R

SMART Domains

Protein: ENSMUSP00000082194
Gene: ENSMUSG00000066382
AA Change: *149R

Domain	Start	End	E-Value	Type
IQ	10	32	8.38e-4	SMART
IQ	66	88	9.85e-1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000189866

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adora2b	A	G	11: 62,156,010 (GRCm39)	N153S	possibly damaging	Het
Afm	C	T	5: 90,672,765 (GRCm39)	T200I	probably benign	Het
Cyp2c67	T	C	19: 39,604,165 (GRCm39)	D397G	probably damaging	Het
Dnah9	A	G	11: 65,998,952 (GRCm39)	V1032A	probably benign	Het
Elovl7	T	G	13: 108,410,854 (GRCm39)	V143G	probably damaging	Het
Fhl4	T	C	10: 84,934,734 (GRCm39)	K16E	probably damaging	Het
Golga1	C	T	2: 38,924,161 (GRCm39)	C383Y	probably benign	Het
Gucy1a2	C	T	9: 3,865,409 (GRCm39)	R628*	probably null	Het
Hectd4	A	G	5: 121,466,481 (GRCm39)	D2432G	possibly damaging	Het
Kcnab1	T	A	3: 65,226,875 (GRCm39)	Y185N	probably damaging	Het
Lars1	G	T	18: 42,335,615 (GRCm39)	T1167K	probably benign	Het
Mib2	A	T	4: 155,739,715 (GRCm39)		probably null	Het
Mrps2	T	C	2: 28,358,348 (GRCm39)	V46A	probably benign	Het
Myo18b	T	C	5: 113,025,916 (GRCm39)	T45A	unknown	Het
Myo1e	C	T	9: 70,250,322 (GRCm39)		probably benign	Het
Or10ag59	A	G	2: 87,405,823 (GRCm39)	I132V	probably damaging	Het
Or4k39	T	A	2: 111,239,078 (GRCm39)	V106E	probably damaging	Het
Osbp2	A	T	11: 3,667,127 (GRCm39)	I8N	probably damaging	Het
Pcdhb22	A	T	18: 37,652,974 (GRCm39)	N481Y	probably damaging	Het
Pde3a	T	C	6: 141,433,263 (GRCm39)	W765R	probably damaging	Het
Phf11c	T	C	14: 59,630,586 (GRCm39)	T40A	probably benign	Het
Pih1d2	T	A	9: 50,533,177 (GRCm39)	S268R	probably benign	Het
Pkd1l2	T	C	8: 117,724,913 (GRCm39)	N2333D	probably damaging	Het
Prex1	A	G	2: 166,463,165 (GRCm39)	I62T	probably damaging	Het
Ptcd2	T	C	13: 99,463,219 (GRCm39)	N245S	possibly damaging	Het
Ripor3	C	A	2: 167,822,763 (GRCm39)	V933F	probably damaging	Het
Sanbr	A	G	11: 23,534,561 (GRCm39)	S105P	probably benign	Het
Sphk2	A	G	7: 45,360,480 (GRCm39)		probably null	Het
Tfcp2	T	G	15: 100,402,320 (GRCm39)	E492D	probably benign	Het
Ttn	C	T	2: 76,629,106 (GRCm39)	V14411I	possibly damaging	Het
Utp20	T	C	10: 88,628,549 (GRCm39)	Q915R	probably damaging	Het
Vmn2r45	C	A	7: 8,488,556 (GRCm39)	S158I	probably benign	Het

Other mutations in Iqcf5

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R6352:Iqcf5	UTSW	9	106,392,929 (GRCm39)	missense	possibly damaging	0.57
R7017:Iqcf5	UTSW	9	106,392,863 (GRCm39)	missense	possibly damaging	0.90
R7120:Iqcf5	UTSW	9	106,392,995 (GRCm39)	missense	probably damaging	1.00
R7988:Iqcf5	UTSW	9	106,393,020 (GRCm39)	missense	possibly damaging	0.84
R9660:Iqcf5	UTSW	9	106,393,168 (GRCm39)	missense	probably damaging	1.00
R9728:Iqcf5	UTSW	9	106,393,168 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-02-04